SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ovn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
GLY A 189
TYR A 317
None
0.74A 1fk9A-5ovnA:
26.6
1fk9A-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.79A 1fk9A-5ovnA:
26.6
1fk9A-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.71A 1fk9A-5ovnB:
8.3
1fk9A-5ovnB:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 10 LEU A  99
VAL A 105
TYR A 180
GLY A 189
LEU A 233
TYR A 317
None
0.79A 1fkoA-5ovnA:
23.3
1fkoA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 PRO A  94
LEU A  99
TRP A 228
LEU A 233
TYR A 317
None
1.25A 1fkpA-5ovnA:
26.0
1fkpA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 PRO A  94
LEU A  99
VAL A 105
GLY A 189
TYR A 317
None
0.92A 1fkpA-5ovnA:
26.0
1fkpA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 PRO A  94
LEU A  99
VAL A 105
LEU A 233
TYR A 317
None
1.04A 1fkpA-5ovnA:
26.0
1fkpA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
GLY A 189
TYR A 317
None
0.78A 1ikwA-5ovnA:
26.9
1ikwA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.72A 1ikwA-5ovnB:
10.4
1ikwA-5ovnB:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 LEU A  99
LYS A 102
VAL A 105
GLY A 189
TYR A 317
None
0.64A 1jkhA-5ovnA:
26.5
1jkhB-5ovnA:
15.9
1jkhA-5ovnA:
55.00
1jkhB-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.71A 1jkhA-5ovnA:
26.5
1jkhB-5ovnA:
15.9
1jkhA-5ovnA:
55.00
1jkhB-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 8 LEU A  99
VAL A 105
GLY A 189
TYR A 317
None
0.82A 1jlfA-5ovnA:
25.8
1jlfB-5ovnA:
16.0
1jlfA-5ovnA:
55.00
1jlfB-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 11 LEU A  99
VAL A 105
PRO A 225
LEU A 233
PRO A 235
TYR A 317
None
0.72A 1klmA-5ovnA:
25.9
1klmA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.48A 1lw0A-5ovnB:
10.5
1lw0A-5ovnB:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.50A 1lwcA-5ovnB:
9.7
1lwcA-5ovnB:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 11 PRO A  94
LEU A  99
LYS A 102
VAL A 105
GLY A 189
TYR A 317
None
0.94A 1lwcA-5ovnA:
26.3
1lwcA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 11 PRO A  94
LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.98A 1lwcA-5ovnA:
26.3
1lwcA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 7 LEU A  99
VAL A 105
GLY A 189
TYR A 317
None
0.63A 1lweA-5ovnA:
26.7
1lweA-5ovnA:
56.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 7 VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.37A 1lweA-5ovnB:
17.5
1lweA-5ovnB:
60.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.51A 1s1uA-5ovnB:
9.6
1s1uA-5ovnB:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 8 VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.28A 1s1xA-5ovnB:
11.1
1s1xA-5ovnB:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 7 ASP A 109
TYR A 182
MET A 183
ASP A 184
None
1.05A 1t03A-5ovnA:
20.8
1t03A-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 7 ASP A 109
TYR A 182
MET A 183
ASP A 185
None
0.95A 1t03A-5ovnA:
20.8
1t03A-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 7 ASP B 109
MET B 183
ASP B 184
ASP B 185
None
1.31A 1t03A-5ovnB:
8.3
1t03A-5ovnB:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 7 TYR B 182
MET B 183
ASP B 184
ASP B 185
None
1.22A 1t03A-5ovnB:
8.3
1t03A-5ovnB:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
GLY A 189
TYR A 317
None
0.75A 2hndA-5ovnA:
26.4
2hndA-5ovnA:
56.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.74A 2hndA-5ovnA:
26.4
2hndA-5ovnA:
56.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.49A 2hndA-5ovnB:
9.3
2hndA-5ovnB:
60.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
GLY A 189
TYR A 317
None
0.79A 2hnyA-5ovnA:
