SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5pq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5pq9 BROMODOMAIN-CONTAINI
NG PROTEIN 1
(Homo
sapiens) 		3 / 3 ASP A  50
ARG A  53
ASP A  76
 None
 0.88A 4fzvA-5pq9A:
undetectable		 4fzvA-5pq9A:
16.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5pq9 BROMODOMAIN-CONTAINI
NG PROTEIN 1
(Homo
sapiens) 		4 / 6 VAL A  59
VAL A  64
TYR A  67
ASN A 110
 EDO  A 202 (-4.5A)
None
None
EDO  A 201 (-3.2A)
 0.41A 5pbeA-5pq9A:
15.3		 5pbeA-5pq9A:
42.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5pq9 BROMODOMAIN-CONTAINI
NG PROTEIN 1
(Homo
sapiens) 		4 / 8 VAL A  59
CYH A 106
TYR A 109
ASN A 110
 EDO  A 202 (-4.5A)
EDO  A 202 (-3.4A)
EDO  A 201 (-4.7A)
EDO  A 201 (-3.2A)
 0.39A 5y1yA-5pq9A:
13.6		 5y1yA-5pq9A:
28.75