SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5szm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		5 / 9 LEU A  48
ILE A  37
LEU A  23
VAL A  90
GLY A  89
 None
 1.29A 1e7aA-5szmA:
undetectable		 1e7aA-5szmA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		4 / 7 VAL A  16
GLY A  17
ILE A  77
VAL A  90
 None
 0.75A 1p2yA-5szmA:
undetectable		 1p2yA-5szmA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		4 / 8 ILE A  77
LEU A  66
ILE A  92
PHE A  46
 None
 0.67A 2w9sE-5szmA:
undetectable		 2w9sE-5szmA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		5 / 11 LEU A 299
ILE A 290
LYS A 303
SER A 302
PRO A 216
 None
 1.37A 3bjwE-5szmA:
undetectable		 3bjwE-5szmA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		5 / 12 LEU A  23
LEU A  55
ILE A   2
ILE A  79
PHE A  46
 None
 1.24A 4a79A-5szmA:
undetectable		 4a79A-5szmA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		5 / 11 LEU A  23
LEU A  55
ILE A   2
ILE A  79
PHE A  46
 None
 1.22A 4a7aA-5szmA:
undetectable		 4a7aA-5szmA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		4 / 4 LEU A 183
SER A 144
LEU A 198
LEU A 125
 None
None
MAN  A 515 (-3.6A)
None
 1.12A 4n09A-5szmA:
undetectable		 4n09A-5szmA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		4 / 6 ASN A 146
ILE A 199
ILE A 201
VAL A 111
 None
 0.96A 4olmA-5szmA:
undetectable		 4olmA-5szmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		4 / 4 ASN A  78
LEU A  23
PHE A  46
TYR A   4
 None
 1.26A 4u14A-5szmA:
undetectable		 4u14A-5szmA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8
(Mus
musculus) 		5 / 10 ALA A 121
ILE A 113
PRO A 119
LEU A 171
TYR A 123
 None
 1.02A 4xj7A-5szmA:
undetectable
4xj7B-5szmA:
undetectable		 4xj7A-5szmA:
19.67
4xj7B-5szmA:
19.67