SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 4 ARG A 292
ALA A 361
ALA A 349
GLU A 352
 None
 1.10A 1e7bB-5t1qA:
1.8		 1e7bB-5t1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 SER A 355
ALA A 349
PHE A 369
ILE A 350
 None
 1.03A 1gm7A-5t1qA:
undetectable
1gm7B-5t1qA:
undetectable		 1gm7A-5t1qA:
20.22
1gm7B-5t1qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.15A 1p6kA-5t1qA:
undetectable		 1p6kA-5t1qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.15A 1p6kB-5t1qA:
undetectable		 1p6kB-5t1qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.10A 1rs6A-5t1qA:
undetectable		 1rs6A-5t1qA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.16A 1rs7B-5t1qA:
undetectable		 1rs7B-5t1qA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 6 ALA A 349
LEU A 351
ILE A 462
SER A 355
 None
 0.99A 1sbrA-5t1qA:
undetectable
1sbrB-5t1qA:
undetectable		 1sbrA-5t1qA:
20.56
1sbrB-5t1qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 7 ARG A 321
HIS A 465
TYR A 482
ILE A 350
 None
 1.44A 1tdnA-5t1qA:
undetectable		 1tdnA-5t1qA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		5 / 11 ARG A 500
SER A 317
VAL A 314
ILE A 462
HIS A 510
 None
 1.43A 1vhwA-5t1qA:
undetectable
1vhwD-5t1qA:
undetectable		 1vhwA-5t1qA:
20.79
1vhwD-5t1qA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		5 / 11 ARG A 500
SER A 317
VAL A 314
ILE A 462
HIS A 510
 None
 1.46A 1vhwC-5t1qA:
undetectable
1vhwE-5t1qA:
undetectable		 1vhwC-5t1qA:
20.79
1vhwE-5t1qA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		5 / 11 HIS A 510
ARG A 500
SER A 317
VAL A 314
ILE A 462
 None
 1.46A 1vhwA-5t1qA:
undetectable
1vhwD-5t1qA:
undetectable		 1vhwA-5t1qA:
20.79
1vhwD-5t1qA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		5 / 11 HIS A 510
ARG A 500
SER A 317
VAL A 314
ILE A 462
 None
 1.44A 1vhwC-5t1qA:
undetectable
1vhwE-5t1qA:
undetectable		 1vhwC-5t1qA:
20.79
1vhwE-5t1qA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.18A 1zzqA-5t1qA:
undetectable		 1zzqA-5t1qA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.11A 1zzuA-5t1qA:
undetectable		 1zzuA-5t1qA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.17A 1zzuB-5t1qA:
undetectable		 1zzuB-5t1qA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		3 / 3 CYH A 513
PRO A 509
ASP A 534
 None
 0.79A 3hlwB-5t1qA:
undetectable		 3hlwB-5t1qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.12A 3n62A-5t1qA:
undetectable		 3n62A-5t1qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.12A 3n62B-5t1qA:
undetectable		 3n62B-5t1qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.18A 3n66B-5t1qA:
undetectable		 3n66B-5t1qA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		5 / 10 VAL A 315
PHE A 297
SER A 353
ILE A 462
TYR A 466
 None
 1.27A 3um5A-5t1qA:
undetectable		 3um5A-5t1qA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		5 / 10 VAL A 315
PHE A 297
SER A 353
ILE A 462
TYR A 466
 None
 1.30A 3um5B-5t1qA:
undetectable		 3um5B-5t1qA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		5 / 9 LEU A 468
ALA A 331
ASP A 330
LEU A 368
ILE A 346
 None
 1.47A 3wsjA-5t1qA:
undetectable		 3wsjA-5t1qA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 7 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.14A 4kcnB-5t1qA:
undetectable		 4kcnB-5t1qA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		3 / 3 CYH A 513
PRO A 509
ASP A 534
 None
 0.84A 4pm5A-5t1qA:
undetectable		 4pm5A-5t1qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		5 / 11 SER A 317
THR A 320
ALA A 359
GLU A 352
GLU A 501
 None
 1.30A 4zjoD-5t1qA:
undetectable		 4zjoD-5t1qA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		5 / 10 ALA A 557
ILE A 616
TYR A 547
SER A 527
VAL A 575
 None
 1.21A 5i6xA-5t1qA:
undetectable		 5i6xA-5t1qA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		4 / 8 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.24A 5vunA-5t1qA:
undetectable		 5vunA-5t1qA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979
(Staphylococcus
aureus) 		3 / 3 ARG A 400
PHE A 399
GLY A 373
 None
 0.62A 6fgdA-5t1qA:
undetectable		 6fgdA-5t1qA:
19.34