SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5t7k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 5t7k AOAA13
(Aspergillus
oryzae) 		4 / 5 ASP A  38
LEU A  37
MET A  94
ARG A 157
 None
 1.23A 2gj5A-5t7kA:
undetectable		 2gj5A-5t7kA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5t7k AOAA13
(Aspergillus
oryzae) 		3 / 3 ARG A  44
GLY A  43
SER A 212
 None
 0.62A 2xctB-5t7kA:
undetectable		 2xctB-5t7kA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 5t7k AOAA13
(Aspergillus
oryzae) 		3 / 3 ARG A  12
GLU A  80
TYR A  73
 None
 0.71A 3k37B-5t7kA:
undetectable		 3k37B-5t7kA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 5t7k AOAA13
(Aspergillus
oryzae) 		5 / 12 GLY A 131
ASP A 129
ASP A 126
ARG A  98
ILE A 105
 None
 1.12A 3n3iA-5t7kA:
undetectable		 3n3iA-5t7kA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5t7k AOAA13
(Aspergillus
oryzae) 		4 / 5 ASN A  59
PRO A  47
GLY A  49
ASP A  36
 None
None
None
ZN  A 403 (-3.4A)
 1.11A 4n48B-5t7kA:
undetectable		 4n48B-5t7kA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5t7k AOAA13
(Aspergillus
oryzae) 		4 / 7 GLY A   2
PHE A 218
ASP A  90
PHE A 166
 HIC  A   1 ( 2.3A)
None
None
None
 0.92A 5hieA-5t7kA:
undetectable		 5hieA-5t7kA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5t7k AOAA13
(Aspergillus
oryzae) 		4 / 6 PRO A 202
VAL A 199
VAL A  81
ILE A  99
 None
 0.65A 5pbeA-5t7kA:
undetectable		 5pbeA-5t7kA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5t7k AOAA13
(Aspergillus
oryzae) 		4 / 4 GLY A  46
LEU A 225
VAL A  42
GLU A 125
 None
 1.21A 5yw0A-5t7kA:
undetectable		 5yw0A-5t7kA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5t7k AOAA13
(Aspergillus
oryzae) 		4 / 6 LEU A  37
ASP A  38
ASP A 129
ARG A 157
 None
 1.02A 6g31J-5t7kA:
undetectable		 6g31J-5t7kA:
14.43