SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t43'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F8Y_A_X6XA202_1 (GALNAC/GAL-SPECIFIC LECTIN)	5t43	LIPOCALIN-1 (Homo sapiens)	4 / 8	HIS A 84 GLY A 82 GLY A 81 VAL A 85	None	0.64A	5f8yA-5t43A: undetectable	5f8yA-5t43A: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFIC LECTIN)	5t43	LIPOCALIN-1 (Homo sapiens)	4 / 8	HIS A 84 GLY A 82 GLY A 81 VAL A 85	None	0.68A	5f8yB-5t43A: undetectable	5f8yB-5t43A: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_I_PCFI101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	5t43	LIPOCALIN-1 (Homo sapiens)	5 / 11	SER A 58 VAL A 24 GLY A 112 SER A 101 ALA A 86	None	1.19A	6hu9A-5t43A: undetectable 6hu9E-5t43A: undetectable 6hu9I-5t43A: undetectable	6hu9A-5t43A: 19.71 6hu9E-5t43A: 22.40 6hu9I-5t43A: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_T_PCFT101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	5t43	LIPOCALIN-1 (Homo sapiens)	5 / 10	SER A 58 VAL A 24 GLY A 112 SER A 101 ALA A 86	None	1.16A	6hu9L-5t43A: undetectable 6hu9P-5t43A: undetectable 6hu9T-5t43A: undetectable	6hu9L-5t43A: 19.71 6hu9P-5t43A: 22.40 6hu9T-5t43A: 21.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5F8Y_A_X6XA202_1","GALNAC\/GAL-SPECIFIC LECTIN","5t43","LIPOCALIN-1","Homo sapiens",4,"HIS A  84;GLY A  82;GLY A  81;VAL A  85","None","0.64A","5f8yA-5t43A:undetectable","5f8yA-5t43A:18.48"],["5F8Y_B_X6XB201_1","GALNAC\/GAL-SPECIFIC LECTIN","5t43","LIPOCALIN-1","Homo sapiens",4,"HIS A  84;GLY A  82;GLY A  81;VAL A  85","None","0.68A","5f8yB-5t43A:undetectable","5f8yB-5t43A:18.48"],["6HU9_I_PCFI101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","5t43","LIPOCALIN-1","Homo sapiens",5,"SER A  58;VAL A  24;GLY A 112;SER A 101;ALA A  86","None","1.19A","6hu9A-5t43A:undetectable;6hu9E-5t43A:undetectable;6hu9I-5t43A:undetectable","6hu9A-5t43A:19.71;6hu9E-5t43A:22.40;6hu9I-5t43A:21.83"],["6HU9_T_PCFT101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","5t43","LIPOCALIN-1","Homo sapiens",5,"SER A  58;VAL A  24;GLY A 112;SER A 101;ALA A  86","None","1.16A","6hu9L-5t43A:undetectable;6hu9P-5t43A:undetectable;6hu9T-5t43A:undetectable","6hu9L-5t43A:19.71;6hu9P-5t43A:22.40;6hu9T-5t43A:21.83"]]