SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 5t3y TWO-COMPONENT SYSTEM
RESPONSE REGULATOR
(Burkholderia
multivorans) 		5 / 12 GLY A  38
TYR A  74
ALA A  33
ASP A  40
ALA A  37
 None
 1.38A 2avdB-5t3yA:
undetectable		 2avdB-5t3yA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 5t3y TWO-COMPONENT SYSTEM
RESPONSE REGULATOR
(Burkholderia
multivorans) 		5 / 12 GLY A  86
ASP A  53
ILE A  65
PRO A  57
ASN A  55
 None
 1.19A 3eeoA-5t3yA:
undetectable		 3eeoA-5t3yA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 5t3y TWO-COMPONENT SYSTEM
RESPONSE REGULATOR
(Burkholderia
multivorans) 		4 / 4 VAL A 111
LEU A 112
LEU A  18
ASP A   9
 None
 1.40A 5xv7A-5t3yA:
undetectable		 5xv7A-5t3yA:
19.35