SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 8 PHE A 159
LEU A 114
ALA A   3
VAL A  98
 None
 0.73A 1epbB-5t13A:
undetectable		 1epbB-5t13A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 4 ILE A 340
ARG A 273
ASP A 265
ASN A 312
 None
 1.41A 1nbiD-5t13A:
undetectable		 1nbiD-5t13A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 7 ASP A 216
VAL A 218
GLY A 201
ILE A 202
 None
 0.83A 1t7iB-5t13A:
undetectable		 1t7iB-5t13A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 7 ASP A 216
VAL A 218
GLY A 201
ILE A 202
 None
 0.82A 1t7jB-5t13A:
undetectable		 1t7jB-5t13A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 12 GLY A 360
ALA A 302
ASP A 265
ALA A 266
ARG A 311
 MG  A 403 (-4.5A)
None
None
None
None
 1.41A 2avdB-5t13A:
undetectable		 2avdB-5t13A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 9 GLN A 118
PHE A 120
ILE A  80
PHE A  79
PHE A  62
 None
 1.41A 2dr6A-5t13A:
0.4		 2dr6A-5t13A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 12 PHE A 120
PHE A  96
ILE A 258
PHE A 159
ALA A 145
 None
 1.01A 2j0dA-5t13A:
undetectable		 2j0dA-5t13A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 8 ILE A 244
TYR A 347
VAL A 162
CYH A  35
 None
 0.88A 2xz5A-5t13A:
undetectable
2xz5C-5t13A:
undetectable		 2xz5A-5t13A:
20.00
2xz5C-5t13A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 8 ILE A 244
TYR A 347
VAL A 162
CYH A  35
 None
 0.87A 2xz5C-5t13A:
undetectable
2xz5D-5t13A:
undetectable		 2xz5C-5t13A:
20.00
2xz5D-5t13A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		3 / 3 TYR A 223
GLU A 303
THR A 232
 None
MG  A 403 (-3.4A)
None
 0.78A 2y7hB-5t13A:
undetectable		 2y7hB-5t13A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 9 ALA A  57
VAL A  36
ILE A  23
PHE A  62
THR A  54
 None
 1.15A 3freX-5t13A:
undetectable		 3freX-5t13A:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 12 TYR A 193
GLY A 192
GLU A 353
SER A 352
ALA A 234
 None
None
None
MG  A 403 (-2.9A)
None
 1.13A 3id6C-5t13A:
undetectable		 3id6C-5t13A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 8 ASP A 216
VAL A 218
GLY A 201
ILE A 202
 None
 0.78A 3nu9A-5t13A:
undetectable		 3nu9A-5t13A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 8 TYR A 347
VAL A 162
CYH A  35
ILE A 244
 None
 1.07A 4aftD-5t13A:
undetectable
4aftE-5t13A:
undetectable		 4aftD-5t13A:
19.74
4aftE-5t13A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 8 TYR A 347
VAL A 162
CYH A  35
ILE A 244
 None
 1.16A 4bqtC-5t13A:
undetectable
4bqtD-5t13A:
undetectable		 4bqtC-5t13A:
19.74
4bqtD-5t13A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 12 VAL A 298
GLY A 269
ILE A 337
ILE A 340
LEU A 276
 None
 1.02A 4iv0A-5t13A:
undetectable		 4iv0A-5t13A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 8 ILE A 151
ALA A 205
GLU A 208
VAL A 245
 None
 0.72A 4jltA-5t13A:
undetectable		 4jltA-5t13A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 12 VAL A 298
GLY A 269
ILE A 337
ILE A 340
LEU A 276
 None
 1.02A 4mwzB-5t13A:
undetectable		 4mwzB-5t13A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 12 ASN A 324
GLY A  83
GLY A  84
GLY A  52
ASN A  47
 None
CO2  A 401 (-4.5A)
None
CO2  A 402 ( 4.2A)
None
 0.98A 4obwB-5t13A:
undetectable		 4obwB-5t13A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 7 GLU A 208
SER A 227
ILE A 202
VAL A 160
 None
 0.94A 4tvtA-5t13A:
undetectable		 4tvtA-5t13A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		3 / 3 LEU A 166
ARG A 195
ARG A  51
 None
None
CO2  A 402 (-4.3A)
 0.89A 4yiaB-5t13A:
undetectable		 4yiaB-5t13A:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 7 ALA A 109
GLY A 280
THR A 288
ARG A 113
 None
 0.80A 5btdA-5t13A:
undetectable
5btdB-5t13A:
undetectable
5btdC-5t13A:
undetectable		 5btdA-5t13A:
22.99
5btdB-5t13A:
22.89
5btdC-5t13A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 7 ARG A 113
ALA A 109
GLY A 280
THR A 288
 None
 0.85A 5btdA-5t13A:
undetectable
5btdC-5t13A:
undetectable
5btdD-5t13A:
undetectable		 5btdA-5t13A:
22.99
5btdC-5t13A:
22.99
5btdD-5t13A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 12 ALA A  20
VAL A  19
PHE A  58
ALA A  14
TYR A  53
 None
 1.07A 5n5dA-5t13A:
undetectable		 5n5dA-5t13A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 12 ALA A  20
VAL A  19
PHE A  58
ALA A  14
TYR A  53
 None
 1.05A 5n5dB-5t13A:
undetectable		 5n5dB-5t13A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		5 / 12 LEU A  22
ILE A  28
VAL A  36
CYH A  35
PHE A  62
 None
 1.26A 5vlmE-5t13A:
undetectable		 5vlmE-5t13A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5t13 CYANURIC ACID
AMIDOHYDROLASE
(Enterobacter
cloacae) 		4 / 6 MET A 132
ALA A 203
LEU A 204
ALA A 139
 None
 1.20A 6fosB-5t13A:
undetectable		 6fosB-5t13A:
13.58