SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5pwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 5pwy NUCLEAR AUTOANTIGEN
SP-100
(Homo
sapiens) 		4 / 7 LEU A 782
ILE A 743
ARG A 746
TYR A 787
 None
 1.22A 2hc4A-5pwyA:
undetectable		 2hc4A-5pwyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 5pwy NUCLEAR AUTOANTIGEN
SP-100
(Homo
sapiens) 		4 / 6 LEU A 815
SER A 797
ILE A 840
PHE A 847
 None
 0.92A 3ko0B-5pwyA:
undetectable		 3ko0B-5pwyA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 5pwy NUCLEAR AUTOANTIGEN
SP-100
(Homo
sapiens) 		4 / 6 LEU A 815
SER A 797
ILE A 840
PHE A 847
 None
 0.83A 3ko0S-5pwyA:
undetectable		 3ko0S-5pwyA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5pwy NUCLEAR AUTOANTIGEN
SP-100
(Homo
sapiens) 		4 / 8 LEU A 822
TYR A 827
PHE A 833
TYR A 787
 None
 1.36A 3po7A-5pwyA:
undetectable		 3po7A-5pwyA:
14.56