SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5osn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 10 LEU A 104
VAL C  46
VAL C 101
TYR C 105
LEU A 105
 None
 1.45A 1fkoA-5osnA:
undetectable		 1fkoA-5osnA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 7 GLY A 239
ASP C  35
ILE C  34
VAL C  33
 None
 0.81A 1p2yA-5osnA:
undetectable		 1p2yA-5osnA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 5osn CAPSID PROTEIN
CAPSID PROTEIN
(Enterovirus
E;
Enterovirus
E) 		4 / 8 PHE B 154
SER C  96
ALA B 161
ASN B 164
 None
 1.11A 1pnlA-5osnB:
undetectable
1pnlB-5osnB:
undetectable		 1pnlA-5osnB:
21.24
1pnlB-5osnB:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 ALA B 165
GLY B 163
ILE B 167
ILE B 207
HIS B 170
 None
 1.04A 1ve3A-5osnB:
undetectable		 1ve3A-5osnB:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 ALA B 165
GLY B 163
ILE B 167
ILE B 207
HIS B 170
 None
 1.00A 1ve3B-5osnB:
undetectable		 1ve3B-5osnB:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		3 / 3 ARG A 253
SER A 198
TYR A 202
 None
 0.79A 1x70A-5osnA:
undetectable		 1x70A-5osnA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 8 TYR B 214
PHE B 115
GLU B 213
THR C 212
 None
 1.01A 1ykiA-5osnB:
undetectable
1ykiB-5osnB:
undetectable		 1ykiA-5osnB:
22.57
1ykiB-5osnB:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 8 THR C 212
TYR B 214
PHE B 115
GLU B 213
 None
 0.99A 1ykiA-5osnC:
undetectable
1ykiB-5osnC:
undetectable		 1ykiA-5osnC:
22.64
1ykiB-5osnC:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 8 TYR B 214
PHE B 115
GLU B 213
THR C 212
 None
 1.00A 1ykiC-5osnB:
undetectable
1ykiD-5osnB:
undetectable		 1ykiC-5osnB:
22.57
1ykiD-5osnB:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 8 THR C 212
TYR B 214
PHE B 115
GLU B 213
 None
 1.03A 1ykiC-5osnC:
undetectable
1ykiD-5osnC:
undetectable		 1ykiC-5osnC:
22.64
1ykiD-5osnC:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 HIS B 199
GLY B 196
ASP B 194
GLY B 102
ASP B  82
 None
 1.01A 2f8lA-5osnB:
undetectable		 2f8lA-5osnB:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 HIS B 199
GLY B 196
ASP B 194
GLY B 103
ASP B  82
 None
 1.04A 2f8lA-5osnB:
undetectable		 2f8lA-5osnB:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 ALA C 221
LEU C 113
LEU C  99
LEU C  98
LEU C 227
 None
 1.08A 2qxsA-5osnC:
undetectable		 2qxsA-5osnC:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 5osn CAPSID PROTEIN
CAPSID PROTEIN
(Enterovirus
E;
Enterovirus
E) 		4 / 7 THR C  21
PRO C  22
VAL A 173
SER A 174
 None
 1.07A 2v41E-5osnC:
undetectable
2v41F-5osnC:
undetectable		 2v41E-5osnC:
22.81
2v41F-5osnC:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 5osn CAPSID PROTEIN
CAPSID PROTEIN
(Enterovirus
E;
Enterovirus
E) 		4 / 7 THR C  21
PRO C  22
VAL A 173
SER A 174
 None
 1.06A 2v41E-5osnC:
undetectable
2v41F-5osnC:
undetectable		 2v41E-5osnC:
22.81
2v41F-5osnC:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 5osn CAPSID PROTEIN
CAPSID PROTEIN
(Enterovirus
E;
Enterovirus
E) 		4 / 8 THR C  21
PRO C  22
VAL A 173
SER A 174
 None
 1.10A 2v41G-5osnC:
undetectable
2v41H-5osnC:
undetectable		 2v41G-5osnC:
22.81
2v41H-5osnC:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5osn CAPSID PROTEIN
CAPSID PROTEIN
(Enterovirus
E;
Enterovirus
E) 		3 / 3 TYR C 106
GLU A  63
THR C  16
 None
 0.80A 2y7hB-5osnC:
undetectable		 2y7hB-5osnC:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 9 MET A 247
ALA B 161
LEU C  98
VAL C 101
LEU A 104
 None
 1.32A 3fl9H-5osnA:
undetectable		 3fl9H-5osnA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 GLY B  75
HIS B 128
LEU B 204
VAL B 108
ILE B 224
 None
 1.08A 3g9eA-5osnB:
undetectable		 3g9eA-5osnB:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 GLY B  75
LEU B 204
VAL B 108
ILE B 224
HIS B 128
