SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 5t51 KLLA0F02343P
KLLA0E05809P
(Kluyveromyces
lactis;
Kluyveromyces
lactis) 		5 / 11 GLU A  33
ALA A  30
ILE A  28
ASP A  25
PHE B  77
 None
 1.35A 2admA-5t51A:
undetectable		 2admA-5t51A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5t51 KLLA0E05809P
(Kluyveromyces
lactis) 		4 / 8 TRP B  69
PHE B  77
ALA B  27
LEU B  28
 None
 1.07A 2o01A-5t51B:
undetectable		 2o01A-5t51B:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5t51 KLLA0F02343P
(Kluyveromyces
lactis) 		3 / 3 LEU A  46
TYR A  45
GLN A  48
 None
 0.73A 2wekA-5t51A:
undetectable		 2wekA-5t51A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5t51 KLLA0E05809P
KLLA0F02343P
(Kluyveromyces
lactis) 		4 / 6 THR A  65
ILE A  52
TYR B  48
ASP A  59
 None
 1.11A 3q70A-5t51A:
undetectable		 3q70A-5t51A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5t51 KLLA0F02343P
(Kluyveromyces
lactis) 		3 / 3 ASP A  77
LYS A  78
ASP A  81
 None
 0.49A 4a7tA-5t51A:
undetectable		 4a7tA-5t51A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5t51 KLLA0F02343P
KLLA0E05809P
(Kluyveromyces
lactis;
Kluyveromyces
lactis) 		3 / 3 ASP B  94
LYS B  89
LEU A  16
 None
 1.05A 4ptjA-5t51B:
undetectable		 4ptjA-5t51B:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5t51 KLLA0E05809P
(Kluyveromyces
lactis) 		4 / 5 GLU B  87
PHE B  81
ASP B  78
HIS B  82
 None
 1.21A 6b58A-5t51B:
2.9		 6b58A-5t51B:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_C_ACTC609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5t51 KLLA0E05809P
(Kluyveromyces
lactis) 		4 / 5 GLU B  87
PHE B  81
ASP B  78
HIS B  82
 None
 1.27A 6b58C-5t51B:
0.8		 6b58C-5t51B:
11.91