SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 5t3w FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Marburg
marburgvirus) 		4 / 4 HIS A 200
LEU A 233
LEU A 178
LEU A 161
 None
 1.21A 1a4lD-5t3wA:
undetectable		 1a4lD-5t3wA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5t3w FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Marburg
marburgvirus) 		4 / 6 TRP A 237
GLY A 212
GLY A 220
PHE A 245
 None
 0.87A 2qx6A-5t3wA:
undetectable
2qx6B-5t3wA:
undetectable		 2qx6A-5t3wA:
21.51
2qx6B-5t3wA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5t3w FUSION PROTEIN OF
NUCLEOPROTEIN AND
MINOR NUCLEOPROTEIN
VP30
(Marburg
marburgvirus) 		4 / 6 TRP A 237
GLY A 227
ALA A 232
LEU A 233
 None
 0.86A 6fosA-5t3wA:
undetectable		 6fosA-5t3wA:
16.85