SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5t7c HIPPOCALCIN-LIKE
PROTEIN 1
(Homo
sapiens) 		3 / 3 GLU A  84
ASP A  81
ASP A  73
 None
 0.69A 4gc9A-5t7cA:
undetectable		 4gc9A-5t7cA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 5t7c HIPPOCALCIN-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 7 PRO A 145
GLU A 146
GLU A 123
THR A  40
 None
 1.22A 4uacA-5t7cA:
undetectable		 4uacA-5t7cA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5t7c HIPPOCALCIN-LIKE
PROTEIN 1
(Homo
sapiens) 		3 / 3 TYR A 129
ARG A 148
THR A 144
 None
 0.93A 5z84J-5t7cA:
undetectable		 5z84J-5t7cA:
20.53