SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5szw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
5szw ELAV-LIKE PROTEIN 1
(Homo
sapiens)
3 / 3 PRO A  30
LEU A  29
GLN A  35
None
0.58A 4pevB-5szwA:
undetectable
4pevB-5szwA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_B_6T0B913_0
(TOLL-LIKE RECEPTOR 7)
5szw ELAV-LIKE PROTEIN 1
(Homo
sapiens)
5 / 9 TYR A  70
VAL A  68
PHE A  42
THR A  82
ILE A  93
None
1.18A 5zsfA-5szwA:
undetectable
5zsfB-5szwA:
undetectable
5zsfA-5szwA:
20.00
5zsfB-5szwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_A_LLLA302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)
5szw ELAV-LIKE PROTEIN 1
(Homo
sapiens)
5 / 10 TYR A  70
ASP A  75
GLY A  46
ASP A   9
THR A  82
None
1.39A 6mn1A-5szwA:
undetectable
6mn1A-5szwA:
20.37