SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5t06 ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 7 TYR A  28
THR A  17
LEU A  76
VAL A  12
 None
 0.95A 2cppA-5t06A:
undetectable		 2cppA-5t06A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 5t06 ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		3 / 3 ARG A  54
ARG A 122
PRO A 116
 None
 1.06A 2wljA-5t06A:
undetectable		 2wljA-5t06A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5t06 ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 8 TYR A  28
THR A  17
LEU A  76
VAL A  12
 None
 0.92A 4l4dA-5t06A:
undetectable		 4l4dA-5t06A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5t06 ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 8 TYR A  28
THR A  17
LEU A  76
VAL A  12
 None
 0.91A 4l4eA-5t06A:
undetectable		 4l4eA-5t06A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5t06 ACYL-COA THIOESTER
HYDROLASE YBGC
(Escherichia
coli) 		4 / 8 TYR A  28
THR A  17
LEU A  76
VAL A  12
 None
 0.93A 4l4fA-5t06A:
undetectable		 4l4fA-5t06A:
14.73