SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5suo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.16A 1kifA-5suoA:
undetectable		 1kifA-5suoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.16A 1kifB-5suoA:
undetectable		 1kifB-5suoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.16A 1kifC-5suoA:
undetectable		 1kifC-5suoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.16A 1kifD-5suoA:
undetectable		 1kifD-5suoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.16A 1kifE-5suoA:
undetectable		 1kifE-5suoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.16A 1kifF-5suoA:
undetectable		 1kifF-5suoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.16A 1kifG-5suoA:
undetectable		 1kifG-5suoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.16A 1kifH-5suoA:
undetectable		 1kifH-5suoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 ASP A 175
PHE A 164
VAL A 179
 None
 0.65A 1kijB-5suoA:
undetectable		 1kijB-5suoA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.12A 1ve9A-5suoA:
undetectable		 1ve9A-5suoA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.20A 2du8G-5suoA:
undetectable		 2du8G-5suoA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 TYR A 115
TYR A 106
ILE A 107
GLY A 113
 None
 1.10A 2du8J-5suoA:
undetectable		 2du8J-5suoA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 ASN A 161
ILE A 305
LEU A 295
GLY A 286
ASN A 155
 None
 1.25A 2e7fA-5suoA:
undetectable		 2e7fA-5suoA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEK_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 GLY A 140
ASN A 141
TYR A 106
ASN A 315
PHE A 423
 None
 1.48A 3mekA-5suoA:
undetectable		 3mekA-5suoA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 ASN A 141
ALA A 149
PRO A 151
ALA A 321
 None
 1.10A 3twpA-5suoA:
undetectable		 3twpA-5suoA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 ASN A 141
ALA A 149
PRO A 151
ALA A 321
 None
 1.10A 3twpB-5suoA:
undetectable		 3twpB-5suoA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 ASN A 141
ALA A 149
PRO A 151
ALA A 321
 None
 1.11A 3twpC-5suoA:
undetectable		 3twpC-5suoA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 ASN A 141
ALA A 149
PRO A 151
ALA A 321
 None
 1.12A 3twpD-5suoA:
undetectable		 3twpD-5suoA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU A 169
VAL A 199
ILE A 308
VAL A 188
LEU A 189
 IOD  A 515 ( 4.6A)
None
None
None
None
 1.06A 3w67B-5suoA:
undetectable		 3w67B-5suoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 TYR A 377
VAL A 353
TYR A 354
LEU A 294
 None
None
None
IOD  A 505 ( 4.9A)
 1.01A 4jtrA-5suoA:
undetectable		 4jtrA-5suoA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 LEU A 228
ASP A 215
VAL A 235
THR A 232
ILE A 226
 IOD  A 506 ( 4.3A)
IOD  A 516 ( 4.8A)
None
None
None
 0.94A 4njuB-5suoA:
undetectable		 4njuB-5suoA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 LEU A 228
ASP A 215
VAL A 235
THR A 232
ILE A 226
 IOD  A 506 ( 4.3A)
IOD  A 516 ( 4.8A)
None
None
None
 0.95A 4njuD-5suoA:
undetectable		 4njuD-5suoA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 TYR A  46
TYR A  78
SER A 326
ALA A 149
ALA A 103
 None
 1.44A 4ymgA-5suoA:
undetectable		 4ymgA-5suoA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 LYS A 409
LEU A 412
ASN A 155
PRO A 287
 None
None
None
IOD  A 501 ( 4.3A)
 1.39A 4yv5B-5suoA:
undetectable		 4yv5B-5suoA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 LYS A 409
LEU A 412
ASN A 155
PRO A 287
 None
None
None
IOD  A 501 ( 4.3A)
 1.38A 4yv5A-5suoA:
undetectable		 4yv5A-5suoA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 LEU A 251
PRO A 210
GLU A 183
TYR A 182
 None
 1.27A 4z4gA-5suoA:
undetectable		 4z4gA-5suoA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		5 / 11 TYR A 216
PHE A 214
VAL A 241
ILE A 448
ILE A 308
 IOD  A 516 (-4.9A)
None
None
None
None
 1.12A 5hw8A-5suoA:
undetectable
5hw8D-5suoA:
undetectable		 5hw8A-5suoA:
14.82
5hw8D-5suoA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJO_A_SAMA505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 GLY A 140
ASN A 141
TYR A 106
ASN A 315
PHE A 423
 None
 1.48A 5yjoA-5suoA:
undetectable		 5yjoA-5suoA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		5 / 9 VAL A 353
HIS A 382
GLY A 385
ILE A 338
LEU A 341
 None
 1.46A 6c2mC-5suoA:
undetectable		 6c2mC-5suoA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN
(Streptococcus
pneumoniae) 		4 / 5 ASN A 380
TYR A 354
GLY A 351
HIS A 382
 None
 1.18A 6gh9A-5suoA:
undetectable		 6gh9A-5suoA:
8.37