SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 5t0v FRATAXIN HOMOLOG,
MITOCHONDRIAL
IRON SULFUR CLUSTER
ASSEMBLY PROTEIN 1,
MITOCHONDRIAL
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 6 PRO A 100
ALA A 169
GLU a 129
GLU A 165
 None
 1.34A 1qhyA-5t0vA:
undetectable		 1qhyA-5t0vA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5t0v IRON SULFUR CLUSTER
ASSEMBLY PROTEIN 1,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 12 ALA a 150
LEU a  75
MET a  73
ALA a 143
ILE a 121
 None
 1.08A 3ut5B-5t0va:
undetectable		 3ut5B-5t0va:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 5t0v IRON SULFUR CLUSTER
ASSEMBLY PROTEIN 1,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 12 ALA a 150
LEU a  75
MET a  73
ALA a 143
ILE a 121
 None
 1.05A 4o2bB-5t0va:
undetectable		 4o2bB-5t0va:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 5t0v FRATAXIN HOMOLOG,
MITOCHONDRIAL
IRON SULFUR CLUSTER
ASSEMBLY PROTEIN 1,
MITOCHONDRIAL
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 LYS a  32
ARG a  33
HIS A  95
 None
 1.12A 4zbrA-5t0va:
undetectable		 4zbrA-5t0va:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 5t0v IRON SULFUR CLUSTER
ASSEMBLY PROTEIN 1,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 12 ALA a 150
LEU a  75
MET a  73
ALA a 143
ILE a 121
 None
 1.09A 5itzB-5t0va:
undetectable		 5itzB-5t0va:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5t0v IRON SULFUR CLUSTER
ASSEMBLY PROTEIN 1,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 12 ALA a 150
LEU a  75
MET a  73
ALA a 143
ILE a 121
 None
 1.04A 5mioB-5t0va:
undetectable		 5mioB-5t0va:
15.06