SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t00'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 5t00 TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		4 / 5 HIS A 425
CYH A 409
ILE A 411
HIS A 430
 ZN  A 504 (-3.2A)
ZN  A 504 (-2.2A)
ZN  A 504 ( 4.8A)
ZN  A 504 (-3.1A)
 1.42A 3qpkA-5t00A:
undetectable		 3qpkA-5t00A:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB601_0
(LACCASE-1)		 5t00 TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		4 / 4 HIS A 425
CYH A 409
ILE A 411
HIS A 430
 ZN  A 504 (-3.2A)
ZN  A 504 (-2.2A)
ZN  A 504 ( 4.8A)
ZN  A 504 (-3.1A)
 1.41A 3qpkB-5t00A:
undetectable		 3qpkB-5t00A:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5t00 TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		4 / 8 TYR A 358
CYH A 353
CYH A 356
ILE A 370
 None
ZN  A 502 (-2.2A)
ZN  A 502 (-2.3A)
None
 1.23A 4bqtC-5t00A:
undetectable
4bqtD-5t00A:
undetectable		 4bqtC-5t00A:
19.72
4bqtD-5t00A:
19.72