SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5owo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 5owo CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		5 / 11 ILE A 125
LEU A  30
LEU A  37
MET A  65
LEU A 116
 None
 1.04A 1dtlA-5owoA:
undetectable		 1dtlA-5owoA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 5owo CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 8 ALA A  55
GLU A  53
LEU A  37
VAL A  38
 None
 0.92A 2bxgA-5owoA:
2.2		 2bxgA-5owoA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 5owo CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		3 / 3 GLU A  80
GLY A 110
SER A  82
 None
 0.65A 4b53B-5owoA:
undetectable		 4b53B-5owoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 5owo CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 7 LEU A  56
SER A  60
VAL A  27
PHE A  68
 None
 0.87A 4wnvD-5owoA:
undetectable		 4wnvD-5owoA:
undetectable