SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oyd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 8 PHE A 372
ILE A 368
LEU A 388
VAL A 418
 None
 0.82A 1fslB-5oydA:
undetectable		 1fslB-5oydA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.51A 1jnoA-5oydA:
undetectable		 1jnoA-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.51A 1jnoB-5oydA:
undetectable		 1jnoB-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.66A 1jo3A-5oydA:
undetectable		 1jo3A-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.66A 1jo3B-5oydA:
undetectable		 1jo3B-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.68A 1jo4A-5oydA:
undetectable		 1jo4A-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.68A 1jo4B-5oydA:
undetectable		 1jo4B-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ARG A 395
ARG A 447
ARG A 411
 None
 1.10A 1l7fA-5oydA:
undetectable		 1l7fA-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.60A 1magA-5oydA:
undetectable		 1magA-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.60A 1magB-5oydA:
undetectable		 1magB-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.52A 1ng8A-5oydA:
undetectable		 1ng8A-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.52A 1ng8B-5oydA:
undetectable		 1ng8B-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.71A 1nrmA-5oydA:
undetectable		 1nrmA-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.71A 1nrmB-5oydA:
undetectable		 1nrmB-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.58A 1nruA-5oydA:
undetectable		 1nruA-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ALA A 136
VAL A 168
TRP A 185
 None
 0.58A 1nruB-5oydA:
undetectable		 1nruB-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 ILE A 237
TRP A 234
PHE A 250
GLU A 235
 None
 1.33A 1nsiA-5oydA:
undetectable
1nsiB-5oydA:
undetectable		 1nsiA-5oydA:
13.55
1nsiB-5oydA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 TRP A 234
PHE A 250
GLU A 235
ILE A 237
 None
 1.39A 1nsiA-5oydA:
undetectable
1nsiB-5oydA:
undetectable		 1nsiA-5oydA:
13.55
1nsiB-5oydA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 TRP A 234
PHE A 274
GLU A 235
ILE A 237
 None
 1.28A 1nsiA-5oydA:
undetectable
1nsiB-5oydA:
undetectable		 1nsiA-5oydA:
13.55
1nsiB-5oydA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 ILE A 237
TRP A 234
PHE A 250
GLU A 235
 None
 1.28A 1nsiC-5oydA:
0.2
1nsiD-5oydA:
undetectable		 1nsiC-5oydA:
13.55
1nsiD-5oydA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 ILE A 237
TRP A 234
PHE A 274
GLU A 235
 None
 1.30A 1nsiC-5oydA:
0.2
1nsiD-5oydA:
undetectable		 1nsiC-5oydA:
13.55
1nsiD-5oydA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 TRP A 234
PHE A 250
GLU A 235
ILE A 237
 None
 1.32A 1nsiC-5oydA:
0.2
1nsiD-5oydA:
undetectable		 1nsiC-5oydA:
13.55
1nsiD-5oydA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 TRP A 234
PHE A 274
GLU A 235
ILE A 237
 None
 1.28A 1nsiC-5oydA:
0.2
1nsiD-5oydA:
undetectable		 1nsiC-5oydA:
13.55
1nsiD-5oydA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		5 / 12 ILE A 130
HIS A 323
VAL A 164
ALA A 163
LEU A 153
 None
NBG  A 501 ( 3.7A)
None
None
None
 1.09A 1vptA-5oydA:
undetectable		 1vptA-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		5 / 12 ILE A 166
HIS A 323
VAL A 164
ALA A 163
LEU A 153
 None
NBG  A 501 ( 3.7A)
None
None
None
 0.93A 1vptA-5oydA:
undetectable		 1vptA-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 7 ASN A 206
ASN A 129
HIS A 323
VAL A 387
 None
None
NBG  A 501 ( 3.7A)
None
 1.15A 1wu8A-5oydA:
undetectable
1wu8C-5oydA:
undetectable		 1wu8A-5oydA:
14.34
1wu8C-5oydA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		5 / 12 ASP A 433
GLY A 443
GLY A 436
ASN A 437
THR A 133
 None
None
XYS  A 505 ( 3.2A)
None
None
 1.16A 2c49A-5oydA:
undetectable		 2c49A-5oydA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 7 ILE A 237
