SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5sv6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		4 / 4 ARG A  70
ALA A  65
ALA A 261
GLU A 257
 None
 1.19A 1e7bA-5sv6A:
undetectable		 1e7bA-5sv6A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		4 / 5 PHE A 175
ILE A 146
PRO A 148
GLU A 153
 None
 1.36A 1oniG-5sv6A:
undetectable
1oniH-5sv6A:
undetectable		 1oniG-5sv6A:
19.31
1oniH-5sv6A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		5 / 12 THR A 109
GLY A  99
GLN A 252
ASP A 251
ASP A 104
 None
 1.18A 1wg8B-5sv6A:
undetectable		 1wg8B-5sv6A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		3 / 3 PRO A 123
PHE A 120
LYS A 221
 None
 1.28A 3bjwG-5sv6A:
undetectable		 3bjwG-5sv6A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		4 / 4 ARG A 106
ASP A 101
ASP A 104
PRO A 105
 None
 1.17A 3fgrB-5sv6A:
undetectable		 3fgrB-5sv6A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		5 / 12 ILE A 245
GLU A  57
GLN A  59
LEU A  72
VAL A  96
 None
 1.15A 3ix9A-5sv6A:
undetectable		 3ix9A-5sv6A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		5 / 12 GLY A  99
VAL A  97
SER A  49
PRO A  47
GLU A  45
 None
 1.47A 4bvaA-5sv6A:
undetectable		 4bvaA-5sv6A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		5 / 12 GLY A  99
VAL A  97
SER A  49
PRO A  47
GLU A  45
 None
 1.45A 4bvaB-5sv6A:
undetectable		 4bvaB-5sv6A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		4 / 7 TYR A 113
GLU A  57
TYR A  48
GLU A 276
 None
 1.25A 4mi4A-5sv6A:
undetectable
4mi4C-5sv6A:
undetectable		 4mi4A-5sv6A:
22.71
4mi4C-5sv6A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_A_PARA500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		5 / 10 SER A 249
THR A 109
GLU A 242
ASP A 111
GLY A 103
 None
 1.46A 4qb9A-5sv6A:
undetectable		 4qb9A-5sv6A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3
(Methylophaga
aminisulfidivora
ns) 		4 / 7 LEU A  60
VAL A  39
GLN A  53
GLU A  54
 None
 1.10A 5tudA-5sv6A:
undetectable		 5tudA-5sv6A:
20.92