SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ovy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 5ovy PUTATIVE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Mycobacteroides
abscessus) 		3 / 3 ARG B 197
ARG B 148
PRO B 149
 None
 1.01A 2wljA-5ovyB:
undetectable		 2wljA-5ovyB:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 5ovy PUTATIVE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Mycobacteroides
abscessus) 		3 / 3 ASP B 155
PHE B 158
LEU B 162
 None
 0.65A 2zi9A-5ovyB:
undetectable		 2zi9A-5ovyB:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 5ovy PUTATIVE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Mycobacteroides
abscessus) 		3 / 3 ARG B 179
ASP B 176
TRP B 178
 None
 1.19A 4xdqA-5ovyB:
undetectable		 4xdqA-5ovyB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 5ovy PUTATIVE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Mycobacteroides
abscessus) 		4 / 6 GLY B  91
ASN B  87
ILE B 186
TRP B  89
 None
 1.16A 5j4nA-5ovyB:
undetectable		 5j4nA-5ovyB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 5ovy PUTATIVE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Mycobacteroides
abscessus) 		4 / 6 GLU B 150
LEU B 147
ARG B 191
ARG B 148
 None
 1.00A 5l6eA-5ovyB:
undetectable
5l6eB-5ovyB:
undetectable		 5l6eA-5ovyB:
undetectable
5l6eB-5ovyB:
undetectable