SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oy0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		3 / 3 ALA 1 380
VAL 1 520
TRP 1 618
 None
 0.92A 1bdwA-5oy01:
undetectable
1bdwB-5oy01:
undetectable		 1bdwA-5oy01:
undetectable
1bdwB-5oy01:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 8 MET b 129
PHE b 124
THR b  61
LEU b 142
 ECH  b1847 (-3.7A)
ECH  b1847 (-4.5A)
CLA  b1831 ( 3.3A)
ECH  b1847 ( 4.4A)
 1.21A 1ea1A-5oy0b:
undetectable		 1ea1A-5oy0b:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 TRP b 579
ASN b 582
LEU b 432
GLY b 428
TYR b 435
 None
None
CLA  b1806 (-4.3A)
None
CLA  b1806 ( 4.4A)
 1.05A 1hvyA-5oy0b:
undetectable		 1hvyA-5oy0b:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 TRP b 579
ASN b 582
LEU b 432
GLY b 428
TYR b 435
 None
None
CLA  b1806 (-4.3A)
None
CLA  b1806 ( 4.4A)
 1.08A 1hvyB-5oy0b:
undetectable		 1hvyB-5oy0b:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 11 TRP b 579
ASN b 582
LEU b 432
GLY b 428
TYR b 435
 None
None
CLA  b1806 (-4.3A)
None
CLA  b1806 ( 4.4A)
 1.08A 1hvyC-5oy0b:
undetectable		 1hvyC-5oy0b:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 TRP b 579
ASN b 582
LEU b 432
GLY b 428
TYR b 435
 None
None
CLA  b1806 (-4.3A)
None
CLA  b1806 ( 4.4A)
 0.98A 1hvyD-5oy0b:
undetectable		 1hvyD-5oy0b:
15.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		9 / 9 MET 1 684
PHE 1 685
SER 1 688
GLY 1 689
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 4.3A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.32A 1jb0A-5oy01:
47.1		 1jb0A-5oy01:
85.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.60A 1jb0A-5oy0b:
34.8		 1jb0A-5oy0b:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		9 / 11 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ILE 1 697
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
None
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.44A 1jb0B-5oy01:
33.9		 1jb0B-5oy01:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		11 / 11 TRP b  22
MET b 659
PHE b 660
SER b 663
TRP b 664
ARG b 665
TRP b 668
ILE b 672
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
CLA  b1841 (-4.6A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.36A 1jb0B-5oy0b:
44.4		 1jb0B-5oy0b:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		3 / 3 ALA b 708
HIS b 709
VAL b 712
 CLA  b1842 ( 3.9A)
CLA  b1842 (-3.9A)
LMG  b1851 (-4.5A)
 0.37A 1lqtB-5oy0b:
undetectable		 1lqtB-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		3 / 3 ALA b 708
HIS b 709
VAL b 712
 CLA  b1842 ( 3.9A)
CLA  b1842 (-3.9A)
LMG  b1851 (-4.5A)
 0.38A 1lquB-5oy0b:
undetectable		 1lquB-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS b 387
ALA b 386
PHE b 385
GLY b 333
 CLA  b1832 (-3.9A)
CLA  b1832 ( 3.9A)
BCR  b1848 ( 3.3A)
BCR  b1848 ( 4.4A)
 1.11A 1mj2D-5oy0b:
undetectable		 1mj2D-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS b 387
ALA b 386
PHE b 385
GLY b 333
 CLA  b1832 (-3.9A)
CLA  b1832 ( 3.9A)
BCR  b1848 ( 3.3A)
BCR  b1848 ( 4.4A)
 1.14A 1mjoA-5oy0b:
undetectable		 1mjoA-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 5 LEU b 515
TRP b 593
LEU b 613
GLN b 450
 None
None
CLA  b1806 (-4.7A)
None
 1.29A 1p93D-5oy0b:
undetectable		 1p93D-5oy0b:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY 1 408
HIS 1 407
SER 1  69
ASP 1 415
VAL 1 553
 BCR  1 847 (-3.6A)
CLA  1 830 (-3.9A)
CLA  1 825 ( 4.1A)
None
BCR  1 848 (-4.8A)
 1.29A 1qu3A-5oy01:
undetectable		 1qu3A-5oy01:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		3 / 3 TRP b 593
THR b 611
TYR b 612
 None
 1.14A 2a3aA-5oy0b:
undetectable		 2a3aA-5oy0b:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		3 / 3 TRP b 593
THR b 611
TYR b 612
 None
 1.14A 2a3aB-5oy0b:
undetectable		 2a3aB-5oy0b:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		3 / 3 TRP b 593
THR b 611
TYR b 612
 None
 1.13A 2a3bA-5oy0b:
undetectable		 2a3bA-5oy0b:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		6 / 8 MET 1 684
PHE 1 685
SER 1 688
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 1.00A 2o01A-5oy01:
35.0		 2o01A-5oy01:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 8 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 3.6A)
 1.15A 2o01A-5oy01:
35.0		 2o01A-5oy01:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 8 MET b 659
PHE b 660
SER b 663
TRP b 668
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
PQN  b1844 ( 3.4A)
PQN  b1844 ( 3.8A)
 1.15A 2o01A-5oy0b:
29.0		 2o01A-5oy0b:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 8 MET b 659
SER b 663
