SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5szs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 PHE A 402
ILE A 376
VAL A 373
LEU A 369
VAL A 404
 None
 1.03A 1epbA-5szsA:
undetectable		 1epbA-5szsA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 PHE A 402
ILE A 376
VAL A 373
LEU A 369
VAL A 404
 None
 0.98A 1epbB-5szsA:
undetectable		 1epbB-5szsA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		3 / 3 ALA A  51
VAL A 182
TRP A  48
 None
 1.01A 1gmkC-5szsA:
undetectable
1gmkD-5szsA:
undetectable		 1gmkC-5szsA:
1.75
1gmkD-5szsA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 ASP A 393
HIS A 542
THR A 319
PRO A 536
GLY A 537
 NAG  A1405 ( 4.8A)
None
None
None
None
 1.42A 1ia0B-5szsA:
undetectable		 1ia0B-5szsA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 6 ALA A 810
LYS A 812
ASP A 816
ALA A 817
LEU A1078
 None
 1.11A 1iwhA-5szsA:
undetectable		 1iwhA-5szsA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		3 / 3 ARG A 530
ASP A 393
ASN A 240
 None
NAG  A1405 ( 4.8A)
NAG  A1404 ( 1.8A)
 0.91A 1nbhA-5szsA:
undetectable		 1nbhA-5szsA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		3 / 3 ARG A 530
ASP A 393
ASN A 240
 None
NAG  A1405 ( 4.8A)
NAG  A1404 ( 1.8A)
 0.92A 1nbhD-5szsA:
undetectable		 1nbhD-5szsA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 ILE A 315
LEU A 266
PHE A 402
LEU A 300
ILE A 376
 None
 0.99A 1ra2A-5szsA:
undetectable		 1ra2A-5szsA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 ILE A 315
LEU A 266
PHE A 402
LEU A 300
ILE A 376
 None
 0.98A 1ra8A-5szsA:
undetectable		 1ra8A-5szsA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 ASP A 393
HIS A 542
THR A 319
PRO A 536
GLY A 537
 NAG  A1405 ( 4.8A)
None
None
None
None
 1.42A 1tubB-5szsA:
undetectable		 1tubB-5szsA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 GLY A 594
ALA A 489
THR A 490
ALA A 491
ALA A 583
 None
None
NAG  A1437 ( 4.0A)
None
None
 1.01A 2gluB-5szsA:
undetectable		 2gluB-5szsA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 5 PHE A 563
PHE A 554
PHE A 522
ILE A 507
 None
 1.24A 2v0mD-5szsA:
undetectable		 2v0mD-5szsA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 6 ASP A  67
TYR A 154
PHE A  64
LEU A  25
 None
 0.89A 2w98A-5szsA:
undetectable
2w98B-5szsA:
undetectable		 2w98A-5szsA:
13.99
2w98B-5szsA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 7 THR A 930
ILE A 934
GLY A 931
PHE A 840
 None
 0.69A 2y7wC-5szsA:
undetectable		 2y7wC-5szsA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 8 VAL A 186
LEU A  25
TYR A 204
HIS A 152
 None
 0.99A 3af0A-5szsA:
undetectable		 3af0A-5szsA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 4 THR A 653
VAL A 474
GLY A 637
THR A 638
 None
NAG  A1442 ( 4.3A)
None
None
 1.09A 3cflA-5szsA:
undetectable		 3cflA-5szsA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		3 / 3 THR A 669
SER A 668
PHE A 664
 NAG  A1442 ( 4.7A)
NAG  A1442 ( 3.4A)
None
 0.90A 3d4sA-5szsA:
undetectable		 3d4sA-5szsA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 LEU A 168
ALA A  76
GLY A  80
SER A 172
LEU A 171
 None
 1.23A 3gyqA-5szsA:
undetectable
3gyqB-5szsA:
undetectable		 3gyqA-5szsA:
12.33
3gyqB-5szsA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 ARG A1176
GLY A1146
VAL A1197
GLY A1154
ILE A1192
 None
None
NAG  A1472 ( 3.4A)
None
None
 0.94A 3ku1H-5szsA:
undetectable		 3ku1H-5szsA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 6 PHE A 412
TYR A 298
VAL A 373
PHE A 402
 None
 1.26A 3ltwA-5szsA:
undetectable		 3ltwA-5szsA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 7 TYR A 960
VAL A1173
VAL A1177
ARG A1158
 None
 1.07A 3mssB-5szsA:
undetectable		 3mssB-5szsA:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 9 ASP A 836
ALA A 839
ILE A 934
MET A 937
GLY A 940
 None
 1.02A 3ogpB-5szsA:
undetectable		 3ogpB-5szsA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 5 VAL A 273
ILE A 315
PHE A 326
PHE A 392
 None
 0.90A 3owxB-5szsA:
undetectable		 3owxB-5szsA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 9 PHE A 402
PHE A 342
ILE A 340
GLY A 313
PHE A 412
 None
 1.40A 3t3rB-5szsA:
