SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		4 / 6 TRP A  33
GLY A  67
ASN A  35
PRO A  69
 NDP  A 404 (-3.4A)
None
NDP  A 404 ( 4.6A)
None
 1.33A 1dedA-5t79A:
8.6		 1dedA-5t79A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 GLY A  99
ALA A  98
GLY A 166
ILE A 167
ALA A 152
 None
 0.93A 2b60A-5t79A:
undetectable		 2b60A-5t79A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 ILE A 327
GLU A 268
LEU A 277
MET A 280
ALA A 271
 None
 1.13A 2noaA-5t79A:
undetectable		 2noaA-5t79A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		4 / 7 LEU A  49
GLN A  50
PHE A  53
PHE A  60
 None
 1.03A 3ag2C-5t79A:
undetectable		 3ag2C-5t79A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 GLY A 217
VAL A 165
GLY A 166
ILE A 167
ILE A 219
 None
 0.89A 3ekqA-5t79A:
undetectable		 3ekqA-5t79A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		4 / 8 THR A  40
GLY A  67
ALA A  73
ILE A  80
 None
 0.81A 3jusA-5t79A:
undetectable		 3jusA-5t79A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		4 / 8 THR A  40
GLY A  67
ALA A  73
ILE A  80
 None
 0.81A 3jusA-5t79A:
undetectable		 3jusA-5t79A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 9 GLY A  99
ALA A  98
GLY A 166
ILE A 167
LEU A 116
 None
 0.96A 3ogpB-5t79A:
undetectable		 3ogpB-5t79A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 VAL A 203
PRO A 194
HIS A  59
SER A  29
GLY A  31
 None
None
None
None
NDP  A 404 (-3.0A)
 1.43A 4hvcA-5t79A:
undetectable		 4hvcA-5t79A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 LEU A 211
PRO A 194
HIS A  59
SER A  29
GLY A  31
 None
None
None
None
NDP  A 404 (-3.0A)
 1.33A 4hvcB-5t79A:
undetectable		 4hvcB-5t79A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 VAL A 203
PRO A 194
HIS A  59
SER A  29
GLY A  31
 None
None
None
None
NDP  A 404 (-3.0A)
 1.42A 4olfA-5t79A:
undetectable		 4olfA-5t79A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 LEU A 211
PRO A 194
HIS A  59
SER A  29
GLY A  31
 None
None
None
None
NDP  A 404 (-3.0A)
 1.34A 4q15A-5t79A:
undetectable		 4q15A-5t79A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 LEU A 211
PRO A 194
HIS A  59
SER A  29
GLY A  31
 None
None
None
None
NDP  A 404 (-3.0A)
 1.35A 4ydqA-5t79A:
undetectable		 4ydqA-5t79A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 ASP A   6
ASP A 306
GLN A 275
LYS A 276
GLY A 309
 None
NDP  A 404 (-3.5A)
None
NDP  A 404 ( 4.3A)
None
 1.29A 5hfjH-5t79A:
undetectable		 5hfjH-5t79A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		5 / 12 VAL A 203
PRO A 194
HIS A  59
SER A  29
GLY A  31
 None
None
None
None
NDP  A 404 (-3.0A)
 1.42A 5xioA-5t79A:
undetectable		 5xioA-5t79A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE
(Salmonella
enterica) 		4 / 7 GLY A 166
PHE A 135
VAL A 157
SER A  95
 None
 1.05A 6hu9S-5t79A:
undetectable
6hu9q-5t79A:
undetectable		 6hu9S-5t79A:
16.17
6hu9q-5t79A:
18.60