SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5oy9 GLYCOPROTEIN G
(Indiana
vesiculovirus) 		5 / 12 PHE A 237
ILE A 186
LEU A 195
VAL A 229
ALA A 218
 None
 1.03A 1epbA-5oy9A:
undetectable		 1epbA-5oy9A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MSK_A_SAMA1301_0
(COBALAMIN-DEPENDENT
METHIONINE SYNTHASE)		 5oy9 GLYCOPROTEIN G
(Indiana
vesiculovirus) 		5 / 10 ASP A 334
PRO A 307
ALA A 306
PRO A 370
ALA A 315
 None
 1.44A 1mskA-5oy9A:
undetectable		 1mskA-5oy9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_A_478A200_1
(HIV-1 PROTEASE)		 5oy9 GLYCOPROTEIN G
(Indiana
vesiculovirus) 		4 / 6 GLU A 327
PRO A 262
ARG A 329
GLY A 313
 None
None
MLZ  A  50 ( 4.0A)
None
 1.29A 3oxvA-5oy9A:
undetectable		 3oxvA-5oy9A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_A_DAHA351_1
(PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN)		 5oy9 GLYCOPROTEIN G
(Indiana
vesiculovirus) 		5 / 9 SER A 266
GLN A 264
VAL A 235
ALA A 261
GLY A 311
 None
 1.37A 3tehA-5oy9A:
undetectable		 3tehA-5oy9A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 5oy9 GLYCOPROTEIN G
(Indiana
vesiculovirus) 		5 / 9 LEU A 374
ILE A 319
GLY A 321
VAL A 366
ILE A 368
 None
 1.12A 5kr2D-5oy9A:
undetectable		 5kr2D-5oy9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5oy9 GLYCOPROTEIN G
(Indiana
vesiculovirus) 		4 / 8 LEU A 374
GLY A 372
VAL A 300
SER A 303
 None
 0.93A 5m8rC-5oy9A:
undetectable		 5m8rC-5oy9A:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5oy9 GLYCOPROTEIN G
(Indiana
vesiculovirus) 		3 / 3 SER A 260
ALA A 261
THR A 312
 None
 0.67A 5n0xB-5oy9A:
undetectable		 5n0xB-5oy9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5oy9 GLYCOPROTEIN G
LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens;
Indiana
vesiculovirus) 		4 / 5 ASP A 334
GLU D 119
ARG A 354
THR A 352
 None
CA  D1001 (-2.9A)
None
None
 0.87A 5uxcA-5oy9A:
undetectable		 5uxcA-5oy9A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 5oy9 GLYCOPROTEIN G
(Indiana
vesiculovirus) 		5 / 11 ASP A 334
PRO A 307
ALA A 306
PRO A 370
ALA A 315
 None
 1.42A 6bm5A-5oy9A:
undetectable		 6bm5A-5oy9A:
undetectable