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 1.08A 2o01A-5oy0b:
29.0		 2o01A-5oy0b:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		6 / 9 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
 0.77A 2o01B-5oy01:
23.4		 2o01B-5oy01:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		6 / 9 MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.83A 2o01B-5oy01:
23.4		 2o01B-5oy01:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		8 / 9 MET b 659
PHE b 660
SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
ALA b 702
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 (-3.1A)
 0.80A 2o01B-5oy0b:
29.9		 2o01B-5oy0b:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		8 / 9 PHE b 660
SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.74A 2o01B-5oy0b:
29.9		 2o01B-5oy0b:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 9 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.71A 2wscA-5oy01:
14.7		 2wscA-5oy01:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		6 / 9 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
LEU 1 718
GLY 1 723
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 1.46A 2wscA-5oy01:
14.7		 2wscA-5oy01:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.80A 2wscA-5oy0b:
28.8		 2wscA-5oy0b:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 10 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.73A 2wscB-5oy01:
11.4		 2wscB-5oy01:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 10 SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 1.40A 2wscB-5oy0b:
19.7		 2wscB-5oy0b:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 10 TRP b  22
MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.83A 2wscB-5oy0b:
19.7		 2wscB-5oy0b:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 9 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.70A 2wseA-5oy01:
14.8		 2wseA-5oy01:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		6 / 9 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
LEU 1 718
GLY 1 723
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 1.45A 2wseA-5oy01:
14.8		 2wseA-5oy01:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.80A 2wseA-5oy0b:
13.2		 2wseA-5oy0b:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		6 / 9 TRP b  22
MET b 659
PHE b 660
SER b 663
TRP b 668
LEU b 697
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
PQN  b1844 ( 3.4A)
PQN  b1844 ( 3.8A)
 1.49A 2wseA-5oy0b:
13.2		 2wseA-5oy0b:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 10 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.72A 2wseB-5oy01:
11.6		 2wseB-5oy01:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 10 SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 1.39A 2wseB-5oy0b:
19.7		 2wseB-5oy0b:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 10 TRP b  22
MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.82A 2wseB-5oy0b:
19.7		 2wseB-5oy0b:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 9 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.67A 2wsfA-5oy01:
7.6		 2wsfA-5oy01:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		6 / 9 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
LEU 1 718
GLY 1 723
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 1.44A 2wsfA-5oy01:
7.6		 2wsfA-5oy01:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.78A 2wsfA-5oy0b:
29.8		 2wsfA-5oy0b:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		6 / 9 TRP b  22
MET b 659
PHE b 660
SER b 663
TRP b 668
LEU b 697
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
PQN  b1844 ( 3.4A)
PQN  b1844 ( 3.8A)
 1.48A 2wsfA-5oy0b:
29.8		 2wsfA-5oy0b:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.66A 2wsfB-5oy01:
12.3		 2wsfB-5oy01:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		8 / 9 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.82A 2wsfB-5oy0b:
12.1		 2wsfB-5oy0b:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		6 / 9 TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 1.45A 2wsfB-5oy0b:
12.1		 2wsfB-5oy0b:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL 1 678
PHE 1 742
SER 1 610
VAL 1 737
TYR 1 599
 BCR  1 856 (-4.9A)
CLA  1 801 (-3.4A)
None
BCR  1 856 (-3.7A)
CLA  1 801 (-4.5A)
 1.25A 2y01A-5oy01:
undetectable		 2y01A-5oy01:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT II
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR 4  33
ILE 4  80
TYR 4  83
PHE 4 104
ARG 4  73
 None
 1.31A 2y7kC-5oy04:
undetectable		 2y7kC-5oy04:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT II
(Synechocystis
sp.
