SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5owj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 5owj TRIGGER FACTOR
(Escherichia
coli) 		3 / 3 ARG A 271
THR A 133
VAL A 132
 None
 1.01A 1hxbA-5owjA:
undetectable		 1hxbA-5owjA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5owj TRIGGER FACTOR
(Escherichia
coli) 		3 / 3 ARG A 271
THR A 133
VAL A 132
 None
 0.95A 2qakA-5owjA:
undetectable		 2qakA-5owjA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 5owj TRIGGER FACTOR
(Escherichia
coli) 		4 / 5 VAL A 258
GLN A 191
PHE A 252
ARG A 193
 None
 1.27A 3bjwE-5owjA:
undetectable		 3bjwE-5owjA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 5owj TRIGGER FACTOR
(Escherichia
coli) 		4 / 5 VAL A 258
GLN A 191
PHE A 252
ARG A 193
 None
 1.15A 3bjwH-5owjA:
undetectable		 3bjwH-5owjA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 5owj TRIGGER FACTOR
(Escherichia
coli) 		4 / 5 VAL A 258
GLN A 191
PHE A 252
ARG A 193
 None
 1.20A 3bjwB-5owjA:
undetectable		 3bjwB-5owjA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5owj TRIGGER FACTOR
(Escherichia
coli) 		3 / 3 THR A 422
VAL A 130
GLU A 126
 None
 0.75A 3v4tA-5owjA:
undetectable
3v4tD-5owjA:
undetectable		 3v4tA-5owjA:
23.61
3v4tD-5owjA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 5owj TRIGGER FACTOR
(Escherichia
coli) 		4 / 8 ILE A  24
ILE A  17
MET A  71
GLY A  68
 None
 0.87A 4hdlA-5owjA:
undetectable		 4hdlA-5owjA:
11.89