SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ovu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		5 / 12 LEU A  87
LEU A  60
MET A  57
VAL A  40
VAL A 121
 None
 1.13A 1hrkA-5ovuA:
undetectable		 1hrkA-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		5 / 12 LEU A  87
LEU A  60
MET A  57
VAL A  40
VAL A 121
 None
 1.10A 1hrkB-5ovuA:
undetectable		 1hrkB-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 4 ALA A 162
VAL A   6
ALA A  13
HIS A 183
 None
 1.12A 1q23A-5ovuA:
undetectable		 1q23A-5ovuA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		5 / 12 LEU A  87
LEU A  60
MET A  57
VAL A  40
VAL A 121
 None
 1.13A 2hrcB-5ovuA:
undetectable		 2hrcB-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		5 / 12 LEU A  87
LEU A  60
MET A  57
VAL A  40
VAL A 121
 None
 1.14A 3aqiB-5ovuA:
undetectable		 3aqiB-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 8 PHE A  80
GLU A 126
SER A 123
VAL A 109
 None
 1.29A 3jx1A-5ovuA:
undetectable
3jx1B-5ovuA:
undetectable		 3jx1A-5ovuA:
10.29
3jx1B-5ovuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		5 / 11 THR A   1
THR A  21
LYS A  36
GLY A  49
SER A 138
 None
 0.95A 3mg0K-5ovuA:
16.4
3mg0L-5ovuA:
14.4		 3mg0K-5ovuA:
21.32
3mg0L-5ovuA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 7 PHE A  80
GLU A 126
SER A 123
VAL A 109
 None
 1.24A 3n61A-5ovuA:
undetectable
3n61B-5ovuA:
undetectable		 3n61A-5ovuA:
10.29
3n61B-5ovuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 8 PHE A  80
GLU A 126
SER A 123
VAL A 109
 None
 1.27A 3nlyA-5ovuA:
undetectable
3nlyB-5ovuA:
undetectable		 3nlyA-5ovuA:
10.29
3nlyB-5ovuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 8 PHE A  80
GLU A 126
SER A 123
VAL A 109
 None
 1.25A 3rqlA-5ovuA:
undetectable
3rqlB-5ovuA:
undetectable		 3rqlA-5ovuA:
10.29
3rqlB-5ovuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		5 / 12 LEU A  87
LEU A  60
MET A  57
VAL A  40
VAL A 121
 None
 1.13A 3w1wA-5ovuA:
undetectable		 3w1wA-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 8 PHE A  80
GLU A 126
SER A 123
VAL A 109
 None
 1.29A 4capA-5ovuA:
undetectable
4capB-5ovuA:
undetectable		 4capA-5ovuA:
10.29
4capB-5ovuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 8 PHE A  80
GLU A 126
SER A 123
VAL A 109
 None
 1.30A 4d32A-5ovuA:
undetectable
4d32B-5ovuA:
undetectable		 4d32A-5ovuA:
10.29
4d32B-5ovuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		5 / 12 LEU A  47
GLY A  46
ARG A  58
ILE A 118
VAL A  12
 None
 1.15A 4ok1A-5ovuA:
undetectable		 4ok1A-5ovuA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		5 / 12 LEU A  47
GLY A  46
ARG A  58
ILE A 118
VAL A  12
 None
 1.16A 4okwA-5ovuA:
undetectable		 4okwA-5ovuA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 8 PHE A  80
GLU A 126
SER A 123
VAL A 109
 None
 1.28A 4v3yA-5ovuA:
undetectable
4v3yB-5ovuA:
undetectable		 4v3yA-5ovuA:
10.29
4v3yB-5ovuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 5 VAL A  45
VAL A 121
GLY A 120
PHE A  80
 None
None
MLI  A 202 ( 3.7A)
None
 1.10A 5d4nA-5ovuA:
undetectable
5d4nC-5ovuA:
undetectable		 5d4nA-5ovuA:
undetectable
5d4nC-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		4 / 7 VAL A  76
THR A  79
MET A  64
VAL A  40
 None
 1.04A 5e4dA-5ovuA:
undetectable
5e4dB-5ovuA:
undetectable		 5e4dA-5ovuA:
undetectable
5e4dB-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		3 / 3 ARG A  29
LYS A  32
ARG A 163
 None
 1.33A 6c06D-5ovuA:
undetectable		 6c06D-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE
(Cupriavidus
metallidurans) 		5 / 10 ILE A 118
ASN A 114
LEU A  70
LEU A 111
GLY A 120
 None
None
None
None
MLI  A 202 ( 3.7A)
 1.48A 6r2eC-5ovuA:
undetectable		 6r2eC-5ovuA:
undetectable