SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5pep'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.02A 1c8lA-5pepA:
undetectable		 1c8lA-5pepA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.04A 1gfzA-5pepA:
undetectable		 1gfzA-5pepA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.06A 1l5qA-5pepA:
undetectable		 1l5qA-5pepA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.05A 1l5qB-5pepA:
undetectable		 1l5qB-5pepA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.03A 1l7xA-5pepA:
undetectable		 1l7xA-5pepA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.05A 1l7xB-5pepA:
undetectable		 1l7xB-5pepA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 5pep PEPSIN
(Sus
scrofa) 		4 / 7 GLY A 119
MET A  80
ILE A  30
VAL A  29
 None
 1.06A 1rxcC-5pepA:
undetectable		 1rxcC-5pepA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 5pep PEPSIN
(Sus
scrofa) 		4 / 7 GLY A 119
MET A  80
ILE A  30
VAL A  29
 None
 1.03A 1rxcD-5pepA:
undetectable		 1rxcD-5pepA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 5pep PEPSIN
(Sus
scrofa) 		3 / 3 PRO A 116
ASP A 118
ASP A  52
 None
 0.81A 1sqfA-5pepA:
undetectable		 1sqfA-5pepA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 5pep PEPSIN
(Sus
scrofa) 		5 / 11 LEU A 155
ASP A 304
GLY A  34
VAL A 153
ILE A 307
 None
 0.92A 1t3rB-5pepA:
6.9		 1t3rB-5pepA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 5pep PEPSIN
(Sus
scrofa) 		5 / 9 LEU A 155
ASP A 304
ILE A 213
GLY A  34
VAL A 153
 None
 1.09A 2avoA-5pepA:
6.7		 2avoA-5pepA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 5pep PEPSIN
(Sus
scrofa) 		4 / 8 VAL A 165
VAL A 153
LEU A 123
THR A  33
 None
 0.91A 2gehA-5pepA:
undetectable		 2gehA-5pepA:
21.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 5pep PEPSIN
(Sus
scrofa) 		8 / 12 ASP A  32
GLY A  34
SER A  35
TYR A  75
PHE A 117
ASP A 215
GLY A 217
SER A 219
 None
 0.57A 2v0zC-5pepA:
44.5		 2v0zC-5pepA:
39.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 ASP A 215
GLY A 217
ASP A  32
GLY A  34
SER A  36
 None
 0.91A 2v0zC-5pepA:
44.5		 2v0zC-5pepA:
39.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 5pep PEPSIN
(Sus
scrofa) 		7 / 12 ASP A  32
GLY A  34
ALA A 115
PHE A 117
ASP A 215
GLY A 217
SER A 219
 None
 0.64A 2v0zO-5pepA:
44.9		 2v0zO-5pepA:
39.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_2
(RENIN)		 5pep PEPSIN
(Sus
scrofa) 		4 / 8 TYR A  14
SER A  35
TYR A  75
THR A  77
 None
 0.63A 2v0zO-5pepA:
44.9		 2v0zO-5pepA:
39.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 5 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.05A 3bcrA-5pepA:
undetectable		 3bcrA-5pepA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 VAL A 165
VAL A 153
LEU A 123
THR A  33
VAL A 136
 None
 1.18A 3czvA-5pepA:
undetectable
3czvB-5pepA:
undetectable		 3czvA-5pepA:
21.99
3czvB-5pepA:
21.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 5pep PEPSIN
(Sus
scrofa) 		6 / 12 ASP A  32
GLY A  34
THR A  77
PHE A 117
ASP A 215
SER A 219
 None
 0.81A 3d91A-5pepA:
44.6		 3d91A-5pepA:
39.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_B_REMB350_1
(RENIN)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  34
THR A  77
ASP A 215
SER A 219
 None
 0.50A 3d91B-5pepA:
44.5		 3d91B-5pepA:
39.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.06A 3dd1A-5pepA:
undetectable		 3dd1A-5pepA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.04A 3dd1B-5pepA:
undetectable		 3dd1B-5pepA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.07A 3ddsA-5pepA:
undetectable		 3ddsA-5pepA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.07A 3ddsB-5pepA:
undetectable		 3ddsB-5pepA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.07A 3ddwA-5pepA:
undetectable		 3ddwA-5pepA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.04A 3ddwB-5pepA:
undetectable		 3ddwB-5pepA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 4 ARG A 316
ASP A 142
ASP A 138
PRO A 126
 None
 1.26A 3fgrB-5pepA:
undetectable		 3fgrB-5pepA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 5pep PEPSIN
(Sus
scrofa) 		4 / 4 ARG A 316
ASP A 142
ASP A 138
PRO A 135
 None
 1.36A 3fgrB-5pepA:
undetectable		 3fgrB-5pepA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAM_A_LLLA500_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 SER A 129
ASN A  37
ASP A 138
ASP A 142
TYR A  86
 None
 1.19A 3hamA-5pepA:
undetectable		 3hamA-5pepA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 GLY A 119
MET A  80
ILE A  30
VAL A  29
 None
 1.05A 3kvvB-5pepA:
undetectable		 3kvvB-5pepA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 GLY A 119
MET A  80
ILE A  30
VAL A  29
 None
 1.04A 3kvvC-5pepA:
undetectable		 3kvvC-5pepA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 GLY A 119
MET A  80
ILE A  30
VAL A  29
 None
 1.08A 3kvvD-5pepA:
undetectable		 3kvvD-5pepA:
19.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 5pep PEPSIN
(Sus
scrofa) 		6 / 12 ASP A  32
GLY A  34
GLY A  76
ASP A 215
THR A 218
ILE A 301
 None
 0.53A 3prsA-5pepA:
38.5		 3prsA-5pepA:
31.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  76
ILE A 213
THR A 218
ILE A 301
 None
 0.49A 3pwwA-5pepA:
38.4		 3pwwA-5pepA:
31.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 5pep PEPSIN
(Sus
scrofa) 		5 / 8 GLY A  34
SER A  35
ILE A  73
TYR A  75
ASP A 215
 None
 0.46A 3pwwA-5pepA:
38.4		 3pwwA-5pepA:
31.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 5pep PEPSIN
(Sus
scrofa) 		7 / 12 ILE A  30
ASP A  32
GLY A  34
GLY A  76
ASP A 215
THR A 218
ILE A 301
 None
 0.45A 3q70A-5pepA:
12.8		 3q70A-5pepA:
33.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
ASP A  32
ILE A 120
 None
 0.57A 3q70A-5pepA:
12.8		 3q70A-5pepA:
33.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
GLY A  76
ASP A  32
 None
 0.57A 3q70A-5pepA:
12.8		 3q70A-5pepA:
33.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 SER A  35
ILE A  73
TYR A  75
ASP A 118
 None
 0.98A 3q70A-5pepA:
12.8		 3q70A-5pepA:
33.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		7 / 12 ILE A  30
ASP A  32
GLY A  34
ILE A  73
GLY A  76
ASP A 215
ILE A 301
 None
 0.65A 3tneA-5pepA:
37.0		 3tneA-5pepA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
ASP A  32
ILE A 120
 None
 0.61A 3tneA-5pepA:
37.0		 3tneA-5pepA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
GLY A  76
ASP A  32
 None
 0.77A 3tneA-5pepA:
37.0		 3tneA-5pepA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		7 / 12 ILE A  30
ASP A  32
GLY A  34
ILE A  73
GLY A  76
ASP A 215
ILE A 301
 None
 0.66A 3tneB-5pepA:
37.0		 3tneB-5pepA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		6 / 12 ILE A 120
ASP A  32
GLY A  34
GLY A  76
ASP A 215
ILE A 301
 None
 1.46A 3tneB-5pepA:
37.0		 3tneB-5pepA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
ASP A  32
ILE A 120
 None
 0.59A 3tneB-5pepA:
37.0		 3tneB-5pepA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
GLY A  76
ASP A  32
 None
 0.72A 3tneB-5pepA:
37.0		 3tneB-5pepA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		4 / 7 SER A  35
TYR A  75
ILE A 120
THR A 218
 None
 0.67A 3tneB-5pepA:
37.0		 3tneB-5pepA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		5 / 10 ASP A 215
GLY A 217
GLY A  76
LEU A 299
ILE A 301
 None
 0.93A 3ttpA-5pepA:
6.7		 3ttpA-5pepA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		5 / 10 ASP A 215
GLY A 217
GLY A  76
LEU A 299
ILE A 301
 None
 0.93A 3ttpB-5pepA:
6.7		 3ttpB-5pepA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		5 / 11 LEU A 155
ASP A 304
GLY A  34
VAL A 153
ILE A 307
 None
 0.95A 4dqeA-5pepA:
6.5		 4dqeA-5pepA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 5pep PEPSIN
(Sus
scrofa) 		5 / 11 LEU A 155
ASP A 304
GLY A  34
VAL A 153
ILE A 307
 None
 0.95A 4dqhA-5pepA:
6.4		 4dqhA-5pepA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 5pep PEPSIN
(Sus
scrofa) 		3 / 3 ASP A 149
ARG A 316
ASP A 142
 None
 0.77A 4fp9D-5pepA:
undetectable		 4fp9D-5pepA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5pep PEPSIN
(Sus
scrofa) 		3 / 3 ASP A 149
ARG A 316
ASP A 142
 None
 0.81A 4fzvA-5pepA:
undetectable		 4fzvA-5pepA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 5pep PEPSIN
(Sus
scrofa) 		3 / 3 ASP A 215
ASP A  32
ASN A  37
 None
 0.51A 4q5mA-5pepA:
9.7		 4q5mA-5pepA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 5pep PEPSIN
(Sus
scrofa) 		5 / 9 ALA A 115
PHE A 117
ILE A  73
GLY A  78
SER A 219
 None
 1.25A 4r20B-5pepA:
undetectable		 4r20B-5pepA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5pep PEPSIN
(Sus
scrofa) 		4 / 7 TYR A 310
ALA A 274
ILE A 259
LEU A 221
 None
 0.67A 4uymB-5pepA:
undetectable		 4uymB-5pepA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5pep PEPSIN
(Sus
scrofa) 		4 / 8 ASN A  57
PRO A  58
PHE A  64
SER A  62
 None
 1.37A 5amiB-5pepA:
undetectable		 5amiB-5pepA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 5pep PEPSIN
(Sus
scrofa) 		5 / 11 PHE A 306
ILE A 307
LEU A   6
ASP A  32
GLY A 217
 None
 1.36A 5fctA-5pepA:
undetectable		 5fctA-5pepA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 5pep PEPSIN
(Sus
scrofa) 		4 / 5 SER A 251
SER A 252
SER A 249
SER A 255
 None
 1.48A 5hswA-5pepA:
undetectable		 5hswA-5pepA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5pep PEPSIN
(Sus
scrofa) 		4 / 6 PHE A 314
VAL A 153
ILE A 307
ASP A 304
 None
 1.29A 5iwuA-5pepA:
undetectable		 5iwuA-5pepA:
21.43