SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5sui'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 301
ILE A 372
TYR A 343
VAL A 338
 None
 1.01A 1db1A-5suiA:
undetectable		 1db1A-5suiA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 162
PHE A 228
LEU A 183
ALA A 184
ILE A 172
 None
 1.22A 1g5yC-5suiA:
undetectable		 1g5yC-5suiA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 347
THR A 341
GLN A 310
ILE A 409
 None
 1.15A 1ss4A-5suiA:
undetectable		 1ss4A-5suiA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 7 ALA A  66
ARG A  54
TYR A  51
PHE A 123
 None
 1.08A 2ajvH-5suiA:
undetectable
2ajvL-5suiA:
undetectable		 2ajvH-5suiA:
19.43
2ajvL-5suiA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		5 / 9 THR A 289
LEU A 271
ALA A 211
TYR A 212
LEU A 231
 None
 1.33A 2azqA-5suiA:
undetectable		 2azqA-5suiA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 271
ASN A 272
GLU A 201
LEU A 200
 None
 1.20A 2w8yA-5suiA:
undetectable		 2w8yA-5suiA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		6 / 12 GLY A 361
LEU A 380
VAL A 347
THR A 341
ASP A 364
ILE A 365
 None
 1.23A 2wa2B-5suiA:
undetectable		 2wa2B-5suiA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 8 THR A 341
GLN A 382
ARG A 390
SER A 309
 None
 1.10A 2xytH-5suiA:
undetectable		 2xytH-5suiA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 313
VAL A 338
GLN A 310
PHE A 258
 None
 1.35A 3bjwB-5suiA:
undetectable		 3bjwB-5suiA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		5 / 12 GLU A 312
ASP A 376
ASN A 320
GLY A 326
ARG A  54
 None
 1.38A 4djeB-5suiA:
undetectable		 4djeB-5suiA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 286
LEU A 284
ALA A 276
 None
 0.84A 4iizA-5suiA:
undetectable		 4iizA-5suiA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 209
PHE A 275
LEU A 221
LEU A 256
PHE A 194
 None
 1.48A 4qopA-5suiA:
undetectable		 4qopA-5suiA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 209
PHE A 275
LEU A 221
LEU A 256
PHE A 194
 None
 1.47A 4qopB-5suiA:
undetectable		 4qopB-5suiA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		5 / 8 ILE A 209
PHE A 275
LEU A 221
LEU A 256
PHE A 194
 None
 1.48A 4qopC-5suiA:
undetectable		 4qopC-5suiA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  58
ALA A 162
ILE A  64
CYH A 149
PRO A 150
 None
 1.46A 5mlmA-5suiA:
undetectable		 5mlmA-5suiA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 6 MET A 414
ASN A 410
VAL A  10
LEU A   8
 None
 1.41A 5xdhA-5suiA:
undetectable
5xdhC-5suiA:
undetectable		 5xdhA-5suiA:
10.25
5xdhC-5suiA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 5 MET A 414
ASN A 410
VAL A  10
LEU A   8
 None
 1.33A 5xdhB-5suiA:
undetectable		 5xdhB-5suiA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 5 MET A 414
ASN A 410
VAL A  10
LEU A   8
 None
 1.18A 5xdhD-5suiA:
undetectable		 5xdhD-5suiA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 143
GLY A 187
SER A 166
GLY A 167
 None
 0.70A 6ekzA-5suiA:
undetectable		 6ekzA-5suiA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5sui RIBOSOME BIOGENESIS
PROTEIN NSA1
(Saccharomyces
cerevisiae) 		4 / 5 VAL A  13
PHE A 194
MET A 254
GLY A 214
 None
 1.18A 6hd4A-5suiA:
undetectable		 6hd4A-5suiA:
12.60