 None
 1.09A 3g9eA-5osnB:
undetectable		 3g9eA-5osnB:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 5osn CAPSID PROTEIN
CAPSID PROTEIN
(Enterovirus
E;
Enterovirus
E) 		3 / 3 GLU A  67
ASP C  18
ASP A 111
 None
 0.55A 3jb2A-5osnA:
undetectable		 3jb2A-5osnA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 5osn CAPSID PROTEIN
CAPSID PROTEIN
(Enterovirus
E;
Enterovirus
E) 		4 / 4 GLY A 256
TYR A 258
GLY B 159
ASP B 158
 None
 1.29A 3kl3A-5osnA:
undetectable		 3kl3A-5osnA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 6 SER B  19
VAL B 105
THR B  22
THR B  23
 None
 1.00A 3tneA-5osnB:
undetectable		 3tneA-5osnB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 7 GLY C  89
ILE C  90
VAL C  53
VAL C 219
 None
 0.71A 3ufnB-5osnC:
undetectable		 3ufnB-5osnC:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 6 ASP C  87
GLU C 191
GLY C 193
LEU C 180
 None
 1.10A 3w9tB-5osnC:
undetectable		 3w9tB-5osnC:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 6 ASP C  87
GLU C 191
GLY C 193
LEU C 180
 None
 1.10A 3w9tE-5osnC:
undetectable		 3w9tE-5osnC:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 6 ASP C  87
GLU C 191
GLY C 193
LEU C 180
 None
 1.11A 3w9tF-5osnC:
undetectable		 3w9tF-5osnC:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5osn CAPSID PROTEIN
CAPSID PROTEIN
(Enterovirus
E;
Enterovirus
E) 		4 / 8 ILE C  34
ASP C  35
ILE C  36
GLY A 239
 None
 0.76A 4acaC-5osnC:
undetectable		 4acaC-5osnC:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 6 ASN B  28
ALA B  26
THR B  23
LEU B  14
 None
 1.01A 4ejgD-5osnB:
undetectable		 4ejgD-5osnB:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 7 VAL C 166
SER A  42
GLN C 222
MET A  49
 None
K  C 301 (-4.8A)
K  C 301 (-3.6A)
None
 1.08A 4hxyB-5osnC:
undetectable		 4hxyB-5osnC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 8 ARG B 198
SER A 185
ALA A 181
SER A 179
 None
 1.07A 4lv9A-5osnB:
undetectable
4lv9B-5osnB:
undetectable		 4lv9A-5osnB:
19.03
4lv9B-5osnB:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		3 / 3 LEU C  98
MET C  94
TYR C 105
 None
 0.92A 4p6xG-5osnC:
undetectable		 4p6xG-5osnC:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 GLY A  84
ASP A 220
VAL A 121
VAL A 136
ILE A 116
 None
 0.98A 4q5mA-5osnA:
undetectable		 4q5mA-5osnA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 8 PHE A 110
ASP C  18
ASP C  17
TYR A 231
 None
 1.20A 4qb9D-5osnA:
undetectable		 4qb9D-5osnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.38A 4qvlV-5osnB:
undetectable
4qvlb-5osnB:
undetectable		 4qvlV-5osnB:
22.22
4qvlb-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.39A 4qvlH-5osnB:
undetectable
4qvlN-5osnB:
undetectable		 4qvlH-5osnB:
22.22
4qvlN-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.38A 4qvmV-5osnB:
undetectable
4qvmb-5osnB:
undetectable		 4qvmV-5osnB:
22.22
4qvmb-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.38A 4qvmH-5osnB:
undetectable
4qvmN-5osnB:
undetectable		 4qvmH-5osnB:
22.22
4qvmN-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.42A 4qvpV-5osnB:
undetectable
4qvpb-5osnB:
undetectable		 4qvpV-5osnB:
22.22
4qvpb-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.43A 4qvpH-5osnB:
undetectable
4qvpN-5osnB:
undetectable		 4qvpH-5osnB:
22.22
4qvpN-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.41A 4qvqV-5osnB:
undetectable
4qvqb-5osnB:
undetectable		 4qvqV-5osnB:
22.22
4qvqb-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.41A 4qvqH-5osnB:
undetectable
4qvqN-5osnB:
undetectable		 4qvqH-5osnB:
22.22
4qvqN-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.41A 4qvwV-5osnB:
undetectable
4qvwb-5osnB:
undetectable		 4qvwV-5osnB:
22.22
4qvwb-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.40A 4qvwH-5osnB:
undetectable
4qvwN-5osnB:
