SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t4z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 5t4z ANTIBODY DH501 FAB
HEAVY CHAIN
(Macaca
mulatta) 		5 / 12 ARG H  66
PRO H  41
LEU H  20
LEU H  18
ASP H  86
 None
 1.32A 1e7wA-5t4zH:
undetectable		 1e7wA-5t4zH:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.09A 1zzrA-5t4zL:
undetectable
1zzrB-5t4zL:
undetectable		 1zzrA-5t4zL:
19.85
1zzrB-5t4zL:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.10A 1zzrA-5t4zL:
undetectable
1zzrB-5t4zL:
undetectable		 1zzrA-5t4zL:
19.85
1zzrB-5t4zL:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.09A 1zzuA-5t4zL:
undetectable
1zzuB-5t4zL:
undetectable		 1zzuA-5t4zL:
19.85
1zzuB-5t4zL:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.08A 1zzuA-5t4zL:
undetectable
1zzuB-5t4zL:
undetectable		 1zzuA-5t4zL:
19.85
1zzuB-5t4zL:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQE_A_ADNA1002_1
(APRATAXIN AND
PNK-LIKE FACTOR)		 5t4z ANTIBODY DH501 FAB
HEAVY CHAIN
ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 5 TYR H 100
SER L  32
CYH L  31
TYR L  91
 None
 1.38A 2kqeA-5t4zH:
undetectable		 2kqeA-5t4zH:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5t4z ANTIBODY DH501 FAB
HEAVY CHAIN
ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		5 / 12 ILE H 100
PHE L  98
ARG H  38
LEU H  80
ILE H  37
 None
 1.28A 2xkwB-5t4zH:
undetectable		 2xkwB-5t4zH:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5t4z ANTIBODY DH501 FAB
HEAVY CHAIN
(Macaca
mulatta) 		5 / 12 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.49A 2y03B-5t4zH:
undetectable		 2y03B-5t4zH:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		3 / 3 THR L 114
SER L 137
PHE L 118
 None
 0.77A 3d4sA-5t4zL:
undetectable		 3d4sA-5t4zL:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.09A 3dqrA-5t4zL:
undetectable
3dqrB-5t4zL:
undetectable		 3dqrA-5t4zL:
19.75
3dqrB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.12A 3dqrA-5t4zL:
undetectable
3dqrB-5t4zL:
undetectable		 3dqrA-5t4zL:
19.75
3dqrB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 4 PRO L   9
THR L 102
GLY L  25
THR L  26
 None
 1.14A 3ib1A-5t4zL:
undetectable		 3ib1A-5t4zL:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.07A 3jx2A-5t4zL:
undetectable
3jx2B-5t4zL:
undetectable		 3jx2A-5t4zL:
19.75
3jx2B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.08A 3jx2A-5t4zL:
undetectable
3jx2B-5t4zL:
undetectable		 3jx2A-5t4zL:
19.75
3jx2B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.11A 3jx3A-5t4zL:
undetectable
3jx3B-5t4zL:
undetectable		 3jx3A-5t4zL:
19.75
3jx3B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.06A 3jx3A-5t4zL:
undetectable
3jx3B-5t4zL:
undetectable		 3jx3A-5t4zL:
19.75
3jx3B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.08A 3jx4A-5t4zL:
undetectable
3jx4B-5t4zL:
undetectable		 3jx4A-5t4zL:
19.75
3jx4B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.09A 3jx5A-5t4zL:
undetectable
3jx5B-5t4zL:
undetectable		 3jx5A-5t4zL:
19.75
3jx5B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.07A 3jx5A-5t4zL:
undetectable
3jx5B-5t4zL:
undetectable		 3jx5A-5t4zL:
19.75
3jx5B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.01A 3jx6A-5t4zL:
undetectable
3jx6B-5t4zL:
undetectable		 3jx6A-5t4zL:
19.75
3jx6B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.02A 3jx6A-5t4zL:
undetectable
3jx6B-5t4zL:
undetectable		 3jx6A-5t4zL:
19.75
3jx6B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBR_A_ASDA129_1
(STEROID
DELTA-ISOMERASE)		 5t4z ANTIBODY DH501 FAB
HEAVY CHAIN
ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		5 / 12 PHE H 166
VAL L 195
VAL L 144