PCC
6803) 		5 / 9 THR 4  33
ILE 4  80
TYR 4  83
PHE 4 104
ARG 4  73
 None
 1.44A 2y7wA-5oy04:
undetectable		 2y7wA-5oy04:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		4 / 4 GLY 0 134
GLY 0 131
GLY 0  54
GLY 0  58
 BCR  0 205 ( 4.0A)
None
None
None
 0.66A 3bogC-5oy00:
undetectable		 3bogC-5oy00:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		4 / 4 GLY 0 134
GLY 0 131
GLY 0  54
GLY 0  58
 BCR  0 205 ( 4.0A)
None
None
None
 0.64A 3bogD-5oy00:
undetectable		 3bogD-5oy00:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU 0 141
LEU 0 142
GLN 0  77
LEU 0  67
TYR 0  59
 CLA  0 203 ( 4.2A)
CLA  0 203 (-4.6A)
None
CLA  0 203 (-4.1A)
BCR  0 205 (-4.0A)
 1.29A 3d90B-5oy00:
undetectable		 3d90B-5oy00:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 11 LEU b 628
LEU b 640
GLY b 650
HIS b 651
LEU b 648
 None
None
None
CLA  b1806 ( 4.0A)
None
 1.05A 3hm1B-5oy0b:
undetectable		 3hm1B-5oy0b:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE 0 127
GLY 0  54
ALA 0  87
GLY 0  58
LEU 0  61
 BCR  0 204 (-4.0A)
None
None
None
None
 0.97A 3hs6B-5oy00:
1.2		 3hs6B-5oy00:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 9 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.67A 3lw5A-5oy01:
38.1		 3lw5A-5oy01:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		6 / 9 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
LEU 1 718
GLY 1 723
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 1.34A 3lw5A-5oy01:
38.1		 3lw5A-5oy01:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.76A 3lw5A-5oy0b:
11.7		 3lw5A-5oy0b:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		6 / 9 TRP b  22
MET b 659
PHE b 660
SER b 663
TRP b 668
LEU b 697
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
PQN  b1844 ( 3.4A)
PQN  b1844 ( 3.8A)
 1.38A 3lw5A-5oy0b:
11.7		 3lw5A-5oy0b:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 10 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.64A 3lw5B-5oy01:
11.2		 3lw5B-5oy01:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 10 ILE b  21
MET b 659
PHE b 660
SER b 663
ALA b 702
 None
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
PQN  b1844 (-3.1A)
 1.33A 3lw5B-5oy0b:
12.1		 3lw5B-5oy0b:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 10 ILE b  25
MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 LMG  b1851 ( 4.9A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.81A 3lw5B-5oy0b:
12.1		 3lw5B-5oy0b:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		6 / 10 TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 1.44A 3lw5B-5oy0b:
12.1		 3lw5B-5oy0b:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 TRP b 579
ASN b 582
LEU b 432
GLY b 428
TYR b 435
 None
None
CLA  b1806 (-4.3A)
None
CLA  b1806 ( 4.4A)
 1.06A 3nrrA-5oy0b:
undetectable		 3nrrA-5oy0b:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 TRP b 579
ASN b 582
LEU b 432
GLY b 428
TYR b 435
 None
None
CLA  b1806 (-4.3A)
None
CLA  b1806 ( 4.4A)
 1.06A 3nrrB-5oy0b:
undetectable		 3nrrB-5oy0b:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 11 PHE b 647
HIS b 651
LEU b 628
ILE b 629
SER b 625
 CLA  b1806 (-4.7A)
CLA  b1806 ( 4.0A)
None
CLA  b1806 ( 4.7A)
CLA  b1806 (-3.6A)
 1.47A 3o94C-5oy0b:
undetectable		 3o94C-5oy0b:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		9 / 9 MET 1 684
PHE 1 685
SER 1 688
GLY 1 689
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 4.3A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.34A 3pcqA-5oy01:
47.1		 3pcqA-5oy01:
85.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.61A 3pcqA-5oy0b:
34.8		 3pcqA-5oy0b:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		9 / 11 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ILE 1 697
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
None
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.44A 3pcqB-5oy01:
33.9		 3pcqB-5oy01:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		11 / 11 TRP b  22
MET b 659
PHE b 660
SER b 663
TRP b 664
ARG b 665
TRP b 668
ILE b 672
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
CLA  b1841 (-4.6A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.36A 3pcqB-5oy0b:
44.5		 3pcqB-5oy0b:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU b 628
LEU b 640
GLY b 650
HIS b 651
LEU b 648
 None
None
None
CLA  b1806 ( 4.0A)
None
 0.99A 3q95B-5oy0b:
undetectable		 3q95B-5oy0b:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE b 244
PHE b 358
THR b 126
LEU b 270
 None
None
CLA  b1821 ( 4.7A)
None
 0.92A 3t3sC-5oy0b:
undetectable		 3t3sC-5oy0b:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		3 / 3 SER b   9
PHE b   5
LYS b   3
 None
 0.73A 3u88A-5oy0b:
0.0		 3u88A-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 8 LEU b 369
HIS b  89
TYR b 117
HIS b  67
 CLA  b1831 ( 4.4A)
CLA  b1811 ( 3.9A)
CLA  b1811 ( 4.5A)
CLA  b1810 (-3.9A)
 1.14A 3x2qC-5oy0b:
1.9
3x2qN-5oy0b:
undetectable
3x2qP-5oy0b:
1.9		 3x2qC-5oy0b:
undetectable
3x2qN-5oy0b:
undetectable
3x2qP-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		4 / 6 HIS 1 590
GLY 1 587
TYR 1 555
ALA 1 409
 None
 0.92A 4ae1A-5oy01:
undetectable		 4ae1A-5oy01:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		4 / 6 VAL 1 443
LEU 1 440
ILE 1 445
CYH 1 444
 CLA  1 838 (-4.9A)
CLA  1 838 (-3.5A)
CLA  1 832 (-4.1A)
None
 0.93A 4asdA-5oy01:
undetectable		 4asdA-5oy01:
14.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 10 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.40A 4fe1A-5oy01:
46.5
4fe1J-5oy01:
undetectable		 4fe1A-5oy01:
85.00
4fe1J-5oy01:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 10 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.62A 4fe1A-5oy0b:
34.6
4fe1J-5oy0b:
undetectable		 4fe1A-5oy0b:
7.11
4fe1J-5oy0b:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ILE 1 697
ALA 1 717
LEU 1 718
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
None
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.44A 4fe1B-5oy01:
33.7		 4fe1B-5oy01:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 9 MET b 659
SER b 663
TRP b 664
ARG b 665
TRP b 668
ILE b 672
ALA b 696
LEU b 697
ALA b 702
 CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
CLA  b1841 (-4.6A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.38A 4fe1B-5oy0b:
43.9		 4fe1B-5oy0b:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU b 476
ASP b 272
ALA b 488
TRP b 494
GLY b 259
 CLA  b1836 (-4.3A)
None
CLA  b1837 ( 4.1A)
CLA  b1836 ( 4.1A)
CLA  b1820 ( 4.0A)
 1.14A 4hfpD-5oy0b:
undetectable		 4hfpD-5oy0b:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE b 520
TYR b 620
PHE b 721
TYR b 718
TRP b 599
 CLA  b1838 (-4.1A)
None
CLA  b1806 (-3.2A)
CLA  b1806 (-4.6A)
None
 1.24A 4j03A-5oy0b:
undetectable		 4j03A-5oy0b:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		3 / 3 TYR b 590
GLN b 374
TRP b 586
 CLA  b1838 (-3.8A)
CLA  b1828 (-3.2A)
CLA  b1806 ( 3.6A)
 1.13A 4kn2C-5oy0b:
undetectable		 4kn2C-5oy0b:
16.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		9 / 11 MET 1 684
PHE 1 685
SER 1 688
GLY 1 689
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 4.3A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.40A 4kt0A-5oy01:
46.6
4kt0J-5oy01:
undetectable		 4kt0A-5oy01:
100.00
4kt0J-5oy01:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 11 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.61A 4kt0A-5oy0b:
34.4
4kt0J-5oy0b:
undetectable		 4kt0A-5oy0b:
7.36
4kt0J-5oy0b:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 TRP 1  49
MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.50A 4kt0B-5oy01:
35.6		 4kt0B-5oy01:
7.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KT0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 9 TRP b  22
MET b 659
SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.34A 4kt0B-5oy0b:
44.9		 4kt0B-5oy0b:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		10 / 11 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
GLY 1 689
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 4.3A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.43A 4l6v1-5oy01:
45.9
4l6v6-5oy01:
1.9		 4l6v1-5oy01:
100.00
4l6v6-5oy01:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		8 / 11 TRP b  22
MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.60A 4l6v1-5oy0b:
34.5
