SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5szj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 5szj RAS-RELATED PROTEIN
RAB-10
(Homo
sapiens) 		4 / 6 PHE A 149
ILE A 157
ALA A 162
MET A  86
 None
 1.15A 1hk2A-5szjA:
undetectable		 1hk2A-5szjA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5szj RAS-RELATED PROTEIN
RAB-10
(Homo
sapiens) 		4 / 8 GLY A 121
GLY A  94
PHE A  97
SER A  96
 None
 0.75A 1jhaA-5szjA:
undetectable		 1jhaA-5szjA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5szj RAS-RELATED PROTEIN
RAB-10
(Homo
sapiens) 		5 / 12 THR A  41
GLY A  21
GLY A  19
GLY A  67
ASP A 125
 MG  A 302 ( 3.1A)
GNP  A 301 (-3.0A)
GNP  A 301 (-3.5A)
GNP  A 301 (-3.2A)
GNP  A 301 (-3.2A)
 0.99A 2b25A-5szjA:
2.5		 2b25A-5szjA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 5szj MICAL
C-TERMINAL-LIKE
PROTEIN
RAS-RELATED PROTEIN
RAB-10
(Homo
sapiens) 		4 / 7 PHE A  38
PHE A  71
PHE B 650
ILE B 657
 GNP  A 301 (-4.0A)
None
None
None
 1.02A 2v0mC-5szjA:
undetectable		 2v0mC-5szjA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5szj MICAL
C-TERMINAL-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 TYR B 603
GLU B 613
ASP B 661
 None
 0.88A 3bxoB-5szjB:
undetectable		 3bxoB-5szjB:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5szj RAS-RELATED PROTEIN
RAB-10
(Homo
sapiens) 		5 / 9 VAL A  88
GLY A 121
GLN A  68
ASN A 122
GLY A  21
 None
None
None
GNP  A 301 (-3.2A)
GNP  A 301 (-3.0A)
 1.44A 3kmoA-5szjA:
undetectable		 3kmoA-5szjA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 5szj RAS-RELATED PROTEIN
RAB-10
(Homo
sapiens) 		4 / 6 LEU A  87
ILE A  15
TYR A  79
VAL A 115
 None
 0.92A 4a9kA-5szjA:
undetectable		 4a9kA-5szjA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 5szj RAS-RELATED PROTEIN
RAB-10
(Homo
sapiens) 		4 / 5 THR A  65
GLY A  16
VAL A  88
TYR A  79
 None
 1.19A 4grkA-5szjA:
undetectable		 4grkA-5szjA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5szj MICAL
C-TERMINAL-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 LEU B 653
ILE B 657
ARG B 660
 None
None
PEG  B 701 (-3.4A)
 0.64A 4mk4B-5szjB:
undetectable		 4mk4B-5szjB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 5szj RAS-RELATED PROTEIN
RAB-10
(Homo
sapiens) 		3 / 3 ARG A 105
ASN A 106
ASP A  17
 None
 0.85A 5gwxA-5szjA:
2.8		 5gwxA-5szjA:
21.02