SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ovt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.51A 2f162-5ovtA:
17.0		 2f162-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.51A 2f16N-5ovtA:
17.1		 2f16N-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 ALA A 170
GLY A 166
LEU A 145
SER A 141
GLY A 138
 None
None
None
None
PO4  A 301 ( 3.7A)
 1.04A 3g2oB-5ovtA:
undetectable		 3g2oB-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.47A 3mg02-5ovtA:
17.0
3mg0V-5ovtA:
19.5		 3mg02-5ovtA:
22.63
3mg0V-5ovtA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
LYS A  37
GLY A  50
ALA A  52
SER A 139
 PO4  A 301 ( 4.5A)
None
PO4  A 301 (-4.1A)
None
PO4  A 301 (-3.0A)
 0.44A 3mg0K-5ovtA:
18.1
3mg0L-5ovtA:
14.8		 3mg0K-5ovtA:
18.96
3mg0L-5ovtA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 3mg0N-5ovtA:
5.7		 3mg0N-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
LYS A  37
GLY A  50
ALA A  52
SER A 139
 PO4  A 301 ( 4.5A)
None
PO4  A 301 (-4.1A)
None
PO4  A 301 (-3.0A)
 0.43A 3mg0Y-5ovtA:
9.4
3mg0Z-5ovtA:
5.9		 3mg0Y-5ovtA:
18.96
3mg0Z-5ovtA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qvlV-5ovtA:
18.0
4qvlb-5ovtA:
3.6		 4qvlV-5ovtA:
20.34
4qvlb-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.46A 4qvlH-5ovtA:
7.7
4qvlN-5ovtA:
5.8		 4qvlH-5ovtA:
20.34
4qvlN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qvmV-5ovtA:
19.6
4qvmb-5ovtA:
3.6		 4qvmV-5ovtA:
20.34
4qvmb-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qvmH-5ovtA:
7.6
4qvmN-5ovtA:
5.8		 4qvmH-5ovtA:
20.34
4qvmN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qvnV-5ovtA:
19.6
4qvnb-5ovtA:
3.9		 4qvnV-5ovtA:
20.34
4qvnb-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.44A 4qvnH-5ovtA:
7.6
4qvnN-5ovtA:
5.7		 4qvnH-5ovtA:
20.34
4qvnN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qvpV-5ovtA:
19.6
4qvpb-5ovtA:
3.6		 4qvpV-5ovtA:
20.34
4qvpb-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.44A 4qvpH-5ovtA:
7.6
4qvpN-5ovtA:
5.8		 4qvpH-5ovtA:
20.34
4qvpN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qvqV-5ovtA:
19.7
4qvqb-5ovtA:
3.8		 4qvqV-5ovtA:
20.34
4qvqb-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 9 THR A   1
LYS A  37
ILE A  48
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.85A 4qvqK-5ovtA:
18.0
4qvqL-5ovtA:
14.8		 4qvqK-5ovtA:
18.96
4qvqL-5ovtA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qvqH-5ovtA:
7.6
4qvqN-5ovtA:
5.7		 4qvqH-5ovtA:
20.34
4qvqN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 9 THR A   1
LYS A  37
ILE A  48
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.84A 4qvqY-5ovtA:
18.0
4qvqZ-5ovtA:
5.1		 4qvqY-5ovtA:
18.96
4qvqZ-5ovtA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.47A 4qvwV-5ovtA:
18.1
4qvwb-5ovtA:
3.6		 4qvwV-5ovtA:
20.34
4qvwb-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.47A 4qvwH-5ovtA:
7.6
4qvwN-5ovtA:
5.7		 4qvwH-5ovtA:
20.34
4qvwN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qw0V-5ovtA:
19.6
4qw0b-5ovtA:
17.1		 4qw0V-5ovtA:
20.34
4qw0b-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qw0H-5ovtA:
7.6
4qw0N-5ovtA:
5.7		 4qw0H-5ovtA:
