SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t09'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		4 / 4 ILE A  65
LEU A  97
VAL A 137
ILE A 135
 None
 0.68A 1fm6D-5t09A:
undetectable		 1fm6D-5t09A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		3 / 3 TRP A 119
PHE A  84
TRP A 112
 None
 1.18A 1r15C-5t09A:
undetectable		 1r15C-5t09A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		3 / 3 TRP A 119
PHE A  84
TRP A 112
 None
 1.17A 1r15F-5t09A:
undetectable		 1r15F-5t09A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		3 / 3 TRP A 119
PHE A  84
TRP A 112
 None
 1.17A 1r15G-5t09A:
undetectable		 1r15G-5t09A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		3 / 3 TRP A 119
PHE A  84
TRP A 112
 None
 1.18A 1r15H-5t09A:
undetectable		 1r15H-5t09A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		3 / 3 ARG A  30
ARG A  33
ILE A 232
 None
 0.63A 1uobA-5t09A:
undetectable		 1uobA-5t09A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		5 / 10 LEU A  72
VAL A  77
GLY A  76
LEU A  40
ALA A  44
 None
 0.97A 2v3kA-5t09A:
undetectable		 2v3kA-5t09A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		3 / 3 SER A 124
GLU A 109
ASP A 121
 None
 0.84A 3bwyA-5t09A:
undetectable		 3bwyA-5t09A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		4 / 5 ASP A 238
THR A 216
LEU A 215
LYS A  58
 None
 1.37A 4a3pA-5t09A:
undetectable		 4a3pA-5t09A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_B_QI9B602_0
(CYTOCHROME P450 2D6)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		5 / 9 PHE A  93
LEU A  80
SER A 138
VAL A 123
VAL A 104
 None
 1.47A 4wnvB-5t09A:
undetectable		 4wnvB-5t09A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		3 / 3 THR A  66
HIS A 106
LEU A 120
 None
 0.76A 5axdA-5t09A:
undetectable		 5axdA-5t09A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		4 / 5 ILE A  65
ILE A 135
HIS A 131
VAL A 137
 None
 1.01A 5jmnA-5t09A:
undetectable		 5jmnA-5t09A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 5t09 TYPE III SECRETION
SYSTEM EFFECTOR
HOPBA1
(Pseudomonas
syringae) 		5 / 12 ALA A 191
GLY A  53
LYS A  63
GLU A  67
LEU A  40
 None
 1.17A 5nwuA-5t09A:
undetectable		 5nwuA-5t09A:
10.55