26.3
2hnyA-5ovnA:
56.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.73A 2hnyA-5ovnA:
26.3
2hnyA-5ovnA:
56.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.55A 2hnyA-5ovnB:
10.4
2hnyA-5ovnB:
60.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 LEU A 521
LEU A 428
ILE A 444
VAL A 502
ILE A 505
None
1.19A 2uxoB-5ovnA:
undetectable
2uxoB-5ovnA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
3 / 3 ARG B 376
GLU B 386
SER B 405
None
0.86A 2xctD-5ovnB:
undetectable
2xctD-5ovnB:
8.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 LEU B 278
ASN B 280
TRP B 294
LEU B 256
GLU B 301
None
1.45A 3bgrA-5ovnB:
10.3
3bgrB-5ovnB:
11.1
3bgrA-5ovnB:
59.52
3bgrB-5ovnB:
59.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8F_A_DM1A127_1
(TRANSCRIPTIONAL
REGULATOR, PADR-LIKE
FAMILY)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 ALA B 298
VAL B 302
ALA B 260
MET B 282
TRP B 294
None
1.22A 3f8fA-5ovnB:
0.7
3f8fB-5ovnB:
undetectable
3f8fA-5ovnB:
24.22
3f8fB-5ovnB:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
3 / 3 THR A 215
GLU A 202
HIS A 197
None
0.75A 3g1uB-5ovnA:
undetectable
3g1uB-5ovnA:
10.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 9 LEU A  99
LYS A 102
TRP A 228
LEU A 233
TYR A 317
None
0.89A 3hvtA-5ovnA:
10.4
3hvtA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 9 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.84A 3hvtA-5ovnA:
10.4
3hvtA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 9 LYS A 102
VAL A 105
GLY A 189
LEU A 233
TYR A 317
None
1.00A 3hvtA-5ovnA:
10.4
3hvtA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 9 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.89A 3hvtA-5ovnB:
9.1
3hvtA-5ovnB:
59.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 12 LEU A  99
LYS A 102
VAL A 105
GLY A 189
LEU A 233
TYR A 317
None
0.78A 3mecA-5ovnA:
26.9
3mecA-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 12 LEU A  99
VAL A 105
GLY A 189
LEU A 233
PRO A 235
TYR A 317
None
0.93A 3mecA-5ovnA:
26.9
3mecA-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.78A 3mecA-5ovnB:
10.2
3mecA-5ovnB:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.83A 3meeA-5ovnA:
26.9
3meeA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 PRO A  94
LEU A  99
VAL A 105
LEU A 233
TYR A 317
None
1.00A 3meeA-5ovnA:
26.9
3meeA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
GLY A 189
TYR A 317
None
0.75A 3qipA-5ovnA:
26.9
3qipA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.70A 3qipA-5ovnA:
26.9
3qipA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.50A 3qipA-5ovnB:
10.4
3qipA-5ovnB:
59.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 4 LYS B 216
GLN B 104
ILE B 179
LEU B 208
None
1.35A 3qt0A-5ovnB:
undetectable
3qt0A-5ovnB:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 PHE B 170
ILE B 186
THR B 106
LEU B 192
LEU B 177
None
1.24A 3s79A-5ovnB:
undetectable
3s79A-5ovnB:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 LEU B 288
PHE A 531
GLN B 257
VAL A 535
ILE A 503
None
1.43A 4b3aA-5ovnB:
undetectable
4b3aA-5ovnB:
14.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3O_A_EFZA1557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 9 LEU A  99
LYS A 102
VAL A 105
GLY A 189
LEU A 233
TYR A 317
None
0.72A 4b3oA-5ovnA:
28.3
4b3oA-5ovnA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3O_A_EFZA1557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 9 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.65A 4b3oA-5ovnB:
10.1
4b3oA-5ovnB:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 7 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.90A 4b3qA-5ovnA:
26.5
4b3qA-5ovnA:
55.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 LEU B 253
LEU B 256
LEU B 259
ALA B 260
ALA B 277
None
0.88A 4fn9A-5ovnB:
undetectable
4fn9A-5ovnB:
15.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 PRO A  94
LEU A  99
LYS A 102
VAL A 105
TYR A 317
None
1.03A 4idkA-5ovnA:
26.1
4idkA-5ovnA:
53.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 PRO A  94
LEU A  99
LYS A 102
VAL A 105
TYR A 317
None
1.04A 4ifyA-5ovnA:
26.1
4ifyA-5ovnA:
53.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 5 MET A 281
LEU A 278
ARG A 299
SER A 290
None
1.42A 4kmmB-5ovnA:
undetectable
4kmmB-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 8 ARG B 395
TYR B 417
ASP B  75
GLU B  78
None
1.12A 4kr4C-5ovnB:
undetectable
4kr4C-5ovnB:
11.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PUO_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 9 PRO A  94
LEU A  99
VAL A 105
LEU A 233
TYR A 317
None
1.03A 4puoA-5ovnA:
25.2
4puoA-5ovnA:
53.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 8 LEU A  99
VAL A 105
LEU A 233
TYR A 317
None
0.71A 4pwdC-5ovnA:
25.0
4pwdC-5ovnA:
53.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 8 LYS B 102
VAL B 105
TYR B 180
TYR B 187
None
0.58A 4q0bA-5ovnB:
10.1
4q0bA-5ovnB:
59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 9 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.77A 4q0bC-5ovnA:
25.0
4q0bC-5ovnA:
53.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 HIS A 197
LEU A 108
ILE A 179
GLU A 222
LEU A 220
None
1.13A 4r88A-5ovnA:
undetectable
4r88A-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 HIS A 197
LEU A 108
ILE A 179
GLU A 222
LEU A 220
None
1.12A 4r88B-5ovnA:
undetectable
4r88B-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 HIS A 197
LEU A 108
ILE A 179
GLU A 222
LEU A 220
None
1.16A 4r88C-5ovnA:
undetectable
4r88C-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 HIS A 197
LEU A 108
ILE A 179
GLU A 222
LEU A 220
None
1.13A 4r88D-5ovnA:
undetectable
4r88D-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 HIS A 197
LEU A 108
ILE A 179
GLU A 222
LEU A 220
None
1.16A 4r88E-5ovnA:
undetectable
4r88E-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 HIS A 197
LEU A 108
ILE A 179
GLU A 222
LEU A 220
None
1.15A 4r88F-5ovnA:
undetectable
4r88F-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))
5ovn POL PROTEIN
POL PROTEIN

(Feline
immunodeficiency
virus;
Feline
immunodeficiency
virus)
5 / 12 ARG B 142
GLY A  86
ALA A  87
ALA B 128
TRP B  56
None
1.30A 4ryaA-5ovnB:
undetectable
4ryaA-5ovnB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 8 ALA A 477
ALA A 481
ALA A 457
ALA A 454
None
0.79A 4twdF-5ovnA:
undetectable
4twdG-5ovnA:
undetectable
4twdH-5ovnA:
undetectable
4twdI-5ovnA:
undetectable
4twdJ-5ovnA:
undetectable
4twdF-5ovnA:
14.38
4twdG-5ovnA:
14.38
4twdH-5ovnA:
14.38
4twdI-5ovnA:
14.38
4twdJ-5ovnA:
14.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.84A 5cymA-5ovnA:
25.9
5cymA-5ovnA:
53.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 PRO A  94
LEU A  99
VAL A 105
LEU A 233
TYR A 317
None
1.02A 5cymA-5ovnA:
25.9
5cymA-5ovnA:
53.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 12 PRO A  94
LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.98A 5cyqA-5ovnA:
25.3
5cyqA-5ovnA:
53.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 LEU A  99
VAL A 105
GLY A 189
LEU A 233
TYR A 317
None
0.80A 5hbmA-5ovnA:
26.8
5hbmA-5ovnA:
53.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 6 ASP A 109
GLY A 111
ASP A 112
ASP A 184
None
1.32A 5hp1A-5ovnA:
27.9
5hp1A-5ovnA:
55.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 PHE B 170
ILE B 186
THR B 106
LEU B 192
LEU B 177
None