20.34
4qw0N-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.46A 4qw1V-5ovtA:
19.6
4qw1b-5ovtA:
3.6		 4qw1V-5ovtA:
20.34
4qw1b-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.46A 4qw1H-5ovtA:
8.3
4qw1N-5ovtA:
5.8		 4qw1H-5ovtA:
20.34
4qw1N-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.46A 4qw3V-5ovtA:
18.0
4qw3b-5ovtA:
3.6		 4qw3V-5ovtA:
20.34
4qw3b-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 4qw3H-5ovtA:
7.5
4qw3N-5ovtA:
5.7		 4qw3H-5ovtA:
20.34
4qw3N-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.46A 4qwuV-5ovtA:
18.0
4qwub-5ovtA:
3.6		 4qwuV-5ovtA:
20.34
4qwub-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.46A 4qwuH-5ovtA:
8.3
4qwuN-5ovtA:
5.7		 4qwuH-5ovtA:
20.34
4qwuN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 LEU A  88
LEU A  84
ALA A  59
LEU A  58
TYR A  61
 None
 0.92A 4wg0B-5ovtA:
undetectable
4wg0C-5ovtA:
undetectable
4wg0D-5ovtA:
undetectable		 4wg0B-5ovtA:
undetectable
4wg0C-5ovtA:
undetectable
4wg0D-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 LEU A  88
LEU A  84
ALA A  59
LEU A  58
TYR A  61
 None
 0.91A 4wg0D-5ovtA:
undetectable
4wg0E-5ovtA:
undetectable
4wg0F-5ovtA:
undetectable		 4wg0D-5ovtA:
undetectable
4wg0E-5ovtA:
undetectable
4wg0F-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 ALA A  59
LEU A  58
TYR A  61
LEU A  88
LEU A  84
 None
 0.93A 4wg0C-5ovtA:
undetectable
4wg0D-5ovtA:
undetectable
4wg0E-5ovtA:
undetectable		 4wg0C-5ovtA:
undetectable
4wg0D-5ovtA:
undetectable
4wg0E-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 LEU A  88
LEU A  84
ALA A  59
LEU A  58
TYR A  61
 None
 0.92A 4wg0F-5ovtA:
undetectable
4wg0G-5ovtA:
undetectable
4wg0H-5ovtA:
undetectable		 4wg0F-5ovtA:
undetectable
4wg0G-5ovtA:
undetectable
4wg0H-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 ALA A  59
LEU A  58
TYR A  61
LEU A  88
LEU A  84
 None
 0.94A 4wg0E-5ovtA:
undetectable
4wg0F-5ovtA:
undetectable
4wg0G-5ovtA:
undetectable		 4wg0E-5ovtA:
undetectable
4wg0F-5ovtA:
undetectable
4wg0G-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 LEU A  88
LEU A  84
ALA A  59
LEU A  58
TYR A  61
 None
 0.92A 4wg0H-5ovtA:
undetectable
4wg0I-5ovtA:
undetectable
4wg0J-5ovtA:
undetectable		 4wg0H-5ovtA:
undetectable
4wg0I-5ovtA:
undetectable
4wg0J-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 ALA A  59
LEU A  58
TYR A  61
LEU A  88
LEU A  84
 None
 0.91A 4wg0G-5ovtA:
undetectable
4wg0H-5ovtA:
undetectable
4wg0I-5ovtA:
undetectable		 4wg0G-5ovtA:
undetectable
4wg0H-5ovtA:
undetectable
4wg0I-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 LEU A  88
LEU A  84
ALA A  59
LEU A  58
TYR A  61
 None
 0.92A 4wg0J-5ovtA:
undetectable
4wg0K-5ovtA:
undetectable
4wg0L-5ovtA:
undetectable		 4wg0J-5ovtA:
undetectable
4wg0K-5ovtA:
undetectable
4wg0L-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 ALA A  59
LEU A  58
TYR A  61
LEU A  88
LEU A  84
 None
 0.94A 4wg0I-5ovtA:
undetectable
4wg0J-5ovtA:
undetectable
4wg0K-5ovtA:
undetectable		 4wg0I-5ovtA:
undetectable
4wg0J-5ovtA:
undetectable
4wg0K-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 ALA A  59
LEU A  58
TYR A  61
LEU A  88
