SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5sv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		4 / 7 TYR A  77
THR A 271
TYR A 128
ASN A 279
 None
 0.91A 2g70A-5sv9A:
undetectable		 2g70A-5sv9A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		4 / 7 TYR A  77
THR A 271
TYR A 128
ASN A 279
 None
 0.95A 2g70B-5sv9A:
undetectable		 2g70B-5sv9A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		5 / 12 PHE A 330
LEU A 155
GLN A 358
PRO A 162
VAL A 491
 None
 1.37A 2qd4A-5sv9A:
undetectable		 2qd4A-5sv9A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		3 / 3 LYS A 323
ARG A 369
VAL A 375
 None
 1.11A 2r2vC-5sv9A:
undetectable
2r2vD-5sv9A:
undetectable		 2r2vC-5sv9A:
5.13
2r2vD-5sv9A:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		4 / 4 LEU A 412
ASP A 197
VAL A 204
THR A 248
 None
 1.14A 3cyxB-5sv9A:
undetectable		 3cyxB-5sv9A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		4 / 8 GLY A 467
GLY A 470
ILE A 474
SER A 490
 None
 0.64A 3d41A-5sv9A:
undetectable		 3d41A-5sv9A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		4 / 8 LEU A 415
MET A 425
LEU A 361
HIS A 362
 None
 0.96A 4ok1A-5sv9A:
undetectable		 4ok1A-5sv9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		5 / 12 PHE A 330
LEU A 101
SER A 328
ASP A  38
GLY A  94
 None
 1.42A 4qb9E-5sv9A:
undetectable		 4qb9E-5sv9A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		4 / 5 TYR A  55
LEU A 412
PRO A  61
LEU A 404
 None
 1.08A 5eshA-5sv9A:
undetectable		 5eshA-5sv9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		5 / 10 VAL A 312
TYR A 307
ASP A 309
SER A 313
ILE A 356
 None
 1.26A 5u98A-5sv9A:
undetectable		 5u98A-5sv9A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		5 / 10 VAL A 312
TYR A 307
ASP A 309
SER A 313
ILE A 356
 None
 1.27A 5u98D-5sv9A:
undetectable		 5u98D-5sv9A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		5 / 12 GLY A 354
PRO A 357
ALA A 359
HIS A 362
PHE A 306
 None
 1.12A 5x6yA-5sv9A:
undetectable		 5x6yA-5sv9A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		4 / 5 ALA A 351
SER A 344
GLY A 345
TYR A  77
 None
 0.88A 5yodD-5sv9A:
undetectable		 5yodD-5sv9A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		4 / 6 ASP A  38
GLN A 381
ASN A  44
LEU A 366
 None
 0.99A 6ekuA-5sv9A:
undetectable		 6ekuA-5sv9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 5sv9 BOR1P BORON
TRANSPORTER
(Saccharomyces
mikatae) 		4 / 6 LEU A  60
ALA A  64
SER A 413
ASN A 171
 None
 1.00A 6f88A-5sv9A:
undetectable		 6f88A-5sv9A:
10.29