4l6v6-5oy0b:
undetectable		 4l6v1-5oy0b:
7.36
4l6v6-5oy0b:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 TRP 1  49
MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.52A 4l6v2-5oy01:
40.2		 4l6v2-5oy01:
7.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 9 TRP b  22
MET b 659
SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.52A 4l6v2-5oy0b:
44.9		 4l6v2-5oy0b:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 9 TRP 1  49
MET 1 684
PHE 1 685
SER 1 688
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.33A 4l6va-5oy01:
45.4
4l6vf-5oy01:
0.1		 4l6va-5oy01:
100.00
4l6vf-5oy01:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 TRP b  22
MET b 659
PHE b 660
SER b 663
TRP b 668
ALA b 696
LEU b 697
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.51A 4l6va-5oy0b:
34.4
4l6vf-5oy0b:
undetectable		 4l6va-5oy0b:
7.36
4l6vf-5oy0b:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 TRP 1  49
MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.47A 4l6vB-5oy01:
34.1		 4l6vB-5oy01:
7.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 9 TRP b  22
MET b 659
SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.51A 4l6vB-5oy0b:
44.7		 4l6vB-5oy0b:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY 0 133
GLY 0 131
GLY 0 130
LEU 0  51
GLY 0  58
 BCR  0 205 (-3.5A)
None
None
CLA  0 201 ( 4.8A)
None
 0.90A 4o33A-5oy00:
undetectable		 4o33A-5oy00:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY 0 133
GLY 0 131
GLY 0 130
LEU 0  51
GLY 0  58
 BCR  0 205 (-3.5A)
None
None
CLA  0 201 ( 4.8A)
None
 0.75A 4o3fA-5oy00:
undetectable		 4o3fA-5oy00:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 SER 1 615
PHE 1 635
ASP 1 531
GLY 1 633
ASP 1 616
 None
 1.45A 4pevA-5oy01:
undetectable		 4pevA-5oy01:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 SER 1 615
PHE 1 635
ASP 1 531
GLY 1 633
ASP 1 616
 None
 1.41A 4pevC-5oy01:
undetectable		 4pevC-5oy01:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU b 628
LEU b 640
GLY b 650
HIS b 651
LEU b 648
 None
None
None
CLA  b1806 ( 4.0A)
None
 1.01A 4pxmA-5oy0b:
undetectable		 4pxmA-5oy0b:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 TRP 1  49
MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.50A 4rkuB-5oy01:
34.0		 4rkuB-5oy01:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 9 TRP b  22
MET b 659
SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.46A 4rkuB-5oy0b:
43.5		 4rkuB-5oy0b:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 10 ASP 1 292
ALA 1 503
ILE 1 514
LEU 1 281
TYR 1 507
 None
 1.22A 4xj7A-5oy01:
undetectable
4xj7B-5oy01:
undetectable		 4xj7A-5oy01:
15.89
4xj7B-5oy01:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 7 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.31A 4xk8A-5oy01:
45.1		 4xk8A-5oy01:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 7 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.60A 4xk8A-5oy0b:
34.6		 4xk8A-5oy0b:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 8 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.27A 4xk8a-5oy01:
45.1		 4xk8a-5oy01:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 8 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.59A 4xk8a-5oy0b:
34.6		 4xk8a-5oy0b:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 10 TRP 1  49
MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ILE 1 697
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
None
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.50A 4xk8B-5oy01:
37.3		 4xk8B-5oy01:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		10 / 10 TRP b  22
MET b 659
SER b 663
TRP b 664
ARG b 665
TRP b 668
ILE b 672
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
CLA  b1841 (-4.6A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.40A 4xk8B-5oy0b:
44.7		 4xk8B-5oy0b:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		8 / 9 MET 1 684
PHE 1 685
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.29A 4y28A-5oy01:
44.1
4y28J-5oy01:
undetectable		 4y28A-5oy01:
8.88
4y28J-5oy01:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.62A 4y28A-5oy0b:
34.1
4y28J-5oy0b:
