SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		5 / 12 PHE A  74
LEU A  56
LEU A  47
VAL A 126
LEU A  24
 None
 1.15A 2bxfA-5t3pA:
undetectable		 2bxfA-5t3pA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 8 THR A 123
PRO A 124
SER A  42
ALA A  87
 None
 0.94A 2v32A-5t3pA:
undetectable
2v32B-5t3pA:
undetectable		 2v32A-5t3pA:
20.08
2v32B-5t3pA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 8 THR A 123
PRO A 124
SER A  42
ALA A  87
 None
 0.97A 2v41G-5t3pA:
undetectable
2v41H-5t3pA:
undetectable		 2v41G-5t3pA:
20.08
2v41H-5t3pA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 4 GLN A 136
PRO A 137
VAL A  98
GLU A 141
 None
 1.35A 3huoA-5t3pA:
undetectable		 3huoA-5t3pA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 4 ASP A  80
ASP A  83
GLY A  77
THR A 123
 None
 0.91A 3tl9B-5t3pA:
undetectable		 3tl9B-5t3pA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 6 TYR A  33
PRO A 113
TYR A  38
LEU A  36
 None
 1.32A 5bmvB-5t3pA:
undetectable		 5bmvB-5t3pA:
18.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 4 VAL A  60
VAL A  72
TYR A 187
GLN A 188
 None
 0.35A 5qggA-5t3pA:
29.1		 5qggA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.31A 5qgjA-5t3pA:
28.5		 5qgjA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  72
TYR A 187
GLN A 188
 None
 0.30A 5qgkA-5t3pA:
28.5		 5qgkA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.33A 5qgmA-5t3pA:
29.0		 5qgmA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.34A 5qgnA-5t3pA:
28.3		 5qgnA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 4 VAL A  60
VAL A  72
TYR A 187
GLN A 188
 None
 0.31A 5qgoA-5t3pA:
29.0		 5qgoA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 4 VAL A  60
VAL A  72
TYR A 187
GLN A 188
 None
 0.36A 5qgpA-5t3pA:
28.8		 5qgpA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 4 VAL A  60
VAL A  72
TYR A 187
GLN A 188
 None
 0.47A 5qgqA-5t3pA:
28.7		 5qgqA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  72
TYR A 187
GLN A 188
 None
 0.34A 5qgrA-5t3pA:
28.4		 5qgrA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  72
TYR A 187
GLN A 188
 None
 0.26A 5qgtA-5t3pA:
28.8		 5qgtA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.42A 5qgyA-5t3pA:
28.3		 5qgyA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.43A 5qgzA-5t3pA:
28.4		 5qgzA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.41A 5qh0A-5t3pA:
28.5		 5qh0A-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.44A 5qh2A-5t3pA:
28.5		 5qh2A-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.42A 5qh3A-5t3pA:
28.4		 5qh3A-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.40A 5qh5A-5t3pA:
28.4		 5qh5A-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.41A 5qh6A-5t3pA:
28.4		 5qh6A-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.39A 5qh7A-5t3pA:
28.5		 5qh7A-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 CYH A 114
MET A 192
ASN A 195
 None
 0.30A 5qh8A-5t3pA:
29.0		 5qh8A-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.45A 5qhaA-5t3pA:
28.8		 5qhaA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 4 VAL A  60
VAL A  72
TYR A 187
GLN A 188
 None
 0.41A 5qhbA-5t3pA:
28.8		 5qhbA-5t3pA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		3 / 3 VAL A  60
VAL A  72
GLN A 188
 None
 0.39A 5qhhA-5t3pA:
28.2		 5qhhA-5t3pA:
93.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 5 LEU A  24
VAL A 108
GLU A 106
LEU A 128
 None
EDO  A 302 (-4.6A)
None
None
 0.95A 5xooB-5t3pA:
undetectable		 5xooB-5t3pA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens) 		4 / 4 GLY A 127
LEU A 128
VAL A 108
GLU A 106
 None
None
EDO  A 302 (-4.6A)
None
 1.22A 5yw0A-5t3pA:
undetectable		 5yw0A-5t3pA:
24.91