SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5szn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		5 / 11 VAL A 130
TYR A 142
ASN A  99
ALA A 186
SER A 196
 None
None
CA  A 615 (-3.4A)
None
None
 1.28A 2iyfA-5sznA:
undetectable		 2iyfA-5sznA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		5 / 12 VAL A 130
TYR A 142
ASN A  99
ALA A 186
SER A 196
 None
None
CA  A 615 (-3.4A)
None
None
 1.29A 2iyfB-5sznA:
undetectable		 2iyfB-5sznA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		5 / 12 LEU A 262
LEU A 263
LEU A 279
MET A 273
MET A 289
 None
 1.31A 2w8yB-5sznA:
undetectable		 2w8yB-5sznA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		3 / 3 ASP A 295
LYS A 248
ASP A 240
 CA  A 607 (-3.6A)
None
CA  A 607 (-2.4A)
 0.83A 4a7tA-5sznA:
undetectable		 4a7tA-5sznA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		4 / 6 ASP A 416
ASP A 419
ASP A 331
GLU A 330
 CA  A 610 (-3.4A)
CA  A 611 ( 2.2A)
None
CA  A 611 ( 2.1A)
 1.34A 4gkhJ-5sznA:
undetectable		 4gkhJ-5sznA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		5 / 11 VAL A 130
TYR A 142
ASN A  99
ALA A 186
SER A 196
 None
None
CA  A 615 (-3.4A)
None
None
 1.29A 4m83A-5sznA:
undetectable		 4m83A-5sznA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		5 / 11 VAL A 130
TYR A 142
ASN A  99
ALA A 186
SER A 196
 None
None
CA  A 615 (-3.4A)
None
None
 1.29A 4m83B-5sznA:
undetectable		 4m83B-5sznA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		5 / 11 TYR A 187
VAL A 183
ALA A 198
SER A 195
SER A 196
 MAN  A 601 (-4.7A)
None
None
MAN  A 601 (-1.4A)
None
 0.97A 4mmaA-5sznA:
undetectable		 4mmaA-5sznA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		5 / 12 TYR A 187
VAL A 183
ALA A 198
SER A 195
SER A 196
 MAN  A 601 (-4.7A)
None
None
MAN  A 601 (-1.4A)
None
 1.02A 4mmdB-5sznA:
undetectable		 4mmdB-5sznA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		5 / 10 ALA A 122
ILE A 114
PRO A 120
LEU A 172
TYR A 124
 None
 1.02A 4xj7A-5sznA:
undetectable
4xj7B-5sznA:
undetectable		 4xj7A-5sznA:
20.79
4xj7B-5sznA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		4 / 6 GLU A 294
GLY A 297
GLY A 296
ASP A 295
 None
None
None
CA  A 607 (-3.6A)
 0.86A 5a06D-5sznA:
undetectable		 5a06D-5sznA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		4 / 6 GLN A 353
VAL A 354
ALA A 396
THR A 395
 None
 1.00A 6cduB-5sznA:
3.3
6cduC-5sznA:
3.4		 6cduB-5sznA:
19.47
6cduC-5sznA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		4 / 7 ILE A 321
VAL A 319
ALA A 396
THR A 395
 None
 0.94A 6cduC-5sznA:
3.3
6cduD-5sznA:
3.3		 6cduC-5sznA:
19.47
6cduD-5sznA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EID_A_EDTA1111_0
(ARCHAEAL-TYPE OPSIN
2)		 5szn PROTOCADHERIN GAMMA
A9
(Mus
musculus) 		4 / 4 GLN A 498
ASN A 499
PHE A 523
TYR A 494
 None
 1.31A 6eidA-5sznA:
undetectable		 6eidA-5sznA:
20.16