SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t3t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 5t3t FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Zaire
ebolavirus) 		4 / 8 TYR A 211
LEU A 235
PHE A 238
LEU A 171
 None
 1.07A 1e7cA-5t3tA:
2.4		 1e7cA-5t3tA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 5t3t FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Zaire
ebolavirus) 		4 / 4 LEU A 249
PRO A 250
LEU A 188
ARG A 195
 None
 1.02A 2hrcA-5t3tA:
undetectable		 2hrcA-5t3tA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5t3t FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Zaire
ebolavirus) 		4 / 4 LEU A 249
PRO A 250
LEU A 188
ARG A 195
 None
 0.99A 2hrcB-5t3tA:
undetectable		 2hrcB-5t3tA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5t3t FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Zaire
ebolavirus) 		4 / 4 LEU A 249
PRO A 250
LEU A 188
ARG A 195
 None
 1.00A 2pnjB-5t3tA:
undetectable		 2pnjB-5t3tA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5t3t FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Zaire
ebolavirus) 		4 / 4 LEU A 249
PRO A 250
LEU A 188
ARG A 195
 None
 0.88A 3hcoB-5t3tA:
undetectable		 3hcoB-5t3tA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 5t3t FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Zaire
ebolavirus) 		4 / 8 PHE A 242
ALA A 155
PHE A 181
ASN A 244
 None
 1.11A 3t3sE-5t3tA:
undetectable		 3t3sE-5t3tA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5t3t FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Zaire
ebolavirus) 		4 / 6 TRP A 230
GLY A 220
ALA A 225
LEU A 226
 None
 0.75A 6fosA-5t3tA:
undetectable		 6fosA-5t3tA:
18.13