SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ov3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		5 / 11 SER A 314
LEU A 276
VAL A 267
SER A 319
ILE A 310
 None
 1.17A 2zbzA-5ov3A:
undetectable		 2zbzA-5ov3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		4 / 4 ASN A 170
ALA A 171
GLY A 173
THR A 198
 None
 1.02A 4bboC-5ov3A:
undetectable		 4bboC-5ov3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		5 / 12 VAL A  41
CYH A  30
PHE A  32
VAL A 318
LEU A  21
 None
 1.40A 4po0A-5ov3A:
undetectable		 4po0A-5ov3A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		4 / 6 GLY A  57
ASP A 340
ASP A  22
ASP A  52
 None
 1.05A 4uckB-5ov3A:
undetectable		 4uckB-5ov3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		3 / 3 TRP A  93
ILE A  89
SER A  85
 None
 1.00A 5gqbA-5ov3A:
undetectable		 5gqbA-5ov3A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		3 / 3 THR A 252
SER A 270
TYR A 277
 None
 0.87A 5jsdA-5ov3A:
2.0		 5jsdA-5ov3A:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		3 / 3 THR A 252
SER A 270
TYR A 277
 None
 0.87A 5jsdB-5ov3A:
undetectable		 5jsdB-5ov3A:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		3 / 3 THR A 252
SER A 270
TYR A 277
 None
 0.87A 5jsdC-5ov3A:
undetectable		 5jsdC-5ov3A:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		3 / 3 THR A 252
SER A 270
TYR A 277
 None
 0.87A 5jseA-5ov3A:
undetectable		 5jseA-5ov3A:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		3 / 3 THR A 252
SER A 270
TYR A 277
 None
 0.87A 5jseB-5ov3A:
undetectable		 5jseB-5ov3A:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		3 / 3 THR A 252
SER A 270
TYR A 277
 None
 0.87A 5jseC-5ov3A:
undetectable		 5jseC-5ov3A:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 5ov3 RETINOBLASTOMA-BINDI
NG PROTEIN 5
(Mus
musculus) 		4 / 5 VAL A  95
LEU A  72
CYH A  73
ASP A  77
 None
 1.18A 5vcvA-5ov3A:
undetectable		 5vcvA-5ov3A:
16.22