1.24A 5jkvA-5ovnB:
undetectable
5jkvA-5ovnB:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
3 / 3 THR B 393
SER B 394
TYR B 417
None
0.85A 5jsdA-5ovnB:
undetectable
5jsdA-5ovnB:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
3 / 3 THR B 393
SER B 394
TYR B 417
None
0.84A 5jsdC-5ovnB:
undetectable
5jsdC-5ovnB:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 5 TYR B 180
ILE B 186
LEU B  91
GLY B  92
None
0.84A 5kmdC-5ovnB:
undetectable
5kmdD-5ovnB:
undetectable
5kmdC-5ovnB:
13.57
5kmdD-5ovnB:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
3 / 3 LYS B 327
GLN B 268
ASN B 423
None
1.02A 5l2tA-5ovnB:
undetectable
5l2tA-5ovnB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 ILE A 186
ILE A 188
LEU A 177
ILE A 166
ASN A 165
None
0.90A 5vkqA-5ovnA:
undetectable
5vkqD-5ovnA:
undetectable
5vkqA-5ovnA:
undetectable
5vkqD-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 ILE A 166
ASN A 165
ILE A 186
ILE A 188
LEU A 177
None
0.87A 5vkqA-5ovnA:
undetectable
5vkqB-5ovnA:
undetectable
5vkqA-5ovnA:
undetectable
5vkqB-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
4 / 9 ILE A 166
ILE A 186
ILE A 188
LEU A 177
None
0.75A 5vkqB-5ovnA:
undetectable
5vkqC-5ovnA:
undetectable
5vkqB-5ovnA:
undetectable
5vkqC-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 ILE A 166
ASN A 165
ILE A 186
ILE A 188
LEU A 177
None
0.88A 5vkqC-5ovnA:
undetectable
5vkqD-5ovnA:
undetectable
5vkqC-5ovnA:
undetectable
5vkqD-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)
5ovn POL PROTEIN
POL PROTEIN

(Feline
immunodeficiency
virus;
Feline
immunodeficiency
virus)
3 / 3 ARG A 172
PHE B 143
ARG B 141
None
1.20A 5y9yA-5ovnA:
undetectable
5y9yA-5ovnA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 10 LEU A  99
LYS A 102
VAL A 105
GLY A 189
LEU A 233
TYR A 317
None
0.80A 6bsgA-5ovnA:
25.9
6bsgA-5ovnA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LYS B 102
VAL B 105
TYR B 180
TYR B 187
GLY B 189
None
0.93A 6bsgA-5ovnB:
10.5
6bsgA-5ovnB:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
6 / 10 LEU A  99
LYS A 102
VAL A 105
GLY A 189
LEU A 233
TYR A 317
None
0.79A 6bsiA-5ovnA:
25.8
6bsiA-5ovnA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.91A 6bsjA-5ovnA:
28.8
6bsjA-5ovnA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 10 LYS A 102
VAL A 105
GLY A 189
LEU A 233
TYR A 317
None
0.89A 6bsjA-5ovnA:
28.8
6bsjA-5ovnA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
5ovn POL PROTEIN
POL PROTEIN

(Feline
immunodeficiency
virus;
Feline
immunodeficiency
virus)
4 / 6 THR B 364
ARG B 356
PRO A 411
ILE A 403
None
1.42A 6ef6A-5ovnB:
undetectable
6ef6A-5ovnB:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 LEU A  99
LYS A 102
VAL A 105
LEU A 233
TYR A 317
None
0.80A 6eliA-5ovnA:
25.6
6eliA-5ovnA:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 12 PRO A  94
LEU A  99
VAL A 105
LEU A 233
TYR A 317
None
1.03A 6eliA-5ovnA:
25.6
6eliA-5ovnA:
48.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)
5ovn POL PROTEIN
(Feline
immunodeficiency
virus)
5 / 11 ILE A 348
ALA A  97
HIS A  95
SER A 379
ALA A 326
None
1.35A 6ieyA-5ovnA:
undetectable
6ieyB-5ovnA:
undetectable
6ieyA-5ovnA:
undetectable
6ieyB-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
5ovn POL PROTEIN
POL PROTEIN

(Feline
immunodeficiency
virus;
Feline
immunodeficiency
virus)
3 / 3 ASN B 135
PRO A  94
GLN A 268
None
0.86A 6jnhA-5ovnB:
undetectable
6jnhA-5ovnB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
5ovn POL PROTEIN
POL PROTEIN

(Feline
immunodeficiency
virus;
Feline
immunodeficiency
virus)
3 / 3 ASN B 135
PRO A  94
GLN A 268
None
0.84A 6jogA-5ovnB:
undetectable
6jogA-5ovnB:
undetectable