SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5owg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 5owg PCYX_EBK42635
(marine
metagenome) 		3 / 3 TRP A  39
ALA A  68
VAL A  57
 None
 0.86A 1c4dC-5owgA:
undetectable
1c4dD-5owgA:
undetectable		 1c4dC-5owgA:
12.00
1c4dD-5owgA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5owg PCYX_EBK42635
(marine
metagenome) 		5 / 9 CYH A  71
LEU A  70
LEU A 165
ILE A 172
ILE A  82
 None
 1.46A 1hzeA-5owgA:
undetectable
1hzeB-5owgA:
undetectable		 1hzeA-5owgA:
14.75
1hzeB-5owgA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5owg PCYX_EBK42635
(marine
metagenome) 		5 / 9 ILE A  82
CYH A  71
LEU A  70
LEU A 165
ILE A 172
 None
 1.46A 1hzeA-5owgA:
undetectable
1hzeB-5owgA:
undetectable		 1hzeA-5owgA:
14.75
1hzeB-5owgA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5owg PCYX_EBK42635
(marine
metagenome) 		5 / 10 CYH A  71
LEU A  70
LEU A 165
ILE A 172
PHE A 224
 None
 1.09A 1i18A-5owgA:
undetectable
1i18B-5owgA:
undetectable		 1i18A-5owgA:
14.75
1i18B-5owgA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5owg PCYX_EBK42635
(marine
metagenome) 		5 / 10 PHE A 224
CYH A  71
LEU A  70
LEU A 165
ILE A 172
 None
 1.11A 1i18A-5owgA:
undetectable
1i18B-5owgA:
undetectable		 1i18A-5owgA:
14.75
1i18B-5owgA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 5owg PCYX_EBK42635
(marine
metagenome) 		5 / 11 LEU A  54
ALA A  68
LEU A  70
LEU A   6
THR A  13
 None
 1.30A 1tz8A-5owgA:
undetectable
1tz8B-5owgA:
undetectable		 1tz8A-5owgA:
19.01
1tz8B-5owgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 5 ARG A  51
PHE A 218
LEU A 223
PHE A 224
 None
 1.21A 2y69C-5owgA:
undetectable
2y69J-5owgA:
undetectable		 2y69C-5owgA:
21.13
2y69J-5owgA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 5 ARG A  51
PHE A 218
LEU A 223
PHE A 224
 None
 1.22A 2y69P-5owgA:
undetectable
2y69W-5owgA:
undetectable		 2y69P-5owgA:
21.13
2y69W-5owgA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 5 ARG A  51
PHE A 218
LEU A 223
PHE A 224
 None
 1.21A 3abmC-5owgA:
undetectable
3abmJ-5owgA:
undetectable		 3abmC-5owgA:
21.13
3abmJ-5owgA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 5 ARG A  51
PHE A 218
LEU A 223
PHE A 224
 None
 1.14A 3abmP-5owgA:
undetectable
3abmW-5owgA:
undetectable		 3abmP-5owgA:
21.13
3abmW-5owgA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 5 ARG A  51
PHE A 218
LEU A 223
PHE A 224
 None
 1.22A 3ag3C-5owgA:
undetectable
3ag3J-5owgA:
undetectable		 3ag3C-5owgA:
21.13
3ag3J-5owgA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 4 PRO A 110
LEU A 111
ILE A 172
ARG A 173
 None
 1.33A 3w1wA-5owgA:
undetectable		 3w1wA-5owgA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 7 GLU A  12
THR A  13
LEU A 154
SER A 163
 None
 1.03A 4pfjA-5owgA:
undetectable		 4pfjA-5owgA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 5owg PCYX_EBK42635
(marine
metagenome) 		3 / 3 GLU A 176
ARG A  47
TYR A  48
 None
 0.60A 5trqB-5owgA:
undetectable		 5trqB-5owgA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 5 ARG A  51
PHE A 218
LEU A 223
PHE A 224
 None
 1.22A 5wauC-5owgA:
undetectable
5wauJ-5owgA:
undetectable		 5wauC-5owgA:
21.13
5wauJ-5owgA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 5 ARG A  51
PHE A 218
LEU A 223
PHE A 224
 None
 1.22A 5wauc-5owgA:
undetectable
5wauj-5owgA:
undetectable		 5wauc-5owgA:
21.13
5wauj-5owgA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 5 ARG A  51
PHE A 218
LEU A 223
PHE A 224
 None
 1.23A 5xdqC-5owgA:
undetectable
5xdqJ-5owgA:
undetectable		 5xdqC-5owgA:
21.13
5xdqJ-5owgA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5owg PCYX_EBK42635
(marine
metagenome) 		4 / 5 ARG A  51
PHE A 218
LEU A 223
PHE A 224
 None
 1.19A 5xdqP-5owgA:
undetectable
5xdqW-5owgA:
undetectable		 5xdqP-5owgA:
21.13
5xdqW-5owgA:
15.69