SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5suj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
4 / 7 ILE A 134
ARG A 338
ILE A 138
PHE A 246
None
0.99A 2q6hA-5sujA:
undetectable
2q6hA-5sujA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
5 / 12 ILE A 229
LEU A 194
GLU A 169
THR A 150
ILE A 198
None
1.18A 2vn0A-5sujA:
undetectable
2vn0A-5sujA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
5 / 12 ILE A 229
PHE A 195
LEU A 194
GLU A 169
THR A 150
None
1.20A 2vn0A-5sujA:
undetectable
2vn0A-5sujA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
4 / 5 TYR A 293
ILE A 248
LEU A 122
LEU A 118
None
1.01A 2zb7A-5sujA:
undetectable
2zb7A-5sujA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
4 / 7 TYR A 173
GLU A 158
LEU A 168
ASN A 152
None
1.41A 3k8mA-5sujA:
undetectable
3k8mA-5sujA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
5 / 12 LEU A 167
LEU A 147
LEU A 206
LYS A 190
GLN A 193
None
1.28A 4f4dA-5sujA:
undetectable
4f4dA-5sujA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFX_A_ACTA404_0
(THIAMINE
BIOSYNTHESIS
LIPOPROTEIN APBE)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
4 / 5 SER A 243
ARG A 140
LEU A 337
ASP A 139
None
1.36A 4ifxA-5sujA:
undetectable
4ifxA-5sujA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
4 / 7 GLY A  84
GLN A  85
TYR A 267
SER A 245
None
1.01A 4ws0A-5sujA:
undetectable
4ws0A-5sujA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
4 / 8 GLY A  84
GLN A  85
TYR A 267
SER A 245
None
1.02A 4ws1A-5sujA:
undetectable
4ws1A-5sujA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
3 / 3 VAL A  38
ALA A  40
PHE A 361
None
0.70A 4z4iA-5sujA:
undetectable
4z4iA-5sujA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
3 / 3 VAL A  38
ALA A  40
PHE A 361
None
0.72A 5js1A-5sujA:
undetectable
5js1A-5sujA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
3 / 3 CYH A  73
LYS A  71
HIS A  74
None
1.11A 5js5A-5sujA:
undetectable
5js5A-5sujA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila)
3 / 3 HIS A  21
LYS A  22
PHE A  18
None
1.07A 5klaA-5sujA:
undetectable
5klaA-5sujA:
21.58