SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t3x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5t3x IOMA HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ASN D  52
PRO D  52
PHE D  78
TYR D  59
 None
 1.38A 5amhA-5t3xD:
undetectable		 5amhA-5t3xD:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5t3x IOMA HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER D 188
GLY D 134
THR D 135
ALA D 136
THR D 131
 None
 1.13A 5bxnH-5t3xD:
undetectable
5bxnI-5t3xD:
undetectable		 5bxnH-5t3xD:
20.93
5bxnI-5t3xD:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5t3x IOMA HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL D 207
THR D 205
VAL D 211
GLY D 118
VAL D 152
 None
 1.01A 6drzA-5t3xD:
undetectable		 6drzA-5t3xD:
18.98