SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oyp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 5oyp STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 5 TYR B  83
PRO B  85
LEU B 112
ARG B 152
 None
 1.22A 1i2wA-5oypB:
undetectable		 1i2wA-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 5oyp STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 6 PRO B 220
PHE B 221
GLU B 113
VAL B 166
 None
 1.45A 1l2iB-5oypB:
undetectable		 1l2iB-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 5oyp STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 8 SER B  16
THR B  25
ASP B  27
GLU B   6
 None
 1.20A 1mxgA-5oypB:
undetectable		 1mxgA-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5oyp STRUCTURAL PROTEIN
VP2
STRUCTURAL PROTEIN
VP3
(Sacbrood
virus;
Sacbrood
virus) 		4 / 8 THR C  66
ARG C  89
LEU B 203
ASP B  77
 None
 1.07A 2zw9A-5oypC:
undetectable		 2zw9A-5oypC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 5oyp STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		3 / 3 ARG C 217
HIS C 151
SER C 135
 None
 0.96A 4mjwA-5oypC:
undetectable
4mjwB-5oypC:
undetectable		 4mjwA-5oypC:
undetectable
4mjwB-5oypC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 5oyp STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		3 / 3 SER C 135
ARG C 217
HIS C 151
 None
 0.92A 4mjwA-5oypC:
undetectable
4mjwB-5oypC:
undetectable		 4mjwA-5oypC:
undetectable
4mjwB-5oypC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 5oyp STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		3 / 3 SER B 136
ASP B 140
GLN B  81
 None
 0.96A 4oltA-5oypB:
undetectable
4oltB-5oypB:
undetectable		 4oltA-5oypB:
undetectable
4oltB-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 5oyp STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		3 / 3 GLU B  20
LYS B  18
ASN B  59
 None
 1.04A 4y1dA-5oypB:
undetectable
4y1dD-5oypB:
undetectable		 4y1dA-5oypB:
undetectable
4y1dD-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5oyp STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		4 / 7 TYR C 172
ILE C 116
GLY C  87
THR C 182
 None
 0.91A 4ze3A-5oypC:
undetectable		 4ze3A-5oypC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 5oyp STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 6 TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.07A 5bmvB-5oypB:
undetectable		 5bmvB-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 5oyp STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		5 / 11 ASN B  21
TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.13A 5jh7D-5oypB:
undetectable		 5jh7D-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 5oyp STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		4 / 6 GLY C  87
PRO C  86
THR C 182
SER C 210
 None
 1.06A 5ny7A-5oypC:
undetectable		 5ny7A-5oypC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5oyp STRUCTURAL PROTEIN
VP2
STRUCTURAL PROTEIN
VP3
(Sacbrood
virus;
Sacbrood
virus) 		3 / 3 MET B 156
ASP C 121
ARG C 239
 None
 1.16A 5z6jA-5oypB:
undetectable		 5z6jA-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5oyp STRUCTURAL PROTEIN
VP2
STRUCTURAL PROTEIN
VP3
(Sacbrood
virus;
Sacbrood
virus) 		3 / 3 MET B 156
ASP C 121
ARG C 239
 None
 1.06A 5z6kA-5oypB:
undetectable		 5z6kA-5oypB:
undetectable