undetectable		 4y28A-5oy0b:
8.28
4y28J-5oy0b:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 TRP 1  49
MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.45A 4y28B-5oy01:
34.3		 4y28B-5oy01:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 9 TRP b  22
MET b 659
SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.36A 4y28B-5oy0b:
44.2		 4y28B-5oy0b:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY 1 405
GLY 1 408
ILE 1 401
LEU 1 549
ALA 1 556
 BCR  1 848 ( 3.9A)
BCR  1 847 (-3.6A)
CLA  1 826 ( 3.7A)
BCR  1 848 (-3.9A)
None
 1.16A 5bw4B-5oy01:
undetectable		 5bw4B-5oy01:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 6 PHE b 141
SER b 147
ALA b 146
LEU b 143
 CLA  b1817 (-4.0A)
None
None
None
 1.13A 5dzkB-5oy0b:
undetectable
5dzkP-5oy0b:
undetectable		 5dzkB-5oy0b:
undetectable
5dzkP-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE b 141
SER b 147
ALA b 146
LEU b 143
 CLA  b1817 (-4.0A)
None
None
None
 1.15A 5dzkD-5oy0b:
undetectable
5dzkR-5oy0b:
undetectable		 5dzkD-5oy0b:
undetectable
5dzkR-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_B_GLYB404_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 4 GLN b  10
ALA b  13
GLN b  14
THR b   3
 None
 1.25A 5hhjB-5oy0b:
undetectable		 5hhjB-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE 0  62
ALA 0 135
GLY 0  69
GLY 0  84
LEU 0  86
 None
None
CLA  1 833 ( 4.2A)
None
None
 1.26A 5i71A-5oy00:
undetectable		 5i71A-5oy00:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		3 / 3 SER b   9
LEU b  42
MET b  37
 None
 0.77A 5ikrB-5oy0b:
undetectable		 5ikrB-5oy0b:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		3 / 3 TYR 1 145
TYR 1 668
SER 1 747
 None
CLA  1 808 (-4.0A)
None
 0.95A 5iktB-5oy01:
undetectable		 5iktB-5oy01:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 8 LEU b 369
HIS b  89
TYR b 117
HIS b  67
 CLA  b1831 ( 4.4A)
CLA  b1811 ( 3.9A)
CLA  b1811 ( 4.5A)
CLA  b1810 (-3.9A)
 1.14A 5iy5C-5oy0b:
1.9
5iy5N-5oy0b:
undetectable
5iy5P-5oy0b:
1.9		 5iy5C-5oy0b:
undetectable
5iy5N-5oy0b:
undetectable
5iy5P-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		9 / 9 MET 1 684
PHE 1 685
SER 1 688
GLY 1 689
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 4.3A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.34A 5l8rA-5oy01:
44.7		 5l8rA-5oy01:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.63A 5l8rA-5oy0b:
34.5		 5l8rA-5oy0b:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_B_PQNB841_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 9 MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ALA 1 717
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
 0.83A 5l8rB-5oy01:
34.7		 5l8rB-5oy01:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_B_PQNB841_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		6 / 9 TRP 1  49
MET 1 684
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.39A 5l8rB-5oy01:
34.7		 5l8rB-5oy01:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_B_PQNB841_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 9 TRP b  22
MET b 659
SER b 663
TRP b 664
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.52A 5l8rB-5oy0b:
44.9		 5l8rB-5oy0b:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 6 TYR b 351
TYR b 370
HIS b 363
TYR b 590
 CLA  b1838 (-4.4A)
None
None
CLA  b1838 (-3.8A)
 1.04A 5ov9A-5oy0b:
undetectable		 5ov9A-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 7 TYR b 351
TYR b 370
HIS b 363
TYR b 590
 CLA  b1838 (-4.4A)
None
None
CLA  b1838 (-3.8A)
 1.10A 5ov9B-5oy0b:
undetectable		 5ov9B-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		4 / 8 VAL 0  53
LEU 0  96
THR 0  93
ALA 0  92
 CLA  0 202 (-3.1A)
BCR  0 204 (-4.0A)
None
BCR  0 204 ( 3.5A)
 0.90A 5tt3H-5oy00:
undetectable		 5tt3H-5oy00:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		4 / 6 ASN 1 424
ASN 1 421
ILE 1 343
GLU 1 342
 None
 1.06A 5uigA-5oy01:
2.6		 5uigA-5oy01:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 5 THR b 502
GLU b 266
THR b 265
HIS b 242
 None
 1.31A 5utuH-5oy0b:
undetectable		 5utuH-5oy0b:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT PSAK 2
(Synechocystis
sp.
