SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5szu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B0W_B_DGXB1_2 (NUCLEAR RECEPTOR ROR-GAMMA)	5szu	ACYL-COA HYDROLASE (Neisseria meningitidis)	3 / 3	LEU A 7 VAL A 41 ARG A 48	None	0.84A	3b0wB-5szuA: undetectable	3b0wB-5szuA: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_A_ADNA501_2 (ADENOSYLHOMOCYSTEINA SE)	5szu	ACYL-COA HYDROLASE (Neisseria meningitidis)	4 / 5	GLU A 140 GLU A 89 THR A 113 LEU A 150	None None None COA A 201 (-4.4A)	1.11A	5hm8A-5szuA: undetectable	5hm8A-5szuA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_B_ADNB501_2 (ADENOSYLHOMOCYSTEINA SE)	5szu	ACYL-COA HYDROLASE (Neisseria meningitidis)	4 / 5	GLU A 140 GLU A 89 THR A 113 LEU A 150	None None None COA A 201 (-4.4A)	1.12A	5hm8B-5szuA: undetectable	5hm8B-5szuA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_C_ADNC501_2 (ADENOSYLHOMOCYSTEINA SE)	5szu	ACYL-COA HYDROLASE (Neisseria meningitidis)	4 / 5	GLU A 140 GLU A 89 THR A 113 LEU A 150	None None None COA A 201 (-4.4A)	1.12A	5hm8C-5szuA: undetectable	5hm8C-5szuA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_D_ADND501_2 (ADENOSYLHOMOCYSTEINA SE)	5szu	ACYL-COA HYDROLASE (Neisseria meningitidis)	4 / 5	GLU A 140 GLU A 89 THR A 113 LEU A 150	None None None COA A 201 (-4.4A)	1.11A	5hm8D-5szuA: undetectable	5hm8D-5szuA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_E_ADNE501_2 (ADENOSYLHOMOCYSTEINA SE)	5szu	ACYL-COA HYDROLASE (Neisseria meningitidis)	4 / 5	GLU A 140 GLU A 89 THR A 113 LEU A 150	None None None COA A 201 (-4.4A)	1.11A	5hm8E-5szuA: undetectable	5hm8E-5szuA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_F_ADNF501_2 (ADENOSYLHOMOCYSTEINA SE)	5szu	ACYL-COA HYDROLASE (Neisseria meningitidis)	4 / 5	GLU A 140 GLU A 89 THR A 113 LEU A 150	None None None COA A 201 (-4.4A)	1.12A	5hm8F-5szuA: undetectable	5hm8F-5szuA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_G_ADNG501_2 (ADENOSYLHOMOCYSTEINA SE)	5szu	ACYL-COA HYDROLASE (Neisseria meningitidis)	4 / 5	GLU A 140 GLU A 89 THR A 113 LEU A 150	None None None COA A 201 (-4.4A)	1.20A	5hm8G-5szuA: undetectable	5hm8G-5szuA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_H_ADNH501_2 (ADENOSYLHOMOCYSTEINA SE)	5szu	ACYL-COA HYDROLASE (Neisseria meningitidis)	4 / 5	GLU A 140 GLU A 89 THR A 113 LEU A 150	None None None COA A 201 (-4.4A)	1.12A	5hm8H-5szuA: undetectable	5hm8H-5szuA: 15.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3B0W_B_DGXB1_2","NUCLEAR RECEPTOR ROR-GAMMA","5szu","ACYL-COA HYDROLASE","Neisseria meningitidis",3,"LEU A   7;VAL A  41;ARG A  48","None","0.84A","3b0wB-5szuA:undetectable","3b0wB-5szuA:20.25"],["5HM8_A_ADNA501_2","ADENOSYLHOMOCYSTEINASE","5szu","ACYL-COA HYDROLASE","Neisseria meningitidis",4,"GLU A 140;GLU A  89;THR A 113;LEU A 150","None;None;None;COA A 201 (-4.4A)","1.11A","5hm8A-5szuA:undetectable","5hm8A-5szuA:15.49"],["5HM8_B_ADNB501_2","ADENOSYLHOMOCYSTEINASE","5szu","ACYL-COA HYDROLASE","Neisseria meningitidis",4,"GLU A 140;GLU A  89;THR A 113;LEU A 150","None;None;None;COA A 201 (-4.4A)","1.12A","5hm8B-5szuA:undetectable","5hm8B-5szuA:15.49"],["5HM8_C_ADNC501_2","ADENOSYLHOMOCYSTEINASE","5szu","ACYL-COA HYDROLASE","Neisseria meningitidis",4,"GLU A 140;GLU A  89;THR A 113;LEU A 150","None;None;None;COA A 201 (-4.4A)","1.12A","5hm8C-5szuA:undetectable","5hm8C-5szuA:15.49"],["5HM8_D_ADND501_2","ADENOSYLHOMOCYSTEINASE","5szu","ACYL-COA HYDROLASE","Neisseria meningitidis",4,"GLU A 140;GLU A  89;THR A 113;LEU A 150","None;None;None;COA A 201 (-4.4A)","1.11A","5hm8D-5szuA:undetectable","5hm8D-5szuA:15.49"],["5HM8_E_ADNE501_2","ADENOSYLHOMOCYSTEINASE","5szu","ACYL-COA HYDROLASE","Neisseria meningitidis",4,"GLU A 140;GLU A  89;THR A 113;LEU A 150","None;None;None;COA A 201 (-4.4A)","1.11A","5hm8E-5szuA:undetectable","5hm8E-5szuA:15.49"],["5HM8_F_ADNF501_2","ADENOSYLHOMOCYSTEINASE","5szu","ACYL-COA HYDROLASE","Neisseria meningitidis",4,"GLU A 140;GLU A  89;THR A 113;LEU A 150","None;None;None;COA A 201 (-4.4A)","1.12A","5hm8F-5szuA:undetectable","5hm8F-5szuA:15.49"],["5HM8_G_ADNG501_2","ADENOSYLHOMOCYSTEINASE","5szu","ACYL-COA HYDROLASE","Neisseria meningitidis",4,"GLU A 140;GLU A  89;THR A 113;LEU A 150","None;None;None;COA A 201 (-4.4A)","1.20A","5hm8G-5szuA:undetectable","5hm8G-5szuA:15.49"],["5HM8_H_ADNH501_2","ADENOSYLHOMOCYSTEINASE","5szu","ACYL-COA HYDROLASE","Neisseria meningitidis",4,"GLU A 140;GLU A  89;THR A 113;LEU A 150","None;None;None;COA A 201 (-4.4A)","1.12A","5hm8H-5szuA:undetectable","5hm8H-5szuA:15.49"]]