SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5suh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		4 / 7 PHE A  26
TYR A  29
ALA A 166
ALA A 162
 None
 0.82A 2wx2A-5suhA:
undetectable		 2wx2A-5suhA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  75
ILE A  58
VAL A  85
ILE A  49
ALA A  99
 None
 0.84A 3ekwB-5suhA:
undetectable		 3ekwB-5suhA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  77
LEU A  48
LEU A  17
GLY A  84
GLU A  51
 None
 0.99A 3g2oB-5suhA:
undetectable		 3g2oB-5suhA:
28.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  75
GLY A  38
PRO A  41
ALA A  47
LEU A  77
 None
 0.82A 3mteA-5suhA:
undetectable		 3mteA-5suhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  75
GLY A  38
PRO A  41
ALA A  47
LEU A  77
 None
 0.90A 3p2kA-5suhA:
undetectable		 3p2kA-5suhA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  75
GLY A  38
PRO A  41
ALA A  47
LEU A  77
 None
 0.86A 3p2kB-5suhA:
undetectable		 3p2kB-5suhA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  75
GLY A  38
PRO A  41
ALA A  47
LEU A  77
 None
 0.89A 3p2kC-5suhA:
undetectable		 3p2kC-5suhA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  75
GLY A  38
PRO A  41
ALA A  47
LEU A  77
 None
 0.88A 3p2kD-5suhA:
undetectable		 3p2kD-5suhA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A  15
ILE A 192
ILE A 206
VAL A 209
LEU A 210
 None
 0.98A 3w67B-5suhA:
undetectable		 3w67B-5suhA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		4 / 4 ALA A 162
ALA A 165
ALA A 166
ALA A 169
 None
 0.13A 4oadA-5suhA:
undetectable		 4oadA-5suhA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5suh MSM0271 PROTEIN
(Mycolicibacteriu
m
smegmatis) 		4 / 4 ALA A 162
ALA A 165
ALA A 166
ALA A 169
 None
 0.12A 4oaeA-5suhA:
undetectable		 4oaeA-5suhA:
23.58