SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5syd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 4 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.44A 1oe1A-5sydA:
undetectable		 1oe1A-5sydA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 5 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.41A 1oe2A-5sydA:
undetectable		 1oe2A-5sydA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 4 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.45A 1oe3A-5sydA:
undetectable		 1oe3A-5sydA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 4 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.49A 2fqdA-5sydA:
undetectable		 2fqdA-5sydA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 4 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.51A 2fqeA-5sydA:
undetectable		 2fqeA-5sydA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 4 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.49A 2fqfA-5sydA:
undetectable		 2fqfA-5sydA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 4 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.52A 2fqgA-5sydA:
undetectable		 2fqgA-5sydA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 7 VAL A   9
VAL A  55
ASP A  53
VAL A 124
 None
 1.02A 2qbnA-5sydA:
undetectable		 2qbnA-5sydA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 4 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.40A 2xxgA-5sydA:
2.0		 2xxgA-5sydA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 5 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.44A 2xxgC-5sydA:
2.1		 2xxgC-5sydA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 4 PHE A  70
LYS A  82
ILE A 113
THR A  44
 None
 1.47A 3ia4B-5sydA:
undetectable		 3ia4B-5sydA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  28
TYR A  32
VAL A 124
MET A   4
 None
 0.82A 3ik3A-5sydA:
undetectable		 3ik3A-5sydA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 4 HIS A   6
CYH A  72
HIS A  77
MET A  81
 CU  A 202 (-3.3A)
CU  A 202 (-2.4A)
CU  A 202 (-3.4A)
CU  A 202 (-2.8A)
 0.49A 4ef3A-5sydA:
undetectable		 4ef3A-5sydA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 7 SER A  78
GLN A  17
MET A  24
ASP A  22
 None
 1.21A 4hxyB-5sydA:
undetectable		 4hxyB-5sydA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  47
THR A  44
SER A  97
PHE A 108
GLY A 102
 None
 0.91A 4rzvA-5sydA:
undetectable		 4rzvA-5sydA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5syd AZURIN, CHIMERIC
CONSTRUCT
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  28
TYR A  32
ILE A 100
MET A   4
 None
 0.99A 6hd6A-5sydA:
undetectable		 6hd6A-5sydA:
22.48