undetectable		 4qvwH-5osnB:
22.22
4qvwN-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.39A 4qw0V-5osnB:
undetectable
4qw0b-5osnB:
undetectable		 4qw0V-5osnB:
22.22
4qw0b-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.38A 4qw0H-5osnB:
undetectable
4qw0N-5osnB:
undetectable		 4qw0H-5osnB:
22.22
4qw0N-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.41A 4qw1V-5osnB:
undetectable
4qw1b-5osnB:
undetectable		 4qw1V-5osnB:
22.22
4qw1b-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.42A 4qw1H-5osnB:
undetectable
4qw1N-5osnB:
undetectable		 4qw1H-5osnB:
22.22
4qw1N-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.37A 4qw3V-5osnB:
undetectable
4qw3b-5osnB:
undetectable		 4qw3V-5osnB:
22.22
4qw3b-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.38A 4qw3H-5osnB:
undetectable
4qw3N-5osnB:
undetectable		 4qw3H-5osnB:
22.22
4qw3N-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 MET C  94
PRO C  93
ILE C  55
ASP C 114
ILE C 195
 None
None
None
K  C 301 (-4.0A)
None
 1.40A 4xe0A-5osnC:
undetectable		 4xe0A-5osnC:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 6 LEU C  52
GLU C  50
ILE C  69
PRO C  88
 None
 1.09A 4xi3C-5osnC:
undetectable		 4xi3C-5osnC:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 ILE A  90
VAL A 175
VAL A 173
PHE A 114
MET A 112
 SPH  A 301 (-4.1A)
SPH  A 301 (-4.9A)
None
SPH  A 301 ( 4.2A)
SPH  A 301 ( 4.2A)
 1.02A 4y0pA-5osnA:
undetectable		 4y0pA-5osnA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 LEU A 213
ILE A  90
VAL A 175
PHE A 114
MET A 112
 SPH  A 301 (-4.6A)
SPH  A 301 (-4.1A)
SPH  A 301 (-4.9A)
SPH  A 301 ( 4.2A)
SPH  A 301 ( 4.2A)
 0.99A 4y0rA-5osnA:
undetectable		 4y0rA-5osnA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		3 / 3 ALA B 229
TYR B  62
PRO B  54
 None
 0.70A 4zdyA-5osnB:
undetectable		 4zdyA-5osnB:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 4 VAL B 108
ALA B 181
ASN B 178
GLN B 171
 None
 1.45A 4zgfA-5osnB:
undetectable		 4zgfA-5osnB:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.35A 5bxnV-5osnB:
undetectable
5bxnb-5osnB:
undetectable		 5bxnV-5osnB:
22.62
5bxnb-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.37A 5bxnH-5osnB:
undetectable
5bxnN-5osnB:
undetectable		 5bxnH-5osnB:
22.62
5bxnN-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.41A 5cz7H-5osnB:
undetectable
5cz7N-5osnB:
undetectable		 5cz7H-5osnB:
22.22
5cz7N-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.37A 5d0xV-5osnB:
undetectable
5d0xb-5osnB:
undetectable		 5d0xV-5osnB:
22.22
5d0xb-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.37A 5d0xH-5osnB:
undetectable
5d0xN-5osnB:
undetectable		 5d0xH-5osnB:
22.22
5d0xN-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 12 LEU B 166
PHE C 218
ILE C 215
THR B 119
PHE B 156
 None
 1.24A 5fsaB-5osnB:
undetectable		 5fsaB-5osnB:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 5osn CAPSID PROTEIN
CAPSID PROTEIN
(Enterovirus
E;
Enterovirus
E) 		3 / 3 PRO B 211
ARG C  68
GLU B 213
 None
 0.95A 5j6hA-5osnB:
undetectable		 5j6hA-5osnB:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.41A 5l66V-5osnB:
undetectable
5l66b-5osnB:
undetectable		 5l66V-5osnB:
22.22
5l66b-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		5 / 11 SER B  57
THR B 233
THR B  52
GLY B  91
ALA B  58
 None
 1.40A 5l66H-5osnB:
undetectable
5l66N-5osnB:
undetectable		 5l66H-5osnB:
22.22
5l66N-5osnB:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		4 / 4 ILE B 207
LEU B 204
HIS B 170
ALA B 124
 None
 1.05A 6ck2C-5osnB:
undetectable
6ck2D-5osnB:
undetectable		 6ck2C-5osnB:
8.15
6ck2D-5osnB:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 5osn CAPSID PROTEIN
(Enterovirus
E) 		3 / 3 ARG A  99
GLY A  93
GLU A  94
 None
 0.54A 6fgdA-5osnA:
undetectable		 6fgdA-5osnA:
19.27