PRO L 113
PHE L 139
 None
 1.39A 3nbrA-5t4zH:
undetectable		 3nbrA-5t4zH:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.02A 3nljA-5t4zL:
undetectable
3nljB-5t4zL:
undetectable		 3nljA-5t4zL:
19.75
3nljB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.02A 3nljA-5t4zL:
undetectable
3nljB-5t4zL:
undetectable		 3nljA-5t4zL:
19.75
3nljB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.06A 3nlpA-5t4zL:
undetectable
3nlpB-5t4zL:
undetectable		 3nlpA-5t4zL:
19.75
3nlpB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.07A 3nlpA-5t4zL:
undetectable
3nlpB-5t4zL:
undetectable		 3nlpA-5t4zL:
19.75
3nlpB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 8 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.05A 3nlqA-5t4zL:
undetectable
3nlqB-5t4zL:
undetectable		 3nlqA-5t4zL:
19.75
3nlqB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.06A 3nlqA-5t4zL:
undetectable
3nlqB-5t4zL:
undetectable		 3nlqA-5t4zL:
19.75
3nlqB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.05A 3nlrA-5t4zL:
undetectable
3nlrB-5t4zL:
undetectable		 3nlrA-5t4zL:
19.75
3nlrB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 8 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.05A 3nlrA-5t4zL:
undetectable
3nlrB-5t4zL:
undetectable		 3nlrA-5t4zL:
19.75
3nlrB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 5t4z ANTIBODY DH501 FAB
HEAVY CHAIN
(Macaca
mulatta) 		4 / 8 THR H  87
PRO H  84
GLY H 174
SER H 113
 None
 1.01A 3tzfB-5t4zH:
undetectable		 3tzfB-5t4zH:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.09A 4cx3A-5t4zL:
undetectable
4cx3B-5t4zL:
undetectable		 4cx3A-5t4zL:
19.75
4cx3B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.07A 4cx3A-5t4zL:
undetectable
4cx3B-5t4zL:
undetectable		 4cx3A-5t4zL:
19.75
4cx3B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.11A 4cx4A-5t4zL:
undetectable
4cx4B-5t4zL:
undetectable		 4cx4A-5t4zL:
19.75
4cx4B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.07A 4cx4A-5t4zL:
undetectable
4cx4B-5t4zL:
undetectable		 4cx4A-5t4zL:
19.75
4cx4B-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 5t4z ANTIBODY DH501 FAB
HEAVY CHAIN
(Macaca
mulatta) 		5 / 10 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.50A 4ldoA-5t4zH:
undetectable		 4ldoA-5t4zH:
19.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 SER L  34
TYR L  36
TYR L  49
PRO L  55
 None
 0.64A 5aclA-5t4zL:
21.3		 5aclA-5t4zL:
62.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.03A 5addA-5t4zL:
undetectable
5addB-5t4zL:
undetectable		 5addA-5t4zL:
19.75
5addB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 0.99A 5adeA-5t4zL:
undetectable
5adeB-5t4zL:
undetectable		 5adeA-5t4zL:
19.75
5adeB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.07A 5g0pA-5t4zL:
undetectable
5g0pB-5t4zL:
undetectable		 5g0pA-5t4zL:
19.75
5g0pB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.07A 5g0pA-5t4zL:
undetectable
5g0pB-5t4zL:
undetectable		 5g0pA-5t4zL:
19.75
5g0pB-5t4zL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 5t4z ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		4 / 6 GLY L  68
THR L  69
SER L  70
GLY L  25
 None
 0.86A 5k4pA-5t4zL:
undetectable		 5k4pA-5t4zL:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5t4z ANTIBODY DH501 FAB
HEAVY CHAIN
ANTIBODY DH501 FAB
LIGHT CHAIN
(Macaca
mulatta) 		5 / 9 SER L 176
SER H 179
SER H 180
GLY H 139
THR L 114
 None
 1.39A 6awpA-5t4zL:
undetectable		 6awpA-5t4zL:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5t4z ANTIBODY DH501 FAB
HEAVY CHAIN
(Macaca
mulatta) 		5 / 12 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.46A 6h7mB-5t4zH:
undetectable		 6h7mB-5t4zH:
17.18