TRP A 234
PHE A 250
GLU A 235
 None
 1.31A 2nsiC-5oydA:
undetectable
2nsiD-5oydA:
undetectable		 2nsiC-5oydA:
13.55
2nsiD-5oydA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 PHE A 440
ARG A 395
ASN A 434
LEU A 388
 None
None
XYS  A 505 ( 4.1A)
None
 1.13A 2nyrA-5oydA:
undetectable		 2nyrA-5oydA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 8 ARG A 165
SER A 159
VAL A 148
VAL A 164
 None
 0.94A 2y05A-5oydA:
undetectable
2y05B-5oydA:
undetectable		 2y05A-5oydA:
15.38
2y05B-5oydA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_B_TESB340_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		5 / 10 ILE A 207
TRP A 234
ASN A 129
VAL A 164
VAL A 203
 None
 1.04A 3burB-5oydA:
9.8		 3burB-5oydA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 8 TRP A 234
PHE A 250
GLU A 235
ILE A 237
 None
 1.34A 3e7gC-5oydA:
undetectable
3e7gD-5oydA:
undetectable		 3e7gC-5oydA:
11.79
3e7gD-5oydA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		5 / 11 ARG A 447
ALA A 163
GLY A 389
PRO A 167
ILE A 130
 None
 1.13A 3ebzA-5oydA:
undetectable		 3ebzA-5oydA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ASN A 439
ASP A 454
GLN A 456
 None
 0.71A 3eeyC-5oydA:
undetectable		 3eeyC-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ASN A 439
ASP A 454
GLN A 456
 None
 0.73A 3eeyD-5oydA:
undetectable		 3eeyD-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ASN A 439
ASP A 454
GLN A 456
 None
 0.71A 3eeyE-5oydA:
undetectable		 3eeyE-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ARG A 425
ASP A 381
ASP A 373
 None
 0.62A 3jayA-5oydA:
undetectable		 3jayA-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ARG A 425
ASP A 381
ASP A 373
 None
 0.66A 3jb2A-5oydA:
undetectable		 3jb2A-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		3 / 3 ARG A 425
ASP A 381
ASP A 373
 None
 0.79A 3jb3A-5oydA:
undetectable		 3jb3A-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		5 / 12 GLU A 135
ASP A 433
GLY A 443
ARG A 395
ASN A 439
 None
 1.41A 3jzjA-5oydA:
undetectable		 3jzjA-5oydA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 ILE A 197
LEU A 248
MET A 113
THR A 111
 None
 1.18A 3wg7A-5oydA:
undetectable
3wg7J-5oydA:
undetectable		 3wg7A-5oydA:
undetectable
3wg7J-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 7 TRP A 234
PHE A 250
GLU A 235
ILE A 237
 None
 1.28A 4cx7C-5oydA:
undetectable
4cx7D-5oydA:
undetectable		 4cx7C-5oydA:
13.55
4cx7D-5oydA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 GLY A 211
ASN A 257
GLU A 215
GLN A 176
 None
 1.26A 4g0vB-5oydA:
undetectable		 4g0vB-5oydA:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 5 GLU A 321
VAL A 387
LEU A 204
PHE A 430
 None
 0.72A 4lb0B-5oydA:
undetectable		 4lb0B-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 7 TRP A 234
PHE A 250
GLU A 235
ILE A 237
 None
 1.31A 4nosA-5oydA:
undetectable
4nosB-5oydA:
undetectable		 4nosA-5oydA:
13.58
4nosB-5oydA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 7 ILE A 237
TRP A 234
PHE A 250
GLU A 235
 None
 1.33A 4nosC-5oydA:
undetectable
4nosD-5oydA:
undetectable		 4nosC-5oydA:
13.58
4nosD-5oydA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 TRP A 234
PHE A 250
GLU A 235
ILE A 237
 None
 1.30A 4nosC-5oydA:
undetectable
4nosD-5oydA:
undetectable		 4nosC-5oydA:
13.58
4nosD-5oydA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		5 / 9 VAL A 193
VAL A 189
ILE A 237
PHE A 250
LEU A 248
 None
 1.42A 5e4dA-5oydA:
undetectable		 5e4dA-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		5 / 11 ALA A 320
VAL A 322
GLU A 321
ASP A 298
ILE A 299
 None
 1.18A 5i3cC-5oydA:
undetectable		 5i3cC-5oydA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5oyd CELLULASE, PUTATIVE,
CEL5D
(Cellvibrio
japonicus) 		4 / 6 VAL A 192
VAL A 164
ILE A 444
PHE A 445
 None
 1.05A 5jw1B-5oydA:
undetectable		 5jw1B-5oydA:
8.33