SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5orm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SXJ_A_SAMA258_0 (PUTATIVE METHYLTRANSFERASE)	5orm	CPPR-TELO1 (synthetic construct)	5 / 12	GLY A 226 GLY A 224 SER A 258 GLU A 233 ALA A 234	None	1.22A	3sxjA-5ormA: undetectable	3sxjA-5ormA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T7S_A_SAMA300_0 (PUTATIVE METHYLTRANSFERASE)	5orm	CPPR-TELO1 (synthetic construct)	5 / 12	GLY A 191 GLY A 189 SER A 223 GLU A 198 ALA A 199	None	1.24A	3t7sA-5ormA: undetectable	3t7sA-5ormA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T7S_A_SAMA300_0 (PUTATIVE METHYLTRANSFERASE)	5orm	CPPR-TELO1 (synthetic construct)	5 / 12	GLY A 226 GLY A 224 SER A 258 GLU A 233 ALA A 234	None	1.25A	3t7sA-5ormA: undetectable	3t7sA-5ormA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T7S_A_SAMA300_0 (PUTATIVE METHYLTRANSFERASE)	5orm	CPPR-TELO1 (synthetic construct)	5 / 12	GLY A 261 GLY A 259 SER A 293 GLU A 268 ALA A 269	None	1.33A	3t7sA-5ormA: undetectable	3t7sA-5ormA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T7S_A_SAMA300_0 (PUTATIVE METHYLTRANSFERASE)	5orm	CPPR-TELO1 (synthetic construct)	5 / 12	GLY A 331 GLY A 329 SER A 363 GLU A 338 ALA A 339	None	1.26A	3t7sA-5ormA: undetectable	3t7sA-5ormA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T7S_B_SAMB300_0 (PUTATIVE METHYLTRANSFERASE)	5orm	CPPR-TELO1 (synthetic construct)	5 / 12	GLY A 331 GLY A 329 SER A 363 GLU A 338 ALA A 339	None	1.28A	3t7sB-5ormA: undetectable	3t7sB-5ormA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L0Z_A_SAMA304_0 (PROBABLE RNA METHYLTRANSFERASE, TRMH FAMILY)	5orm	CPPR-TELO1 (synthetic construct)	5 / 12	THR A 290 GLY A 294 LEU A 260 LEU A 266 ALA A 269	None	1.04A	5l0zA-5ormA: undetectable	5l0zA-5ormA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWU_A_ACAA18_1 (WTFP-TAG,GP41)	5orm	CPPR-TELO1 (synthetic construct)	5 / 12	GLY A 294 SER A 293 GLU A 303 LEU A 307 GLU A 309	None	1.26A	5nwuA-5ormA: undetectable	5nwuA-5ormA: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3SXJ_A_SAMA258_0","PUTATIVE METHYLTRANSFERASE","5orm","CPPR-TELO1","synthetic construct",5,"GLY A 226;GLY A 224;SER A 258;GLU A 233;ALA A 234","None","1.22A","3sxjA-5ormA:undetectable","3sxjA-5ormA:undetectable"],["3T7S_A_SAMA300_0","PUTATIVE METHYLTRANSFERASE","5orm","CPPR-TELO1","synthetic construct",5,"GLY A 191;GLY A 189;SER A 223;GLU A 198;ALA A 199","None","1.24A","3t7sA-5ormA:undetectable","3t7sA-5ormA:undetectable"],["3T7S_A_SAMA300_0","PUTATIVE METHYLTRANSFERASE","5orm","CPPR-TELO1","synthetic construct",5,"GLY A 226;GLY A 224;SER A 258;GLU A 233;ALA A 234","None","1.25A","3t7sA-5ormA:undetectable","3t7sA-5ormA:undetectable"],["3T7S_A_SAMA300_0","PUTATIVE METHYLTRANSFERASE","5orm","CPPR-TELO1","synthetic construct",5,"GLY A 261;GLY A 259;SER A 293;GLU A 268;ALA A 269","None","1.33A","3t7sA-5ormA:undetectable","3t7sA-5ormA:undetectable"],["3T7S_A_SAMA300_0","PUTATIVE METHYLTRANSFERASE","5orm","CPPR-TELO1","synthetic construct",5,"GLY A 331;GLY A 329;SER A 363;GLU A 338;ALA A 339","None","1.26A","3t7sA-5ormA:undetectable","3t7sA-5ormA:undetectable"],["3T7S_B_SAMB300_0","PUTATIVE METHYLTRANSFERASE","5orm","CPPR-TELO1","synthetic construct",5,"GLY A 331;GLY A 329;SER A 363;GLU A 338;ALA A 339","None","1.28A","3t7sB-5ormA:undetectable","3t7sB-5ormA:undetectable"],["5L0Z_A_SAMA304_0","PROBABLE RNA METHYLTRANSFERASE, TRMH FAMILY","5orm","CPPR-TELO1","synthetic construct",5,"THR A 290;GLY A 294;LEU A 260;LEU A 266;ALA A 269","None","1.04A","5l0zA-5ormA:undetectable","5l0zA-5ormA:undetectable"],["5NWU_A_ACAA18_1","WTFP-TAG,GP41","5orm","CPPR-TELO1","synthetic construct",5,"GLY A 294;SER A 293;GLU A 303;LEU A 307;GLU A 309","None","1.26A","5nwuA-5ormA:undetectable","5nwuA-5ormA:20.00"]]