SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ov6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		5 / 10 ALA A 164
GLY A 124
GLU A 112
LEU A 117
PRO A 118
 None
 1.15A 1cmcA-5ov6A:
undetectable
1cmcB-5ov6A:
undetectable		 1cmcA-5ov6A:
16.83
1cmcB-5ov6A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		5 / 12 ALA A 164
GLY A 124
GLU A 112
LEU A 117
PRO A 118
 None
 1.14A 1mj2C-5ov6A:
undetectable
1mj2D-5ov6A:
undetectable		 1mj2C-5ov6A:
16.50
1mj2D-5ov6A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		5 / 12 ALA A 164
GLY A 124
GLU A 112
LEU A 117
PRO A 118
 None
 1.14A 1mjoC-5ov6A:
undetectable
1mjoD-5ov6A:
undetectable		 1mjoC-5ov6A:
16.50
1mjoD-5ov6A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 8 LEU A  87
ARG A 228
VAL A 195
GLY A 196
 None
 0.82A 2po5A-5ov6A:
undetectable		 2po5A-5ov6A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 7 PRO A 244
VAL A 243
GLU A 307
PRO A 266
 None
 0.98A 2v2gA-5ov6A:
undetectable
2v2gB-5ov6A:
undetectable		 2v2gA-5ov6A:
20.57
2v2gB-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 7 PRO A 266
PRO A 244
VAL A 243
GLU A 307
 None
 1.00A 2v2gA-5ov6A:
undetectable
2v2gB-5ov6A:
undetectable		 2v2gA-5ov6A:
20.57
2v2gB-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 7 PRO A 244
VAL A 243
GLU A 307
PRO A 266
 None
 1.05A 2v2gC-5ov6A:
undetectable
2v2gD-5ov6A:
undetectable		 2v2gC-5ov6A:
20.57
2v2gD-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 7 PRO A 266
PRO A 244
VAL A 243
GLU A 307
 None
 0.97A 2v2gC-5ov6A:
undetectable
2v2gD-5ov6A:
undetectable		 2v2gC-5ov6A:
20.57
2v2gD-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 8 PRO A 244
VAL A 243
GLU A 307
PRO A 266
 None
 0.90A 2v41C-5ov6A:
undetectable
2v41D-5ov6A:
undetectable		 2v41C-5ov6A:
20.57
2v41D-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 8 PRO A 266
PRO A 244
VAL A 243
GLU A 307
 None
 0.91A 2v41C-5ov6A:
undetectable
2v41D-5ov6A:
undetectable		 2v41C-5ov6A:
20.57
2v41D-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 7 PRO A 244
VAL A 243
GLU A 307
PRO A 266
 None
 1.04A 2v41E-5ov6A:
undetectable
2v41F-5ov6A:
undetectable		 2v41E-5ov6A:
20.57
2v41F-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 7 PRO A 266
PRO A 244
VAL A 243
GLU A 307
 None
 0.88A 2v41E-5ov6A:
undetectable
2v41F-5ov6A:
undetectable		 2v41E-5ov6A:
20.57
2v41F-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 8 PRO A 244
VAL A 243
GLU A 307
PRO A 266
 None
 1.02A 2v41G-5ov6A:
undetectable
2v41H-5ov6A:
undetectable		 2v41G-5ov6A:
20.57
2v41H-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 8 PRO A 266
PRO A 244
VAL A 243
GLU A 307
 None
 0.98A 2v41G-5ov6A:
undetectable
2v41H-5ov6A:
undetectable		 2v41G-5ov6A:
20.57
2v41H-5ov6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 5 ARG A 174
ALA A 170
ASP A 101
GLU A 100
 None
 1.48A 2xrzA-5ov6A:
undetectable		 2xrzA-5ov6A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		3 / 3 ASN A  82
HIS A  78
VAL A  77
 AWQ  A 401 (-3.8A)
None
None
 0.80A 3elzB-5ov6A:
2.4		 3elzB-5ov6A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		5 / 11 ASP A 104
LEU A 106
PHE A 114
ILE A 190
SER A 191
 None
 1.29A 3o94A-5ov6A:
undetectable		 3o94A-5ov6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		5 / 11 ASP A 104
LEU A 106
PHE A 114
ILE A 190
SER A 191
 None
 1.27A 3o94C-5ov6A:
undetectable		 3o94C-5ov6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		5 / 11 ASP A 104
LEU A 106
PHE A 114
ILE A 190
SER A 191
 None
 1.28A 3o94D-5ov6A:
undetectable		 3o94D-5ov6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 5 THR A 260
GLY A 247
VAL A 195
PRO A 193
 None
 0.99A 4grkA-5ov6A:
6.5		 4grkA-5ov6A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		3 / 3 ARG A 250
GLU A 187
TYR A 248
 None
 0.95A 4r29D-5ov6A:
undetectable		 4r29D-5ov6A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 6 GLU A 230
PRO A 193
GLY A 196
ARG A  99
 None
 1.23A 5jcnB-5ov6A:
undetectable		 5jcnB-5ov6A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		5 / 10 ARG A 174
ALA A 170
GLY A 176
ILE A 123
LEU A 117
 None
 1.22A 5oy01-5ov6A:
undetectable
5oy07-5ov6A:
undetectable		 5oy01-5ov6A:
12.70
5oy07-5ov6A:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 8 GLY A 198
ARG A 130
GLN A 133
ASP A 104
 None
AWQ  A 401 (-3.8A)
None
None
 0.90A 5vlmA-5ov6A:
undetectable		 5vlmA-5ov6A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 8 GLY A 198
ARG A 130
GLN A 133
ASP A 104
 None
AWQ  A 401 (-3.8A)
None
None
 0.80A 5vlmB-5ov6A:
undetectable		 5vlmB-5ov6A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 5ov6 PORPHOBILINOGEN
DEAMINASE
(Bacillus
megaterium) 		4 / 7 GLN A  17
ILE A 202
GLN A  28
TRP A  20
 None
 1.13A 5vlmC-5ov6A:
undetectable		 5vlmC-5ov6A:
23.64