LEU A  84
 None
 0.91A 4wg0K-5ovtA:
undetectable
4wg0L-5ovtA:
undetectable
4wg0M-5ovtA:
undetectable		 4wg0K-5ovtA:
undetectable
4wg0L-5ovtA:
undetectable
4wg0M-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 5bxnV-5ovtA:
19.6
5bxnb-5ovtA:
3.6		 5bxnV-5ovtA:
20.34
5bxnb-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.44A 5bxnH-5ovtA:
5.0
5bxnN-5ovtA:
5.8		 5bxnH-5ovtA:
20.34
5bxnN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 5cz7H-5ovtA:
5.0
5cz7N-5ovtA:
5.7		 5cz7H-5ovtA:
20.34
5cz7N-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 5d0xV-5ovtA:
19.6
5d0xb-5ovtA:
3.6		 5d0xV-5ovtA:
20.34
5d0xb-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.46A 5d0xH-5ovtA:
7.6
5d0xN-5ovtA:
5.7		 5d0xH-5ovtA:
20.34
5d0xN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 PHE A  62
TYR A 137
THR A 127
ARG A 126
ILE A  77
 None
 1.28A 5ifuA-5ovtA:
undetectable		 5ifuA-5ovtA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 5l5zV-5ovtA:
19.7
5l5zb-5ovtA:
3.6		 5l5zV-5ovtA:
20.34
5l5zb-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 5l5zH-5ovtA:
7.6
5l5zN-5ovtA:
5.8		 5l5zH-5ovtA:
20.34
5l5zN-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.44A 5l66V-5ovtA:
19.7
5l66b-5ovtA:
3.6		 5l66V-5ovtA:
20.34
5l66b-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 11 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.45A 5l66H-5ovtA:
7.6
5l66N-5ovtA:
5.8		 5l66H-5ovtA:
20.34
5l66N-5ovtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.46A 5lf3b-5ovtA:
17.0		 5lf3b-5ovtA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.44A 5lf3N-5ovtA:
17.1		 5lf3N-5ovtA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.43A 5lf7V-5ovtA:
19.5
5lf7b-5ovtA:
17.1		 5lf7V-5ovtA:
undetectable
5lf7b-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.42A 5lf7H-5ovtA:
19.4
5lf7N-5ovtA:
17.2		 5lf7H-5ovtA:
undetectable
5lf7N-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5ovt BPH
(Thiobacillus
denitrificans) 		3 / 3 HIS A 174
SER A 177
LYS A   1
 None
None
PO4  A 301 ( 4.1A)
 1.49A 5os7A-5ovtA:
undetectable		 5os7A-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 5ovt BPH
(Thiobacillus
denitrificans) 		4 / 7 ASP A  17
THR A  18
LEU A  19
THR A   1
 None
None
None
PO4  A 301 ( 4.5A)
 1.03A 5ov9A-5ovtA:
undetectable		 5ov9A-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 5ovt BPH
(Thiobacillus
denitrificans) 		4 / 8 ASP A  17
THR A  18
LEU A  19
THR A   1
 None
None
None
PO4  A 301 ( 4.5A)
 1.00A 5ov9B-5ovtA:
undetectable		 5ov9B-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5ovt BPH
(Thiobacillus
denitrificans) 		3 / 3 HIS A 174
SER A 177
LYS A   1
 None
None
PO4  A 301 ( 4.1A)
 1.49A 6gmdB-5ovtA:
undetectable		 6gmdB-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.39A 6hwdV-5ovtA:
19.6
6hwdb-5ovtA:
4.0		 6hwdV-5ovtA:
26.51
6hwdb-5ovtA:
28.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5ovt BPH
(Thiobacillus
denitrificans) 		5 / 12 THR A   1
THR A  20
LYS A  37
GLY A  50
ALA A  52
 PO4  A 301 ( 4.5A)
None
None
PO4  A 301 (-4.1A)
None
 0.39A 6hwdH-5ovtA:
5.0
6hwdN-5ovtA:
5.8		 6hwdH-5ovtA:
26.51
6hwdN-5ovtA:
28.74