undetectable		 3t3rB-5szsA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 9 ARG A1182
ALA A1143
GLY A1146
ILE A1147
LEU A1162
 None
 1.14A 3u7sB-5szsA:
undetectable		 3u7sB-5szsA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 8 ASN A 510
LYS A 532
ASN A 506
THR A 490
 NAG  A1434 ( 3.1A)
None
NAG  A1437 ( 1.8A)
NAG  A1437 ( 4.0A)
 1.33A 4d1yA-5szsA:
undetectable
4d1yB-5szsA:
undetectable		 4d1yA-5szsA:
8.68
4d1yB-5szsA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 6 TYR A 544
HIS A 586
TYR A 587
TYR A 528
 None
 1.28A 4df2A-5szsA:
undetectable		 4df2A-5szsA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 ILE A 315
LEU A 266
PHE A 402
LEU A 300
ILE A 376
 None
 0.97A 4ej1A-5szsA:
undetectable		 4ej1A-5szsA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 ILE A 315
LEU A 266
PHE A 402
LEU A 300
ILE A 376
 None
 0.99A 4fhbA-5szsA:
undetectable		 4fhbA-5szsA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 ILE A 315
LEU A 266
PHE A 402
LEU A 300
ILE A 376
 None
 0.96A 4i13A-5szsA:
undetectable		 4i13A-5szsA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 7 VAL A 505
ALA A 489
PHE A 487
TYR A 597
 None
 1.12A 4lb2A-5szsA:
undetectable		 4lb2A-5szsA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 ILE A 315
LEU A 266
PHE A 402
LEU A 300
ILE A 376
 None
 0.96A 4p3rA-5szsA:
undetectable		 4p3rA-5szsA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 5 HIS A1130
VAL A 775
GLU A 776
LYS A1094
 None
 1.32A 4p6vB-5szsA:
undetectable
4p6vE-5szsA:
0.8		 4p6vB-5szsA:
14.90
4p6vE-5szsA:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 5 ILE A 226
PRO A 227
HIS A 152
TYR A 161
 None
 1.25A 4s0vA-5szsA:
undetectable		 4s0vA-5szsA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 12 GLU A 375
GLY A 388
TRP A 235
ALA A 379
THR A 381
 None
None
None
None
NAG  A1405 ( 3.7A)
 0.97A 4uckA-5szsA:
undetectable		 4uckA-5szsA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 7 ASN A 558
PRO A 610
PHE A 560
PHE A 563
 None
 1.28A 4v32A-5szsA:
undetectable		 4v32A-5szsA:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 7 ASN A 558
PRO A 610
PHE A 560
PHE A 563
 None
 1.33A 4v32B-5szsA:
undetectable		 4v32B-5szsA:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 6 LEU A 711
ASN A 713
PRO A 712
ARG A 746
 None
 1.38A 4yv5A-5szsA:
0.8		 4yv5A-5szsA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 7 LEU A 705
TYR A 703
GLY A 693
ALA A 685
 None
 0.87A 5f1aB-5szsA:
1.2		 5f1aB-5szsA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 6 SER A 772
GLY A1110
ASN A1111
ILE A1115
 None
None
NAG  A1464 ( 1.8A)
None
 1.13A 5j4nA-5szsA:
undetectable		 5j4nA-5szsA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 7 PHE A 734
ALA A 685
GLY A 457
TYR A 687
 None
 1.04A 5uxdA-5szsA:
undetectable		 5uxdA-5szsA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 10 LEU A 151
THR A 159
ILE A 144
ILE A  89
ILE A 105
 None
 0.97A 6ebpD-5szsA:
undetectable		 6ebpD-5szsA:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 11 LEU A 151
THR A 159
ILE A 144
ILE A  89
ILE A 105
 None
 0.92A 6ebzA-5szsA:
undetectable		 6ebzA-5szsA:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 11 LEU A 151
THR A 159
ILE A 144
ILE A  89
ILE A 105
 None
 0.94A 6ebzB-5szsA:
undetectable		 6ebzB-5szsA:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 11 LEU A 151
THR A 159
ILE A 144
ILE A  89
ILE A 105
 None
 0.94A 6ebzC-5szsA:
undetectable		 6ebzC-5szsA:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 11 LEU A 151
THR A 159
ILE A 144
ILE A  89
ILE A 105
 None
 0.95A 6ebzD-5szsA:
undetectable		 6ebzD-5szsA:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 11 LEU A 151
THR A 159
ILE A 144
ILE A  89
ILE A 105
 None
 1.00A 6gp2A-5szsA:
undetectable		 6gp2A-5szsA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		5 / 11 LEU A 151
THR A 159
ILE A 144
ILE A  89
ILE A 105
 None
 0.97A 6gp2B-5szsA:
undetectable		 6gp2B-5szsA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5szs SPIKE GLYCOPROTEIN
(Human
coronavirus
NL63) 		4 / 5 GLY A  31
LEU A  30
SER A 219
GLN A 221
 None
 1.35A 6ji6A-5szsA:
undetectable		 6ji6A-5szsA:
9.93