PCC
6803) 		4 / 6 PHE k  61
GLY k  45
THR k  44
LYS k  43
 None
 0.75A 5x24A-5oy0k:
undetectable		 5x24A-5oy0k:
10.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGB_B_PQNB844_1
(PSAB)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 ILE 1  48
TRP 1  49
MET 1 684
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 None
CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 1.16A 5zgbB-5oy01:
37.4		 5zgbB-5oy01:
36.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGB_B_PQNB844_1
(PSAB)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		8 / 9 ILE b  21
TRP b  22
MET b 659
TRP b 664
ARG b 665
ALA b 696
LEU b 697
ALA b 702
 None
CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
None
None
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.57A 5zgbB-5oy0b:
42.3		 5zgbB-5oy0b:
89.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGB_B_PQNB844_1
(PSAB)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 9 ILE b  21
TRP b  22
MET b 659
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 None
CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 1.18A 5zgbB-5oy0b:
42.3		 5zgbB-5oy0b:
89.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGB_B_PQNB844_1
(PSAB)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 9 ILE b  25
MET b 659
TRP b 664
LEU b 697
ALA b 702
 LMG  b1851 ( 4.9A)
CLA  b1807 ( 3.2A)
None
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 1.43A 5zgbB-5oy0b:
42.3		 5zgbB-5oy0b:
89.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGH_B_PQNB843_1
(PSAB)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 ILE 1  48
TRP 1  49
MET 1 684
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 None
CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 1.17A 5zghB-5oy01:
33.9		 5zghB-5oy01:
36.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGH_B_PQNB843_1
(PSAB)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		8 / 9 ILE b  21
TRP b  22
MET b 659
TRP b 664
ARG b 665
ALA b 696
LEU b 697
ALA b 702
 None
CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
None
None
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.60A 5zghB-5oy0b:
42.0		 5zghB-5oy0b:
89.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGH_B_PQNB843_1
(PSAB)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		6 / 9 ILE b  21
TRP b  22
MET b 659
TRP b 668
ALA b 696
LEU b 697
 None
CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 1.26A 5zghB-5oy0b:
42.0		 5zghB-5oy0b:
89.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		9 / 10 MET 1 684
PHE 1 685
SER 1 688
GLY 1 689
ARG 1 690
TRP 1 693
ILE 1 697
ALA 1 717
LEU 1 718
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.8A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 4.3A)
None
PQN  1 842 ( 3.3A)
None
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.30A 5zjiA-5oy01:
46.7
5zjiJ-5oy01:
undetectable		 5zjiA-5oy01:
64.94
5zjiJ-5oy01:
21.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		8 / 10 MET b 659
PHE b 660
SER b 663
ARG b 665
TRP b 668
ILE b 672
ALA b 696
LEU b 697
 CLA  b1807 ( 3.2A)
PQN  b1844 ( 4.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
CLA  b1841 (-4.6A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.56A 5zjiA-5oy0b:
34.5
5zjiJ-5oy0b:
undetectable		 5zjiA-5oy0b:
42.62
5zjiJ-5oy0b:
20.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 10 TRP 1  49
MET 1 684
ARG 1 690
TRP 1 693
ILE 1 697
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
None
PQN  1 842 ( 3.3A)
None
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.57A 5zjiB-5oy01:
37.4		 5zjiB-5oy01:
32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		6 / 10 ILE b  21
MET b 659
TRP b 664
TRP b 668
LEU b 697
ALA b 702
 None
CLA  b1807 ( 3.2A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 1.44A 5zjiB-5oy0b:
44.3		 5zjiB-5oy0b:
78.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		10 / 10 TRP b  22
ILE b  25
MET b 659
TRP b 664
ARG b 665
TRP b 668
ILE b 672
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
LMG  b1851 ( 4.9A)
