SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5t1d GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		3 / 3 GLN C  92
TYR C 167
ARG C 168
 None
 0.96A 1gtbA-5t1dC:
undetectable		 1gtbA-5t1dC:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5t1d GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		3 / 3 THR C  84
GLU C 207
HIS C 191
 None
 0.83A 1xwfA-5t1dC:
undetectable		 1xwfA-5t1dC:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5t1d GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		3 / 3 THR C  84
GLU C 207
HIS C 191
 None
 0.83A 1xwfB-5t1dC:
undetectable		 1xwfB-5t1dC:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5t1d GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		3 / 3 THR C  84
GLU C 207
HIS C 191
 None
 0.81A 1xwfC-5t1dC:
undetectable		 1xwfC-5t1dC:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5t1d GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		3 / 3 THR C  84
GLU C 207
HIS C 191
 None
 0.79A 1xwfD-5t1dC:
undetectable		 1xwfD-5t1dC:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 5t1d GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		4 / 6 TYR C 117
TYR C 142
PHE C 129
LEU C 177
 None
 1.13A 2w98A-5t1dC:
undetectable
2w98B-5t1dC:
undetectable		 2w98A-5t1dC:
18.10
2w98B-5t1dC:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5t1d GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		3 / 3 TRP C 163
VAL C 166
TRP C 125
 None
 1.25A 3zq8C-5t1dC:
undetectable
3zq8D-5t1dC:
undetectable		 3zq8C-5t1dC:
7.58
3zq8D-5t1dC:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 5t1d GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		5 / 12 LEU C 149
GLY C 143
VAL C 195
PRO C 202
GLY C 172
 None
 1.13A 5f9zA-5t1dC:
undetectable		 5f9zA-5t1dC:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5t1d E1D1 IGG2A HEAVY
CHAIN
(Mus
musculus) 		3 / 3 VAL H 185
SER H 187
TRP H 190
 None
 1.03A 5jwaA-5t1dH:
undetectable		 5jwaA-5t1dH:
17.01