SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ow6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5ow6 VP1
(Cucumber
mosaic
virus) 		3 / 3 ASP A 191
PHE A 117
VAL A 121
 None
 0.70A 1kijB-5ow6A:
undetectable		 1kijB-5ow6A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J1G_F_SC2F1290_1
(FICOLIN-2)		 5ow6 VP1
(Cucumber
mosaic
virus) 		5 / 10 LEU A 199
SER A 119
LEU A 194
ASP A 192
ASP A 118
 None
 1.36A 2j1gE-5ow6A:
undetectable
2j1gF-5ow6A:
undetectable		 2j1gE-5ow6A:
23.35
2j1gF-5ow6A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 5ow6 VP1
(Cucumber
mosaic
virus) 		4 / 8 MET A 180
LEU A  92
SER A 132
VAL A 125
 None
 1.03A 2qd2A-5ow6A:
undetectable		 2qd2A-5ow6A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 5ow6 CAPSID PROTEIN, VP2
(Cucumber
mosaic
virus) 		5 / 11 PRO B  77
PRO B  78
GLY B  87
LEU B 201
VAL B 185
 None
 1.48A 2uvnB-5ow6B:
undetectable		 2uvnB-5ow6B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 5ow6 VP1
(Cucumber
mosaic
virus) 		5 / 12 GLY A  87
SER A 135
VAL A 121
PRO A  77
LEU A 199
 None
 1.18A 3v8vA-5ow6A:
undetectable		 3v8vA-5ow6A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5ow6 VP1
(Cucumber
mosaic
virus) 		5 / 12 TYR A  99
ILE A 177
VAL A  96
ILE A  73
ILE A 205
 None
 1.24A 3vrjA-5ow6A:
undetectable
3vrjC-5ow6A:
undetectable		 3vrjA-5ow6A:
21.96
3vrjC-5ow6A:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 5ow6 VP1
(Cucumber
mosaic
virus) 		3 / 3 LEU A  91
ARG A 181
ARG A  89
 None
 0.82A 4yiaB-5ow6A:
undetectable		 4yiaB-5ow6A:
12.08