CLA  b1807 ( 3.2A)
None
None
PQN  b1844 ( 3.4A)
CLA  b1841 (-4.6A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.37A 5zjiB-5oy0b:
44.3		 5zjiB-5oy0b:
78.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		4 / 6 GLY 1 142
THR 1 385
GLN 1 386
TYR 1 145
 CLA  1 829 (-4.6A)
None
None
None
 1.08A 6ag0A-5oy01:
undetectable		 6ag0A-5oy01:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		4 / 6 GLY 1 142
THR 1 385
GLN 1 386
TYR 1 145
 CLA  1 829 (-4.6A)
None
None
None
 1.14A 6ag0C-5oy01:
undetectable		 6ag0C-5oy01:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE b 472
ALA b 604
THR b 611
LEU b 452
ILE b 453
 None
None
None
None
C7Z  b1858 ( 4.9A)
 1.15A 6aybA-5oy0b:
undetectable		 6aybA-5oy0b:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 ASP 1 589
SER 1 586
VAL 1 402
GLY 1 405
ALA 1 409
 None
None
CLA  1 830 ( 4.7A)
BCR  1 848 ( 3.9A)
None
 1.12A 6bqgA-5oy01:
1.7		 6bqgA-5oy01:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		3 / 3 SER b 484
SER b 481
ALA b 463
 None
LMG  b1855 (-2.8A)
None
 0.69A 6dwnC-5oy0b:
undetectable		 6dwnC-5oy0b:
14.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		6 / 6 TRP 1  49
MET 1 684
GLY 1 689
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 ( 4.3A)
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.62A 6fosA-5oy01:
41.0		 6fosA-5oy01:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 6 TRP b  22
MET b 659
TRP b 668
ALA b 696
LEU b 697
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.56A 6fosA-5oy0b:
32.2		 6fosA-5oy0b:
33.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT III
(Synechocystis
sp.
PCC
6803) 		4 / 6 GLY F 115
TRP F 118
ALA F 121
LEU F 120
 None
 0.97A 6fosA-5oy0F:
2.1		 6fosA-5oy0F:
20.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 6 MET 1 684
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
 CLA  1 802 ( 3.2A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.76A 6fosB-5oy01:
27.7		 6fosB-5oy01:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		6 / 6 MET b 659
ARG b 665
TRP b 668
ALA b 696
LEU b 697
ALA b 702
 CLA  b1807 ( 3.2A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.60A 6fosB-5oy0b:
32.7		 6fosB-5oy0b:
85.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT II
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY 4  46
VAL 1 422
GLY 1 569
ASP 1 417
GLN 4  71
 None
 1.13A 6gngA-5oy04:
undetectable		 6gngA-5oy04:
9.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		9 / 10 TRP 1  49
MET 1 684
SER 1 688
GLY 1 689
ARG 1 690
TRP 1 693
ALA 1 717
LEU 1 718
GLY 1 723
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
PQN  1 842 ( 4.3A)
None
PQN  1 842 ( 3.3A)
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
PQN  1 842 ( 3.9A)
 0.37A 6hqbA-5oy01:
44.9
6hqbJ-5oy01:
undetectable		 6hqbA-5oy01:
100.00
6hqbJ-5oy01:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		7 / 10 TRP b  22
MET b 659
SER b 663
ARG b 665
TRP b 668
ALA b 696
LEU b 697
 CLA  b1841 ( 4.0A)
CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
 0.64A 6hqbA-5oy0b:
34.0
6hqbJ-5oy0b:
undetectable		 6hqbA-5oy0b:
25.45
6hqbJ-5oy0b:
16.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		7 / 9 MET 1 684
SER 1 688
ARG 1 690
TRP 1 693
ILE 1 697
ALA 1 717
LEU 1 718
 CLA  1 802 ( 3.2A)
PQN  1 842 (-3.4A)
None
PQN  1 842 ( 3.3A)
None
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.40A 6hqbB-5oy01:
34.1		 6hqbB-5oy01:
35.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		9 / 9 MET b 659
SER b 663
TRP b 664
ARG b 665
TRP b 668
ILE b 672
ALA b 696
LEU b 697
ALA b 702
 CLA  b1807 ( 3.2A)
PQN  b1844 (-3.7A)
None
None
PQN  b1844 ( 3.4A)
CLA  b1841 (-4.6A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.37A 6hqbB-5oy0b:
44.1		 6hqbB-5oy0b:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR b 246
ASP b 238
TRP b  77
PHE b 358
TYR b 125
 None
 1.45A 6iblA-5oy0b:
2.5		 6iblA-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR b 246
ASP b 238
TRP b  77
PHE b 358
TYR b 125
 None
 1.44A 6iblB-5oy0b:
2.9		 6iblB-5oy0b:
undetectable